Protein Overview: AVR2B_MOUSE

General Information:
Name(s) found:	AVR2B_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6680634\|ref\|NP_031423.1\| activin A receptor, type IIB [Mus musculus] [NCBI NR] pir\|\|A40829 activin receptor isoform IIB1 - mouse [NCBI NR] gi\|191669\|gb\|AAA37172.1\| activin type IIB receptor [NCBI NR] gi\|114727\|sp\|P27040.1\|AVR2B_MOUSE RecName: Full=Activin receptor type-2B; AltName: Full=Activin receptor type IIB; Short=ACTR-IIB; Flags: Precursor [NCBI NR] (P27040) Activin receptor type IIB precursor (EC 2.7.1.37) (ACTR-IIB) [Swiss-Prot] Activin receptor type-2B OS=Mus musculus GN=Acvr2b PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):9-119507214 Splice isoform ActR-IIB1 of P27040 Activin receptor type IIB precursor [hmr_yeast5_DM3-1_pombe.fasta] activin receptor IIB [HMR_022704-rand.fasta] Splice Isoform ActR-IIB1 of Activin receptor type IIB precursor [ipi.MOUSE.v3.06.fasta] activin receptor IIB [Mus musculus]gi\|114727\|sp\|P27040\|AVRB_MOUSE Activin receptor type IIB precursor (ACTR-IIB)gi\|284692\|pir\|\|A40829 activin receptor isoform IIB1 - mousegi\|191669\|gb\|AAA37172.1\| activin type IIB receptor [nrdb_11152004_Chlamydomonas] Tax_Id=10090 Splice Isoform ActR-IIB1 of Activin receptor type 2B precursor [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] (NM_007397) activin receptor IIB [Mus musculus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] activin receptor IIB [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 Splice Isoform ActR-IIB1 of Activin receptor type IIB precursor [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] Activin receptor type-2B precursor (Activin receptor type IIB) (ACTR-IIB) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] activin type IIB receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 SPLICE ISOFORM 1 OF ACTIVIN RECEPTOR TYPE IIB PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Acvr2b Isoform ActR-IIB1 of Activin receptor type-2B [mouse-ipi-250309-contam.fasta] activin A receptor, type IIB precursor [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Acvr2b Isoform ActR-IIB1 of Activin receptor type-2B precursor [ipi.MOUSE_jw_12may08.contam.fasta] Activin receptor type 2B precursor (Activin receptor type IIB) (ACTR-IIB) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Acvr2b Isoform ActR-IIB1 of Activin receptor type-2B precursor ENSMUSG00000061393 IPI00114037 IPI00222110 IPI00222111 IPI00222112 [IPIxENS.MOUSE_plus_REVERSE.fasta] activin receptor type-2B precursor [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00114037.3\|SWISS-PROT:P27040-1\|ENSEMBL:ENSMUSP00000035093\|REFSEQ:NP_031423 Tax_Id=10090 Gene_Symbol=Acvr2b Isoform ActR-IIB1 of Activin receptor type-2B [ipi.MOUSE.fasta.20090209] Isoform ActR-IIB1 of Activin receptor type-2B OS=Mus musculus GN=Acvr2b [011711_HMR.fasta] sp\|P27040\|AVR2B_MOUSE Activin receptor type-2B OS=Mus musculus GN=Acvr2b PE=1 SV=1 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	536 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA]
Biological Process:	organ growth [IGI] insulin secretion [IGI] post-embryonic development [IGI][IMP] palate development [IGI][IMP] anterior/posterior pattern formation [IGI][IMP] mesoderm development [IGI] pattern specification process [IGI] odontogenesis of dentine-containing tooth [IGI][IMP] transmembrane receptor protein serine/threonine kinase signaling pathway [IEA] protein amino acid phosphorylation [IEA] embryonic foregut morphogenesis [IMP] skeletal system morphogenesis [IGI][IMP] determination of left/right symmetry [IGI][IMP] activin receptor signaling pathway [IEA] heart development [IGI][IMP] response to glucose stimulus [IGI] skeletal system development [IGI][IMP] kidney development [IGI][IMP] gastrulation with mouth forming second [IGI] activation of protein kinase activity [IDA] lung development [IGI] pancreas development [IGI]
Molecular Function:	growth factor binding [IMP][IPI] protein kinase activity [IEA] transforming growth factor beta receptor activity [IEA] receptor activity [IEA] protein serine/threonine kinase activity [IDA] transmembrane receptor protein serine/threonine kinase activity [IEA] nucleotide binding [IEA] [NOT]transforming growth factor beta binding [IDA] ATP binding [IEA] inhibin beta-B binding [UNKNOWN] receptor signaling protein serine/threonine kinase activity [IEA] inhibin beta-A binding [UNKNOWN] protein binding [IPI] protein serine/threonine/tyrosine kinase activity [IDA] activin binding [UNKNOWN][IDA][IPI] metal ion binding [IEA] activin receptor activity [IEA] transferase activity [IEA] kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAPWAALAL LWGSLCAGSG RGEAETRECI YYNANWELER TNQSGLERCE GEQDKRLHCY  60
   61 ASWRNSSGTI ELVKKGCWLD DFNCYDRQEC VATEENPQVY FCCCEGNFCN ERFTHLPEPG 120
  121 GPEVTYEPPP TAPTLLTVLA YSLLPIGGLS LIVLLAFWMY RHRKPPYGHV DIHEVRQCQR 180
  181 WAGRRDGCAD SFKPLPFQDP GPPPPSPLVG LKPLQLLEIK ARGRFGCVWK AQLMNDFVAV 240
  241 KIFPLQDKQS WQSEREIFST PGMKHENLLQ FIAAEKRGSN LEVELWLITA FHDKGSLTDY 300
  301 LKGNIITWNE LCHVAETMSR GLSYLHEDVP WCRGEGHKPS IAHRDFKSKN VLLKSDLTAV 360
  361 LADFGLAVRF EPGKPPGDTH GQVGTRRYMA PEVLEGAINF QRDAFLRIDM YAMGLVLWEL 420
  421 VSRCKAADGP VDEYMLPFEE EIGQHPSLEE LQEVVVHKKM RPTIKDHWLK HPGLAQLCVT 480
  481 IEECWDHDAE ARLSAGCVEE RVSLIRRSVN GTTSDCLVSL VTSVTNVDLL PKESSI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: AVR2B_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: