YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: LYST_MOUSE

General Information:
Name(s) found: LYST_MOUSE [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • Lysosomal-trafficking regulator OS=Mus musculus GN=Lyst PE=1 SV=1 [Swiss-Prot]
    • Organism: Mus musculus
    Length: 3788 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    cytosol [IDA]
    Biological Process: lysosome organization [IMP]
    mast cell secretory granule organization [IMP]
    protein transport [IEA]
    blood coagulation [IMP]
    phospholipid metabolic process [IMP]
    transport [IEA]
    defense response to bacterium [IMP]
    phospholipid homeostasis [IMP]
    defense response to protozoan [IMP]
    microtubule-based process [IMP]
    T cell mediated immunity [IMP]
    melanosome organization [IMP]
    neutrophil mediated immunity [IMP]
    pigment granule organization [IMP]
    pigmentation [UNKNOWN][IMP]
    positive regulation of natural killer cell activation [IMP]
    response to drug [IMP]
    defense response to virus [IMP]
    secretion of lysosomal enzymes [IMP]
    leukocyte chemotaxis [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTDSNSLAR EFLIDVNQLC NAVVQRAEAR EEEEEETHMA TLGQYLVHGR GFLLLTKLNS  60
   61 IIDQALTCRE ELLTLLLSLL PLVWKIPVQE QQATDFNLPL SSDIILTKEK NSSLQKSTQG 120
  121 KLYLEGSAPS GQVSAKVNLF RKIRRQRKST HRYSVRDARK TQLSTSDSEG NSDEKSTVVS 180
  181 KHRRLHALPR FLTQSPKEGH LVAKPDPSAT KEQVLSDTMS VENSREVILR QDSNGDILSE 240
  241 PAALSILSNM NNSPFDLCHV LLSLLEKVCK FDIALNHNSS LALSVVPTLT EFLAGFGDCC 300
  301 NQSDTLEGQL VSAGWTEEPV ALVQRMLFRT VLHLMSVDVS TAEAMPESLR KNLTELLRAA 360
  361 LKIRACLEKQ PEPFSPRQKK TLQEVQEGFV FSKYRHRALL LPELLEGVLQ LLISCLQSAA 420
  421 SNPFYFSQAM DLVQEFIQHQ GFNLFGTAVL QMEWLLTRDG VPSEAAEHLK ALINSVIKIM 480
  481 STVKKVKSEQ LHHSMCTRKR HRRCEYSHFM QHHRDLSGLL VSAFKNQLSK SPFEETAEGD 540
  541 VQYPERCCCI AVCAHQCLRL LQQVSLSTTC VQILSGVHSV GICCCMDPKS VIAPLLHAFK 600
  601 LPALKAFQQH ILNVLSKLLV DQLGGAELSP RIKKAACNIC TVDSDQLAKL GETLQGTLCG 660
  661 AGPTSGLPSP SYRFQGILPS SGSEDLLWKW DALEAYQSFV FQEDRLHNIQ IANHICNLLQ 720
  721 KGNVVVQWKL YNYIFNPVLQ RGVELVHHCQ QLSIPSAQTH MCSQLKQYLP QEVLQIYLKT 780
  781 LPVLLKSRVI RDLFLSCNGV NHIIELNYLD GIRSHSLKAF ETLIVSLGEQ QKDAAVLDVD 840
  841 GLDIQQELPS LSVGPSLHKQ QASSDSPCSL RKFYASLREP DPKKRKTIHQ DVHINTINLF 900
  901 LCVAFLCVSK EADSDRESAN ESEDTSGYDS PPSEPLSHML PCLSLEDVVL PSPECLHHAA 960
  961 DIWSMCRWIY MLNSVFQKQF HRLGGFQVCH ELIFMIIQKL FRSHTEDQGR RQGEMSRNEN1020
 1021 QELIRISYPE LTLKGDVSSA TAPDLGFLRK SADSVRGFQS QPVLPTSAEQ IVATESVPGE1080
 1081 RKAFMSQQSE TSLQSIRLLE SLLDICLHSA RACQQKMELE LPSQGLSVEN ILCELREHLS1140
 1141 QSKVAETELA KPLFDALLRV ALGNHSADLG PGDAVTEKSH PSEEELLSQP GDFSEEAEDS1200
 1201 QCCSLKLLGE EEGYEADSES NPEDVDTQDD GVELNPEAEG FSGSIVSNNL LENLTHGEII1260
 1261 YPEICMLGLN LLSASKAKLD VLAHVFESFL KIVRQKEKNI SLLIQQGTVK ILLGGFLNIL1320
 1321 TQTNSDFQAC QRVLVDLLVS LMSSRTCSED LTLLWRIFLE KSPCTEILLL GIHKIVESDF1380
 1381 TMSPSQCLTF PFLHTPSLSN GVLSQKPPGI LNSKALGLLR RARISRGKKE ADRESFPYRL1440
