Protein Overview: tup-PB

General Information:
Name(s) found:	tup-PB / FBpp0080662 [FlyBase]
Description(s) found: Found 21 descriptions. SHOW ALL	The gene tailup is referred to in FlyBase by the symbol Dmel\tup (CG10619, FBgn0003896). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:18859500..18881256. It has the cytological map location 37B1. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: torso signaling pathway; notum cell fate specification; motor axon guidance; dorsal closure; terminal region determination; amnioserosa maintenance; germ-band shortening; bristle morphogenesis. 19 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: adult segment; adult mesothoracic segment; appendage segment; cephalopharyngeal skeleton; organ system; pharyngeal sclerite; extended germ band embryo; late extended germ band embryo; peripheral nervous system; extraembryonic structure; metatarsus; unguis. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	465 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA][NAS]
Biological Process:	dorsal closure [IMP][TAS] torso signaling pathway [IGI] notum cell fate specification [IMP] germ-band shortening [IMP][TAS] terminal region determination [IGI] motor axon guidance [IMP] head involution [NAS] nervous system development [TAS] regulation of transcription, DNA-dependent [IEA] amnioserosa maintenance [IMP][TAS] regulation of transcription [IEA] regulation of transcription from RNA polymerase II promoter [NAS] bristle morphogenesis [IMP]
Molecular Function:	transcription factor activity [IEA] zinc ion binding [IEA] specific RNA polymerase II transcription factor activity [NAS] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVMAEIGGHL AHQLPLHNHN HNQTGLQPSL VMNHHLDLDC HGHDVIKKQR LSHCVGCGGQ  60
   61 IHDQYILRVA PDLEWHAACL KCQECRQFLD ESCTCFVRDG KTYCKRDYVR LFGTKCDKCG 120
  121 NSFSKNDFVM RAKTKIFHIE CFRCSACARQ LLPGDEFALR DAGALYCKED HDVLEKSSQS 180
  181 SLTSSSVESN NNISSSNNNN TNLSNNNHSS ELGSMSDSGS ESGSHKSIRD KRPSGPSDGK 240
  241 PTRVRTVLNE KQLHTLRTCY NANPRPDALM KEQLVEMTSL SPRVIRVWFQ NKRCKDKKKT 300
  301 IQMKLQMQQE KEGRKLGYGA MQGIPMIASS PVRHDSPLNL QGLDVQTYQP PWKALSDFAL 360
  361 HADLDSNGAI NTHTPAFQQL VNQMHGYDLN GMPILPPHPH SHPAQGPPHQ HPPPPGGPHN 420
  421 HQNQQPNQQP GGSSLDSGIT SHHHPDSTDS YVTYLESDDS MQGSP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: tup-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: