Protein Overview: DLDH_MOUSE

General Information:
Name(s) found:	DLDH_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|74189198\|dbj\|BAE43405.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|31982856\|ref\|NP_031887.2\| dihydrolipoamide dehydrogenase [Mus musculus] [NCBI NR] gi\|13097204\|gb\|AAH03368.1\| Dihydrolipoamide dehydrogenase [Mus musculus] [NCBI NR] gi\|118572640\|sp\|O08749.2\|DLDH_MOUSE RecName: Full=Dihydrolipoyl dehydrogenase, mitochondrial; AltName: Full=Dihydrolipoamide dehydrogenase; Flags: Precursor [NCBI NR] Dihydrolipoyl dehydrogenase, mitochondrial OS=Mus musculus GN=Dld PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):12-25465454 Dihydrolipoamide dehydrogenase [hmr_yeast5_DM3-1_pombe.fasta] dihydrolipoamide dehydrogenase [HMR_022704-rand.fasta] Dihydrolipoamide dehydrogenase [ipi.MOUSE.v3.06.fasta] dihydrolipoamide dehydrogenase [Mus musculus]gi\|13097204\|gb\|AAH03368.1\| Dihydrolipoamide dehydrogenase [Mus musculus] [nrdb_11152004_Chlamydomonas] dihydrolipoamide dehydrogenase [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 Dihydrolipoamide dehydrogenase [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] Dihydrolipoyl dehydrogenase, mitochondrial precursor (Dihydrolipoamide dehydrogenase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Dihydrolipoamide dehydrogenase [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 DIHYDROLIPOAMIDE DEHYDROGENASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Dld Dihydrolipoyl dehydrogenase, mitochondrial [mouse-ipi-250309-contam.fasta] dihydrolipoamide dehydrogenase precursor [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Dld Dihydrolipoyl dehydrogenase, mitochondrial precursor [ipi.MOUSE_jw_12may08.contam.fasta] dihydrolipoyl dehydrogenase, mitochondrial precursor [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00874456.1\|SWISS-PROT:O08749\|ENSEMBL:ENSMUSP00000106481\|REFSEQ:NP_031887 Tax_Id=10090 Gene_Symbol=Dld Dihydrolipoyl dehydrogenase, mitochondrial [ipi.MOUSE.fasta.20090209] Dihydrolipoyl dehydrogenase, mitochondrial OS=Mus musculus GN=Dld [011711_HMR.fasta] sp\|O08749\|DLDH_MOUSE Dihydrolipoyl dehydrogenase, mitochondrial OS=Mus musculus GN=Dld PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	509 amino acids
Gene Ontology:
Cellular Component:	pyruvate dehydrogenase complex [UNKNOWN] cytoplasm [IEA] oxoglutarate dehydrogenase complex [UNKNOWN] mitochondrion [UNKNOWN][IDA] flagellum [IDA] acrosomal matrix [IDA]
Biological Process:	dihydrolipoamide metabolic process [UNKNOWN] regulation of membrane potential [IMP] sperm capacitation [IDA] acetyl-CoA biosynthetic process from pyruvate [UNKNOWN] mitochondrial electron transport, NADH to ubiquinone [IMP] proteolysis [IDA] oxidation reduction [IEA] cell redox homeostasis [IEA] 2-oxoglutarate metabolic process [UNKNOWN] lipoate metabolic process [UNKNOWN] gastrulation [IMP]
Molecular Function:	oxidoreductase activity [IEA] FAD binding [UNKNOWN] NAD or NADH binding [UNKNOWN] lipoamide binding [UNKNOWN] dihydrolipoyl dehydrogenase activity [UNKNOWN][IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSWSRVYRS LAKKGHFNRI SHGLQGVSSV PLRTYADQPI EADVTVIGSG PGGYVAAIKS  60
   61 AQLGFKTVCI EKNETLGGTC LNVGCIPSKA LLNNSHYYHM AHGKDFASRG IEIPEVRLNL 120
  121 EKMMEQKHSA VKALTGGIAH LFKQNKVVHV NGFGKITGKN QVTATKADGS TQVIDTKNIL 180
  181 VATGSEVTPF PGITIDEDTI VSSTGALSLK KVPEKLVVIG AGVIGVELGS VWQRLGADVT 240
  241 AVEFLGHVGG IGIDMEISKN FQRILQRQGF KFKLNTKVTG ATKKSDGKID VSVEAASGGK 300
  301 AEVITCDVLL VCIGRRPFTQ NLGLEELGIE LDPKGRIPVN NRFQTKIPNI YAIGDVVAGP 360
  361 MLAHKAEDEG IICVEGMAGG AVHIDYNCVP SVIYTHPEVA WVGKSEEQLK EEGIEFKIGK 420
  421 FPFAANSRAK TNADTDGMVK ILGHKSTDRV LGAHILGPGA GEMVNEAALA LEYGASCEDI 480
  481 ARVCHAHPTL SEAFREANLA AAFGKPINF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.92

Protein Overview: DLDH_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: