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Protein Overview: Dcr-2-PA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

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No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..361] PSI-BLAST 85.0 No description for 2i4iA was found.
2 View Details [362..609] PSI-BLAST 19.69897 Initiation factor 4a
3 View Details [610..696] deduced N/A No confident structure predictions are available.
4 View Details [697..1174] FFAS03 3.88 Crystal structure of full length Argonaute from Pyrococcus furiosus
5 View Details [1175..1336] PSI-BLAST 12.0 Crystal Structure of Dicer from Giardia intestinalis
6 View Details [1337..1420] deduced N/A No confident structure predictions are available.
7 View Details [1421..1722] PSI-BLAST 44.045757 RNase III endonuclease catalytic domain; RNase III, C-terminal domain

Functions predicted (by domain):

# Gene Ontology predictions
1 No functions predicted.
2
Term Confidence Notes
  • nucleoside-triphosphatase activity
  • 2.85628130885095 bayes_pls_golite062009
  • pyrophosphatase activity
  • 2.78950165917982 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
  • 2.76996223962376 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
  • 2.7670079419026 bayes_pls_golite062009
  • binding
  • 2.64537357529343 bayes_pls_golite062009
  • nucleic acid binding
  • 2.51683451033161 bayes_pls_golite062009
  • transporter activity
  • 2.36978240084485 bayes_pls_golite062009
  • ATPase activity
  • 2.26864012421561 bayes_pls_golite062009
  • transmembrane transporter activity
  • 2.18065576425044 bayes_pls_golite062009
  • DNA binding
  • 2.12258000781149 bayes_pls_golite062009
  • transcription regulator activity
  • 2.09345198747025 bayes_pls_golite062009
  • ATPase activity, coupled
  • 2.07184330056272 bayes_pls_golite062009
  • RNA helicase activity
  • 1.8459294302596 bayes_pls_golite062009
  • structural constituent of ribosome
  • 1.68112322593144 bayes_pls_golite062009
  • RNA binding
  • 1.60613159109369 bayes_pls_golite062009
  • hydrolase activity
  • 1.44476395406467 bayes_pls_golite062009
  • 1.44426272235796 bayes_pls_golite062009
  • substrate-specific transporter activity
  • 1.09373202836575 bayes_pls_golite062009
  • catalytic activity
  • 1.00104173493322 bayes_pls_golite062009
  • purine nucleotide binding
  • 0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
  • 0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
  • 0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
  • 0.920926158369519 bayes_pls_golite062009
  • transcription factor activity
  • 0.887108427603557 bayes_pls_golite062009
  • transcription repressor activity
  • 0.862685397469217 bayes_pls_golite062009
  • RNA-dependent ATPase activity
  • 0.74918137191219 bayes_pls_golite062009
  • structural molecule activity
  • 0.70126232242991 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
  • 0.696000326143746 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
  • 0.69117331267457 bayes_pls_golite062009
  • GTPase activity
  • 0.564061217246417 bayes_pls_golite062009
  • active transmembrane transporter activity
  • 0.434775387083003 bayes_pls_golite062009
  • ATP binding
  • 0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
  • 0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
  • 0.377870145186619 bayes_pls_golite062009
  • guanyl nucleotide binding
  • 0.296406132096546 bayes_pls_golite062009
  • GTP binding
  • 0.295705904888768 bayes_pls_golite062009
  • primary active transmembrane transporter activity
  • 0.294474570607914 bayes_pls_golite062009
  • guanyl ribonucleotide binding
  • 0.29028316917561 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
  • 0.282352478532746 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
  • 0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
  • 0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
  • 0.219157471322311 bayes_pls_golite062009
  • protein binding
  • 0.170837278876362 bayes_pls_golite062009
  • ion transmembrane transporter activity
  • 0.140475613064199 bayes_pls_golite062009
  • structure-specific DNA binding
  • 0.0869561319004262 bayes_pls_golite062009
  • helicase activity
  • 0.0775311459068899 bayes_pls_golite062009
  • signal sequence binding
  • 6.53725193420218E-4 bayes_pls_golite062009
    3 No functions predicted.
    4
    Term Confidence Notes
  • miRNA binding
  • 6.3992603035571 bayes_pls_golite062009
  • siRNA binding
  • 3.79765075105166 bayes_pls_golite062009
  • RNA binding
  • 3.38840041033834 bayes_pls_golite062009
  • nucleic acid binding
  • 2.6547106391215 bayes_pls_golite062009
  • binding
  • 2.47643238059712 bayes_pls_golite062009
  • protein binding
  • 1.26667637732731 bayes_pls_golite062009
  • translation initiation factor activity
  • 0.291763447649747 bayes_pls_golite062009
  • catalytic activity
  • 0.290929394811364 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.
    7
    Term Confidence Notes
  • bidentate ribonuclease III activity
  • 7.43273509253496 bayes_pls_golite062009
  • RNA binding
  • 5.07736605479017 bayes_pls_golite062009
  • nucleic acid binding
  • 4.05567898179605 bayes_pls_golite062009
  • double-stranded RNA binding
  • 3.47197996469543 bayes_pls_golite062009
  • binding
  • 3.29553298371996 bayes_pls_golite062009
  • structural constituent of ribosome
  • 3.02689668760645 bayes_pls_golite062009
  • siRNA binding
  • 2.97216972787792 bayes_pls_golite062009
  • DNA binding
  • 2.51691938562322 bayes_pls_golite062009
  • structural molecule activity
  • 2.49813032879923 bayes_pls_golite062009
  • transcription regulator activity
  • 2.36373437225982 bayes_pls_golite062009
  • ribonuclease III activity
  • 2.17541496872253 bayes_pls_golite062009
  • transcription repressor activity
  • 1.81658786565141 bayes_pls_golite062009
  • endoribonuclease activity
  • 1.62086478301433 bayes_pls_golite062009
  • protein binding
  • 1.43319050998069 bayes_pls_golite062009
  • transcription factor activity
  • 1.26788594164029 bayes_pls_golite062009
  • transcription activator activity
  • 0.434769929118334 bayes_pls_golite062009
  • mRNA binding
  • 0.404665180963566 bayes_pls_golite062009
  • single-stranded RNA binding
  • 0.35650576095599 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
  • 0.0407924801791524 bayes_pls_golite062009
  • pyrophosphatase activity
  • 0.0126548515995795 bayes_pls_golite062009
  • RNA helicase activity
  • 0.0112094156505713 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
  • 0.00332337214730594 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
  • 9.75560608640569E-4 bayes_pls_golite062009




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle