Protein Overview: levy-PA, FBpp0309930

General Information:
Name(s) found:	FBpp0309930 [FlyBase] levy-PA / FBpp0071970 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7291601\|gb\|AAF47024.1\| levy [Drosophila melanogaster] [NCBI NR] gi\|20130301\|ref\|NP_611805.1\| levy [Drosophila melanogaster] [NCBI NR] gi\|17944459\|gb\|AAL48119.1\| RH03295p [Drosophila melanogaster] [NCBI NR] type=protein; loc=2R:join(19435813..19435909,19436061..19436293); ID=FBpp0309930; name=levy-PB; parent=FBgn0034877,FBtr0343265; dbxref=FlyBase:FBpp0309930,FlyBase_Annotation_IDs:CG17280-PB; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r5.56; species=Dmel; [FlyBase] The gene levy is referred to in FlyBase by the symbol Dmel\levy (CG17280, FBgn0034877). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19435763..19436505. It has the cytological map location 59E3. There is experimental evidence that it has the molecular function</span>: cytochrome-c oxidase activity; enzyme regulator activity. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; mitochondrial electron transport, cytochrome c to oxygen. 5 alleles are reported. The phenotypes of these alleles are annotated with: optic lobe; adult brain. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG17280-PA translation from_gene[CG17280 CG17280 FBgn0034877] seq_release:3 mol_weight=12482 cds_boundaries:(2R:18,591,858..18,592,335[+]) aa_length:109 transcript_info:[CG17280-RA seq_release:3] gene_info:[gene symbol:CG17280 FBgn0034877 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta] (Q9W1N3) CG17280 protein (RH03295p) [DrosMelano7227.FASTAC.txt] (AE003461) CG17280 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG17280-PA [Drosophila melanogaster]gi\|17944459\|gb\|AAL48119.1\| RH03295p [Drosophila melanogaster]gi\|20130301\|ref\|NP_611805.1\| CG17280-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2R:join(19435813..19435909,19436061..19436293); ID=FBpp0071970; name=levy-PA; parent=FBgn0034877,FBtr0072061; dbxref=FlyBase:FBpp0071970,FlyBase_Annotation_IDs:CG17280-PA,GB_protein:AAF47024.1,REFSEQ:NP_611805,GB_protein:AAF47024; MD5=09 [fly-100309-contam.fasta] CG17280-PA [Drosophila melanogaster] [nr-271106-contam.fasta] RH03295p [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2R:join(19435813..19435909,19436061..19436293); ID=FBpp0071970; name=levy-PA; parent=FBgn0034877,FBtr0072061; dbxref=FlyBase:FBpp0071970,FlyBase_Annotation_IDs:CG17280-PA,GB_protein:AAF47024.1,REFSEQ:NP_611805,GB_protein:AAF47024; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2R:join(19435813..19435909,19436061..19436293); ID=FBpp0071970; name=levy-PA; parent=FBgn0034877,FBtr0072061; dbxref=FlyBase:FBpp0071970,FlyBase_Annotation_IDs:CG17280-PA,GB_protein:AAF47024.1,REFSEQ:NP_611805,GB_protein:AAF47024; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Levy OS=Drosophila melanogaster GN=levy PE=3 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2R:join(19435813..19435909,19436061..19436293); ID=FBpp0071970; name=levy-PA; parent=FBgn0034877,FBtr0072061; dbxref=FlyBase:FBpp0071970,FlyBase_Annotation_IDs:CG17280-PA,GB_protein:AAF47024.1,REFSEQ:NP_611805,GB_protein:AAF47024,FlyMine:FBpp0071970,modMine:FBpp0071970; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2R:join(23548290..23548386,23548538..23548770); ID=FBpp0071970; name=levy-PA; parent=FBgn0034877,FBtr0072061; dbxref=FlyBase:FBpp0071970,FlyBase_Annotation_IDs:CG17280-PA,GB_protein:AAF47024.1,REFSEQ:NP_611805,GB_protein:AAF47024,FlyMine:FBpp0071970,modMine:FBpp0071970; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:join(23548290..23548386,23548538..23548770); ID=FBpp0309930; name=levy-PB; parent=FBgn0034877,FBtr0343265; dbxref=GB_protein:AHN56565,REFSEQ:NP_001286770,FlyBase:FBpp0309930,FlyBase_Annotation_IDs:CG17280-PB; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2R:join(23548290..23548386,23548538..23548770); ID=FBpp0071970; name=levy-PA; parent=FBgn0034877,FBtr0072061; dbxref=FlyBase:FBpp0071970,FlyBase_Annotation_IDs:CG17280-PA,GB_protein:AAF47024.1,REFSEQ:NP_611805,GB_protein:AAF47024,FlyMine:FBpp0071970,modMine:FBpp0071970; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2R:join(23548290..23548386,23548538..23548770); ID=FBpp0309930; name=levy-PB; parent=FBgn0034877,FBtr0343265; dbxref=GB_protein:AHN56565,REFSEQ:NP_001286770,FlyBase:FBpp0309930,FlyBase_Annotation_IDs:CG17280-PB; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Levy, isoform