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Protein Overview: MED4_MOUSE

General Information:
Name(s) found: MED4_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|62900597|sp|Q9CQA5.1|MED4_MOUSE RecName: Full=Mediator of RNA polymerase II transcription subunit 4; AltName: Full=Mediator complex subunit 4 [NCBI NR]
  • gi|19354324|gb|AAH24950.1| Mediator of RNA polymerase II transcription, subunit 4 homolog (yeast) [Mus musculus] [NCBI NR]
  • gi|148703908|gb|EDL35855.1| mediator of RNA polymerase II transcription, subunit 4 homolog (yeast), isoform CRA_a [Mus musculus] [NCBI NR]
  • gi|13385626|ref|NP_080395.1| vitamin D receptor interacting protein [Mus musculus] [NCBI NR]
  • gi|12846310|dbj|BAB27118.1| unnamed protein product [Mus musculus] [NCBI NR]
  • gi|12845586|dbj|BAB26809.1| unnamed protein product [Mus musculus] [NCBI NR]
  • Mediator of RNA polymerase II transcription subunit 4 OS=Mus musculus GN=Med4 PE=2 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):14-63963816 2410046H15Rik protein [hmr_yeast5_DM3-1_pombe.fasta]
  • vitamin D receptor interacting protein; p36 TRAP/SMCC/PC2 subunit [HMR_022704-rand.fasta]
  • Mediator complex subunit 4 [ipi.MOUSE.v3.06.fasta]
  • vitamin D receptor interacting protein [Mus musculus]gi|19354324|gb|AAH24950.1| Vitamin D receptor interacting protein [Mus musculus]gi|12846310|dbj|BAB27118.1| unnamed protein product [Mus musculus]gi|12845586|dbj|BAB26809.1| unnamed protein product [ [nrdb_11152004_Chlamydomonas]
  • (NM_026119) RIKEN cDNA 2410046H15 [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • vitamin D receptor interacting protein [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta]
  • Tax_Id=10090 Mediator complex subunit 4 [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta]
  • Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • mediator of RNA polymerase II transcription, subunit 4 homolog (yeast), isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Mediator of RNA polymerase II transcription, subunit 4 homolog (yeast) [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 MUS MUSCULUS ES CELLS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:2410046H15 PRODUCT:VITAMIN D RECEPTOR-INTERACTING PROTEIN COMPLEX COMPONENT DRIP36 HOMOLOG [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Mediator complex subunit 4 (Mediator of RNA polymerase II transcription subunit 4) [nr-271106-contam.fasta]
  • mediator of RNA polymerase II transcription subunit 4 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta]
  • Isoform 1 of Mediator of RNA polymerase II transcription subunit 4 OS=Mus musculus GN=Med4 [011711_HMR.fasta]
  • Tax_Id=10090 Gene_Symbol=Med4 Isoform 1 of Mediator of RNA polymerase II transcription subunit 4 [EBI-IPI_mouse_2_08-18-2011_reversed.fasta]
  • sp|Q9CQA5|MED4_MOUSE Mediator of RNA polymerase II transcription subunit 4 OS=Mus musculus GN=Med4 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 270 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    mediator complex [UNKNOWN]
    Biological Process: biological_process [ND]
    transcription [IEA]
    regulation of transcription [IEA]
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASSSGEKE KERMGGVSGM AGLGSTRERL LSALEDLEVL SRELIEMLAI SRNQKLLQLE  60
   61 EENQVLELLI HRDGDFQELM KLALNQGKVH HEMQALEKEV EKRDSDIQQL QKQLKEAEQI 120
  121 LATAVYQAKE KLKSIEKARK GAISSEEIIK YAHRISASNA VCAPLTWVPG DPRRPYPTDL 180
  181 EMRSGLLGQM NNPSTSGVNG HLPGDALAAG RLPDVLAPQY PWQSNDMSVN MLPPNHSSDF 240
  241 LLEPPGHNKE NEDDVEVMST DSSSSSSDSD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..270] FFAS03 1.57 Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle