Protein Overview: SOX6_MOUSE

General Information:
Name(s) found:	SOX6_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|74208769\|dbj\|BAE21153.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|6755610\|ref\|NP_035575.1\| SRY (sex determining region Y)-box 6 isoform 1 [Mus musculus] [NCBI NR] pir\|\|S59121 SOX6 protein - mouse [NCBI NR] gi\|148685139\|gb\|EDL17086.1\| mCG141507, isoform CRA_a [Mus musculus] [NCBI NR] gi\|148685138\|gb\|EDL17085.1\| mCG141507, isoform CRA_a [Mus musculus] [NCBI NR] gi\|148685137\|gb\|EDL17084.1\| mCG141507, isoform CRA_a [Mus musculus] [NCBI NR] gi\|1351094\|sp\|P40645.2\|SOX6_MOUSE RecName: Full=Transcription factor SOX-6; AltName: Full=SOX-LZ [NCBI NR] gi\|1016686\|gb\|AAC52263.1\| SOX6 [NCBI NR] Transcription factor SOX-6 OS=Mus musculus GN=Sox6 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):7-103807342 Splice isoform 1 of P40645 Transcription factor SOX-6 [hmr_yeast5_DM3-1_pombe.fasta] SRY-box containing gene 6 [HMR_022704-rand.fasta] Splice Isoform 1 of Transcription factor SOX-6 [ipi.MOUSE.v3.06.fasta] SRY (sex determining region Y)-box 6 [Mus musculus]gi\|1351094\|sp\|P40645\|SOX6_MOUSE Transcription factor SOX-6 (SOX-LZ)gi\|2137788\|pir\|\|S59121 SOX6 protein - mousegi\|1016686\|gb\|AAC52263.1\| SOX6 [nrdb_11152004_Chlamydomonas] (NM_011445) SRY-box containing gene 6 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] SRY (sex determining region Y)-box 6 isoform 1 [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 Splice Isoform 1 of Transcription factor SOX-6 [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] Transcription factor SOX-6 (SOX-LZ) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mCG141507, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] SOX6 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SPLICE ISOFORM 1 OF TRANSCRIPTION FACTOR SOX-6 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Sox6 Isoform 1 of Transcription factor SOX-6 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Sox6 Isoform 1 of Transcription factor SOX-6 ENSMUSG00000051910 IPI00620986 IPI00849789 IPI00470047 IPI00623688 [IPIxENS.MOUSE_plus_REVERSE.fasta] transcription factor SOX-6 isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00620986.3\|SWISS-PROT:P40645-1\|TREMBL:Q3V1J7\|ENSEMBL:ENSMUSP00000072583\|REFSEQ:NP_035575 Tax_Id=10090 Gene_Symbol=Sox6 Isoform 1 of Transcription factor SOX-6 [ipi.MOUSE.fasta.20090209] Isoform 1 of Transcription factor SOX-6 OS=Mus musculus GN=Sox6 [011711_HMR.fasta] sp\|P40645\|SOX6_MOUSE Transcription factor SOX-6 OS=Mus musculus GN=Sox6 PE=1 SV=2 [uniprot.sptr.mouse.20130102] tr\|Q3V1J7\|Q3V1J7_MOUSE MCG141507, isoform CRA_a OS=Mus musculus GN=Sox6 PE=2 SV=1 [uniprot.sptr.mouse.20130102] MCG141507, isoform CRA_a OS=Mus musculus GN=Sox6 PE=2 SV=1 [mouse-uniprot-290313-contam.fasta]
Organism:	Mus musculus
Length:	827 amino acids
Gene Ontology:
Cellular Component:	nucleus [IC][IDA] transcription factor complex [IC]
Biological Process:	gene silencing [IMP] oligodendrocyte differentiation [IMP] astrocyte differentiation [UNKNOWN] transcription [IEA] cardiac cell differentiation [IDA] multicellular organismal development [IEA] hemopoiesis [IMP] cell morphogenesis [IMP] post-embryonic development [IMP] regulation of transcription, DNA-dependent [IDA] erythrocyte development [IMP] oligodendrocyte cell fate specification [IMP] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [IGI] negative regulation of transcription from RNA polymerase II promoter [IDA][IMP] negative regulation of transcription, DNA-dependent [IDA] in utero embryonic development [IMP] positive regulation of transcription, DNA-dependent [IDA] cell fate commitment [IGI] muscle cell differentiation [IDA] cartilage development [IGI]
Molecular Function:	DNA binding [IDA] transcription factor activity [IDA][IGI] protein binding [IPI] protein heterodimerization activity [IPI] sequence-specific DNA binding [IDA] promoter binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKQATSPF ACTADGEEAM TQDLTSREKE EGSDQHPASH LPLHPIMHNK PHSEELPTLV  60
   61 STIQQDADWD SVLSSQQRME SENNKLCSLY SFRNTSTSPH KPDEGSRERE IMNSVTFGTP 120
  121 ERRKGSLADV VDTLKQKKLE EMTRTEQEDS SCMEKLLSKD WKEKMERLNT SELLGEIKGT 180
  181 PESLAEKERQ LSTMITQLIS LREQLLAAHD EQKKLAASQI EKQRQQMDLA RQQQEQIARQ 240
  241 QQQLLQQQHK INLLQQQIQV QGHMPPLMIP IFPHDQRTLA AAAAAQQGFL FPPGITYKPG 300
  301 DNYPVQFIPS TMAAAAASGL SPLQLQKGHV SHPQINPRLK GISDRFGRNL DPSEHGGGHS 360
  361 YNHRQIEQLY AAQLASMQVS PGAKMPSTPQ PPNSAGAVSP TGIKNEKRGT SPVTQVKDET 420
  421 TAQPLNLSSR PKTAEPVKSP TSPTQNLFPA SKTSPVNLPN KSSIPSPIGG SLGRGSSLDI 480
  481 LSSLNSPALF GDQDTVMKAI QEARKMREQI QREQQQQPHG VDGKLSSMNN MGLSNCRTEK 540
  541 ERTRFENLGP QLTGKSSEDG KLGPGVIDLT RPEDAEGSKA MNGSAAKLQQ YYCWPTGGAT 600
  601 VAEARVYRDA RGRASSEPHI KRPMNAFMVW AKDERRKILQ AFPDMHNSNI SKILGSRWKS 660
  661 MSNQEKQPYY EEQARLSKIH LEKYPNYKYK PRPKRTCIVD GKKLRIGEYK QLMRSRRQEM 720
  721 RQFFTVGQQP QMPITTGTGV VYPGAITMAT TTPSPQMTSD CSSTSASPEP SLPVIQSTYG 780
  781 MKMDGASLAG NDMINGEDEM EAYDDYEDDP KSDYSSENEA PEPVSAN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.77

Protein Overview: SOX6_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: