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Protein Overview: vis-PB

General Information:
Name(s) found: vis-PB / FBpp0087056 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene vismay is referred to in FlyBase by the symbol Dmel\vis (CG8821, FBgn0033748). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8395396..8398311. It has the cytological map location 49A10. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; transcription corepressor activity. There is experimental evidence that it is involved in the biological process</span>: spermatogenesis. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 524 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: spermatogenesis [IEP][IMP][IPI]
    regulation of transcription, DNA-dependent [IEA]
    regulation of transcription [IEA]
    Molecular Function: transcription factor activity [ISS]
    histone deacetylase binding [NAS]
    transcription corepressor activity [ISS]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISPEQEEVN MVLDRHVRQN IKDLMHEAHV HASLLNNEGR DRFHSDSSLD QDSLHAVVGN  60
   61 DLSTEQGANQ VQNYHDMMVD SEHHVDINGS LRKRRGNLPK SSVKILKRWL YEHRYNAYPS 120
  121 DAEKFTLSQE ANLTVLQVCN WFINARRRIL PEMIRREGND PLHFTISRRG KKVVGATEEV 180
  181 DGAGEIHEGI ANVLTNFEQY VQGPNGQMVK MEPEYEDSVI YSWQQAIANN PMGFQSLHSS 240
  241 LQATMIDKIK NYQMRKAAAI GGSAVGSGGA GGSSSNSSPA TSILPYSLFG QLPPEFDDEE 300
  301 KPRPPKRVRT RTVAAKSPRE NAKQAKQKTG NKQETMYCYK DSYGGIVVSP RSEGEESAQG 360
  361 YESCGPNSEE EVRFETSHDW QSVIKTVFGT EEVSTSAGNN PGTSGSKASV QNTAIWNRNQ 420
  421 TAKRDVNQQL TDFESELNII QASEIQTIDP TNSNQQDIGD NLQADEVFTG AEAEAGQSQL 480
  481 SALSQGTSSD EEGKYKCLYY LVETAMAVRQ NDDVQDDDFV YMGD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..67] deduced N/A No confident structure predictions are available.
    2 View Details [68..160] PSI-BLAST 8.522879 No description for 2dmnA was found.
    3 View Details [161..284] deduced N/A No confident structure predictions are available.
    4 View Details [285..524] MSA 6.165986 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle