General Information: |
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Name(s) found: |
TAP2_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 703 amino acids |
Gene Ontology: |
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Cellular Component: |
endoplasmic reticulum membrane
[IEA]
nucleus [UNKNOWN] MHC class I peptide loading complex [IDA] TAP complex [UNKNOWN][IDA] membrane [IEA] microsome [IDA] integral to membrane [UNKNOWN][IEA] integral to endoplasmic reticulum membrane [UNKNOWN] endoplasmic reticulum [UNKNOWN][IEA] |
Biological Process: |
transmembrane transport
[IEA]
protein complex assembly [IDA] protein transport [IEA] antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [UNKNOWN][IEA] positive regulation of antigen processing and presentation of peptide antigen via MHC class I [IMP] cytosol to ER transport [UNKNOWN] antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [UNKNOWN] peptide antigen transport [UNKNOWN][TAS] antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [UNKNOWN] intracellular transport of viral proteins in host cell [UNKNOWN] response to molecule of bacterial origin [UNKNOWN][IEA] protection from natural killer cell mediated cytotoxicity [IMP] antigen processing and presentation of endogenous peptide antigen via MHC class I [UNKNOWN][IDA] positive regulation of T cell mediated cytotoxicity [UNKNOWN][IDA] peptide transport [IMP] |
Molecular Function: |
ATPase activity
[IEA]
peptide antigen-transporting ATPase activity [UNKNOWN][TAS] ATPase activity, coupled to transmembrane movement of substances [IEA] peptide antigen binding [IDA] protein homodimerization activity [IDA][IPI] peptide transporter activity [UNKNOWN][IEA] MHC class I protein binding [IDA] ADP binding [IDA] TAP1 binding [UNKNOWN][IPI] TAP2 binding [IPI] transporter activity [UNKNOWN][IEA] nucleotide binding [IDA] ATP binding [UNKNOWN][IDA][IMP] protein binding [UNKNOWN] protein heterodimerization activity [IDA] tapasin binding [IPI] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MALSHPRPWA SLLLVDLALL GLLQSSLGTL LPPGLPGLWL EGTLRLGVLW GLLKVGGLLR 60 61 LVGTFLPLLC LTNPLFFSLR ALVGSTMSTS VVRVASASWG WLLADYGAVA LSLAVWAVLS 120 121 PAGAQEKEPG QENNRALMIR LLRLSKPDLP FLIVAFIFLA MAVWWEMFIP HYSGRVIDIL 180 181 GGDFDPDAFA SAIFFMCLFS VGSSLSAGCR GGSFLFAESR INLRIREQLF SSLLRQDLAF 240 241 FQETKTGELN SRLSSDTSLM SQWLSLNANI LLRSLVKVVG LYYFMLQVSP RLTFLSLLDL 300 301 PLTIAAEKVY NPRHQAVLKE IQDAVAKAGQ VVREAVGGLQ TVRSFGAEEQ EVRRYKEALE 360 361 RCRQLWWRRD LEKSLYLVIQ RVMALGMQVL ILNVGVQQIL AGEVTRGGLL SFLLYQEEVG 420 421 HHVQNLVYMY GDMLSNVGAA EKVFSYLDRR PNLPNPGTLA PPRLEGRVEF QDVSFSYPSR 480 481 PEKPVLQGLT FTLHPGKVTA LVGPNGSGKS TVAALLQNLY QPTGGQLLLD GEPLVQYDHH 540 541 YLHRQVVLVG QEPVLFSGSV KDNIAYGLRD CEDAQVMAAA QAACADDFIG EMTNGINTEI 600 601 GEKGSQLAVG QKQRLAIARA LVRNPRVLIL DEATSALDAE CEQALQTWRS QEDRTMLVIA 660 661 HRLHTVQNAD QVLVLKQGQL VEHDQLRDEQ DVYAHLVQQR LEA |
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