A OS=Drosophila melanogaster GN=levy PE=1 SV=1 [DROME.fasta.20160308] FBpp0071970 type=protein; loc=2R:join(23548290..23548386,23548538..23548770); ID=FBpp0071970; name=levy-PA; parent=FBgn0034877,FBtr0072061; dbxref=FlyBase:FBpp0071970,FlyBase_Annotation_IDs:CG17280-PA,GB_protein:AAF47024.1,REFSEQ:NP_611805,GB_protein:AAF47024,FlyMine:FBpp0071970,modMine:FBpp0071970; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0309930 type=protein; loc=2R:join(23548290..23548386,23548538..23548770); ID=FBpp0309930; name=levy-PB; parent=FBgn0034877,FBtr0343265; dbxref=GB_protein:AHN56565,REFSEQ:NP_001286770,FlyBase:FBpp0309930,FlyBase_Annotation_IDs:CG17280-PB; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2R:join(23548290..23548386,23548538..23548770); ID=FBpp0071970; name=levy-PA; parent=FBgn0034877,FBtr0072061; dbxref=FlyBase:FBpp0071970,FlyBase_Annotation_IDs:CG17280-PA,GB_protein:AAF47024.1,REFSEQ:NP_611805,GB_protein:AAF47024,UniProt/TrEMBL:Q9W1N3,FlyMine:FBpp0071970,modMine:FBpp0071970; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2R:join(23548290..23548386,23548538..23548770); ID=FBpp0309930; name=levy-PB; parent=FBgn0034877,FBtr0343265; dbxref=GB_protein:AHN56565,REFSEQ:NP_001286770,FlyBase:FBpp0309930,FlyBase_Annotation_IDs:CG17280-PB,UniProt/TrEMBL:Q9W1N3; MD5=09db1b48eeb1a5d9e29325a4005a83e0; length=109; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	109 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IDA] microsome [IDA] mitochondrial respiratory chain complex IV [IC][ISS]
Biological Process:	determination of adult lifespan [IMP] mitochondrial electron transport, cytochrome c to oxygen [IMP][ISS]
Molecular Function:	cytochrome-c oxidase activity [IMP][ISS] enzyme regulator activity [IMP]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MSAILNHAIR RQFGASAARN MSGTAAVAGE HSGGYKVWKR LSFFVAVPAV GLCMLNAYLK 60 61 HQEEHDKPRQ EFVKYDYLRR REKRFPWGEG QKSLFHNPHV NALPDGYEH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

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No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..109]	PSI-BLAST	28.0	Mitochondrial cytochrome c oxidase subunit VIa

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
cytochrome-c oxidase activity	12.2317532545955	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	12.2317532545955	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	12.2317532545955	bayes_pls_golite062009
heme-copper terminal oxidase activity	11.9189904362651	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	5.77104248101315	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	5.61858135414369	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	5.0189825255034	bayes_pls_golite062009
oxidoreductase activity	4.93709142475202	bayes_pls_golite062009
cation transmembrane transporter activity	4.77145907631723	bayes_pls_golite062009
ion transmembrane transporter activity	4.57436007698077	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.16699951799043	bayes_pls_golite062009
substrate-specific transporter activity	3.97113110639524	bayes_pls_golite062009
catalytic activity	0.448769452796145	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

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Source: Reynolds et al. 2008. Manuscript submitted

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