 1441 LSSWHIAPIH LPLLGQNCWP HLSEGFSVSL VGLMWNTSNE SESAAERGKR VKKRNKPSVL1500
 1501 EDSSFEGAEG DRPEVTESIN PGDRLIEDGC IHLISLGSKA LMIQVWADPH SGTFIFRVCM1560
 1561 DSNDDTKAVS LAQVESQENI FFPSKWQHLV LTYIQHPQGK KNVHGEISIW VSGQRKTDVI1620
 1621 LDFVLPRKTS LSSDSNKTFC MIGHCLTSQE ESLQLAGKWD LGNLLLFNGA KIGSQEAFFL1680
 1681 YACGPNYTSI MPCKYGQPVI DYSKYINKDI LRCDEIRDLF MTKKEVDVGL LIESLSVVYT1740
 1741 TCCPAQYTIY EPVIRLKGQV KTQPSQRPFS SKEAQSILLE PSQLKGLQPT ECKAIQGILH1800
 1801 EIGGAGTFVF LFARVVELSS CEETQALALR VILSLIKYSQ QRTQELENCN GLSMIHQVLV1860
 1861 KQKCIVGFHI LKTLLEGCCG EEVIHVSEHG EFKLDVESHA IIQDVKLLQE LLLDWKIWNK1920
 1921 AEQGVWETLL AALEVLIRVE HHQQQFNIKQ LLNAHVVHHF LLTCQVLQEH REGQLTSMPR1980
 1981 EVCRSFVKII AEVLGSPPDL ELLTVIFNFL LAVHPPTNTY VCHNPTNFYF SLHIDGKIFQ2040
 2041 EKVQSLAYLR HSSSGGQAFP SPGFLVISPS AFTAAPPEGT SSSNIVPQRM AAQMVRSRSL2100
 2101 PAFPTYLPLI RAQKLAASLG FSVDKLQNIA DANPEKQNLL GRPYALKTSK EEAFISSCES2160
 2161 AKTVCEMEAL LGAHASANGV SRGSPRFPRA RVDHKDVGTE PRSDDDSPGD ESYPRRPDNL2220
 2221 KGLASFQRSQ STVASLGLAF PSQNGSAVAS RWPSLVDRNA DDWENFTFSP AYEASYNRAT2280
 2281 STHSVIEDCL IPICCGLYEL LSGVLLVLPD AMLEDVMDRI IQADILLVLV NHPSPAIQQG2340
 2341 VIKLLHAYIN RASKEQKDKF LKNRGFSLLA NQLYLHRGTQ ELLECFVEMF FGRPIGLDEE2400
 2401 FDLEEVKHME LFQKWSVIPV LGLIETSLYD NVLLHNALLL LLQVLNSCSK VADMLLDNGL2460
 2461 LYVLCNTVAA LNGLEKNIPV NEYKLLACDI QQLFIAVTIH ACSSSGTQYF RVIEDLIVLL2520
 2521 GYLHNSKNKR TQNMALALQL RVLQAALEFI RSTANHDSES PVHSPSAHRH SVPPKRRSIA2580
 2581 GSRKFPLAQT ESLLMKMRSV ASDELHSMMQ RRMSQEHPSQ ASEAELAQRL QRLTILAVNR2640
 2641 IIYQELNSDI IDILRTPENT SQSKTSVSQT EISEEDMHHE QPSVYNPFQK EMLTYLLDGF2700
 2701 KVCIGSSKTS VSKQQWTKIL GSCKETLRDQ LGRLLAHILS PTHTVQERKQ ILEIVHEPAH2760
 2761 QDILRDCLSP SPQHGAKLVL YLSELIHNHQ DELSEEEMDT AELLMNALKL CGHKCIPPSA2820
 2821 PSKPELIKII REEQKKYESE ESVSKGSWQK TVNNNQQSLF QRLDFKSKDI SKIAADITQA2880
 2881 VSLSQGIERK KVIQHIRGMY KVDLSASRHW QECIQQLTHD RAVWYDPIYY PTSWQLDPTE2940
 2941 GPNRERRRLQ RCYLTIPNKY LLRDRQKSEG VLRPPLSYLF EDKTHSSFSS TVKDKAASES3000
 3001 IRVNRRCISV APSRETAGEL LLGKCGMYFV EDNASDAVES SSLQGELEPA SFSWTYEEIK3060
 3061 EVHRRWWQLR DNAVEIFLTN GRTLLLAFDN NKVRDDVYQS ILTNNLPNLL EYGNITALTN3120
 3121 LWYSGQITNF EYLTHLNKHA GRSFNDLMQY PVFPFILSDY VSETLDLNDP SIYRNLSKPI3180
 3181 AVQYKEKEDR YVDTYKYLEE EYRKGAREDD PMPPVQPYHY GSHYSNSGTV LHFLVRMPPF3240
 3241 TKMFLAYQDQ SFDIPDRTFH STNTTWRLSS FESMTDVKEL IPEFFYLPEF LVNREGFDFG3300
 3301 VRQNGERVNH VNLPPWARND PRLFILIHRQ ALESDHVSQN ICHWIDLVFG YKQKGKASVQ3360
 3361 AINVFHPATY FGMDVSAVED PVQRRALETM IKTYGQTPRQ LFHTAHASRP GAKLNIEGEL3420
 3421 PAAVGLLVQF AFRETREPVK EVTHPSPLSW IKGLKWGEYV GSPSAPVPVV CFSQPHGERF3480
 3481 GSLQALPTRA ICGLSRNFCL LMTYNKEQGV RSMNNTNIQW SAILSWGYAD NILRLKSKQS3540
 3541 EPPINFIQSS QQHQVTSCAW VPDSCQLFTG SKCGVITAYT NRLTSSTPSE IEMESQMHLY3600
 3601 GHTEEITGLC VCKPYSVMIS VSRDGTCIVW DLNRLCYVQS LAGHKSPVTA VSASETSGDI3660
 3661 ATVCDSAGGG SDLRLWTVNG DLVGHVHCRE IICSVAFSNQ PEGVSINVIA GGLENGIVRL3720
 3721 WSTWDLKPVR EITFPKSNKP IISLTFSCDG HHLYTANSEG TVIAWCRKDQ QRVKLPMFYS3780
 3781 FLSSYAAG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle