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Protein Overview: RUNX2_RAT

General Information:
Name(s) found: RUNX2_RAT [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • Runt-related transcription factor 2 (Fragments) OS=Rattus norvegicus GN=Runx2 PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 218 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA][IEA]
    transcription factor complex [UNKNOWN]
    cytoplasm [UNKNOWN]
    [NOT]nucleolus [UNKNOWN]
    Biological Process: regulation of fibroblast growth factor receptor signaling pathway [UNKNOWN]
    positive regulation of cell proliferation [UNKNOWN]
    osteoblast fate commitment [UNKNOWN]
    chondrocyte differentiation [UNKNOWN]
    chondrocyte development [UNKNOWN]
    regulation of transcription, DNA-dependent [IEA]
    odontogenesis of dentine-containing tooth [UNKNOWN]
    cell maturation [UNKNOWN]
    regulation of odontogenesis of dentine-containing tooth [UNKNOWN]
    positive regulation of osteoblast differentiation [UNKNOWN]
    positive regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    negative regulation of smoothened signaling pathway [UNKNOWN]
    regulation of osteoblast differentiation [TAS]
    positive regulation of ossification [IMP]
    skeletal system development [UNKNOWN]
    positive regulation of transcription, DNA-dependent [IDA]
    negative regulation of transcription [UNKNOWN]
    osteoblast differentiation [UNKNOWN]
    endochondral ossification [UNKNOWN]
    positive regulation of chondrocyte differentiation [UNKNOWN]
    regulation of ossification [UNKNOWN]
    Molecular Function: DNA binding [UNKNOWN]
    ATP binding [IEA]
    transcription factor activity [IDA][IEA][TAS]
    protein binding [UNKNOWN]
    chromatin binding [UNKNOWN]
    transcription factor binding [IPI]
    transcription activator activity [UNKNOWN][IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLHSPHKQPQ NHKCGANFLQ EDSKEALVFK WLISAGHYQP PRPTESVSAL STVHAVIFKA  60
   61 ASSIYNRGHK FYLEKKGGTM ASNSLFSAVT PCQQSFFWNK TLPVAFKVVA LGEVPDGTVV 120
  121 TVMAGNDENY SAELRNASAV MKNQVARFND LRFVGRSGRG KSFTLTITVF TNPPQVATYH 180
  181 RAIKVTVDGP REPRRHRQKL DDSKPSLFSD RLSDLGRI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle