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Protein Overview: FPPS_RAT

General Information:
Name(s) found: FPPS_RAT [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • Farnesyl pyrophosphate synthase OS=Rattus norvegicus GN=Fdps PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 353 amino acids

    Gene Ontology:
    Cellular Component: peroxisome [IDA]
    soluble fraction [IDA]
    cytoplasm [IEA]
    mitochondrial matrix [IDA]
    mitochondrion [UNKNOWN]
    Biological Process: positive regulation of cell growth [IMP]
    male gonad development [IEP]
    cellular response to fatty acid [IEP]
    spermatogenesis [IEP]
    response to drug [IEP]
    cholesterol biosynthetic process [TAS]
    positive regulation of cholesterol biosynthetic process [IMP]
    isoprenoid biosynthetic process [IDA]
    response to testosterone stimulus [IEP]
    response to peptide hormone stimulus [IEP]
    farnesyl diphosphate biosynthetic process [IDA]
    response to cholesterol [IEP]
    Molecular Function: geranyltranstransferase activity [IDA][TAS]
    metal ion binding [IEA]
    dimethylallyltranstransferase activity [IEA]
    farnesyltranstransferase activity [IGI]
    transferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGDQKLDVH NQEKQNFIQH FSQIVKVLTE DELGHPEKGD AITRIKEVLE YNTVGGKYNR  60
   61 GLTVVQTFQE LVEPRKQDAE SLQRALTVGW CVELLQAFFL VLDDIMDSSY TRRGQICWYQ 120
  121 KPGIGLDAIN DALLLEAAIY RLLKFYCREQ PYYLNLLELF LQSSYQTEIG QTLDLITAPQ 180
  181 GQVDLGRYTE KRYKSIVKYK TAFYSFYLPI AAAMYMAGID GEKEHANALK ILLEMGEFFQ 240
  241 IQDDYLDLFG DPSVTGKVGT DIQDNKCSWL VVQCLLRATP QQRQILEENY GQKDPEKVAR 300
  301 VKALYEELDL RSVFFKYEED SYNRLKSLIE QCSAPLPPSI FLELANKIYK RRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle