Protein Overview: TBL1R_MOUSE

General Information:
Name(s) found:	TBL1R_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|74200166\|dbj\|BAE22898.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|46577466\|sp\|Q8BHJ5.1\|TBL1R_MOUSE RecName: Full=F-box-like/WD repeat-containing protein TBL1XR1; AltName: Full=Transducin beta-like 1X-related protein 1; AltName: Full=Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; AltName: Full=TBL1-related [NCBI NR] gi\|31543001\|ref\|NP_109657.2\| IRA1 protein [Mus musculus] [NCBI NR] gi\|26329005\|dbj\|BAC28241.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|26325544\|dbj\|BAC26526.1\| unnamed protein product [Mus musculus] [NCBI NR] gi\|148702956\|gb\|EDL34903.1\| transducin (beta)-like 1X-linked receptor 1, isoform CRA_a [Mus musculus] [NCBI NR] gi\|148702955\|gb\|EDL34902.1\| transducin (beta)-like 1X-linked receptor 1, isoform CRA_a [Mus musculus] [NCBI NR] (Q8BHJ5) F-box-like/WD-repeat protein TBLR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) [Swiss-Prot] F-box-like/WD repeat-containing protein TBL1XR1 OS=Mus musculus GN=Tbl1xr1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):3-21877036 IRA1 protein [hmr_yeast5_DM3-1_pombe.fasta] IRA1 protein [HMR_022704-rand.fasta] F-box-like/WD-repeat protein TBLR1 [ipi.MOUSE.v3.06.fasta] IRA1 protein [Mus musculus]gi\|46577466\|sp\|Q8BHJ5\|TBLR_MOUSE F-box-like/WD-repeat protein TBLR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1)gi\|26329005\|dbj\|BAC28241.1\| unnamed protein product [Mus musculus]gi\|26325 [nrdb_11152004_Chlamydomonas] Tax_Id=10090 F-box-like/WD-repeat protein TBL1XR1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] IRA1 protein [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 F-box-like/WD-repeat protein TBLR1 [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] F-box-like/WD repeat-containing protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] transducin (beta)-like 1X-linked receptor 1, isoform CRA_a [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 F-BOX-LIKE/WD-REPEAT PROTEIN TBLR1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Tbl1xr1 F-box-like/WD repeat-containing protein TBL1XR1 [mouse-ipi-250309-contam.fasta] F-box-like/WD repeat protein TBL1XR1 (Transducin beta-like 1X-related protein 1) (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) [nr-271106-contam.fasta] Tax_Id=10090 Gene_Symbol=Tbl1xr1 F-box-like/WD repeat protein TBL1XR1 [zeeyong.fasta] Tax_Id=10090 Gene_Symbol=Tbl1xr1 F-box-like/WD repeat-containing protein TBL1XR1 ENSMUSG00000027630 IPI00308283 IPI00551395 [IPIxENS.MOUSE_plus_REVERSE.fasta] PREDICTED: similar to IRA1 protein isoform 1 [Mus musculus] [mouse-040506-contam.fasta] PREDICTED: similar to IRA1 protein isoform 2 [Mus musculus] [mouse-040506-contam.fasta] PREDICTED: similar to IRA1 protein isoform 3 [Mus musculus] [mouse-040506-contam.fasta] F-box-like/WD repeat-containing protein TBL1XR1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00308283.1\|SWISS-PROT:Q8BHJ5\|ENSEMBL:ENSMUSP00000067164;ENSMUSP00000067277\|REFSEQ:NP_109657 Tax_Id=10090 Gene_Symbol=Tbl1xr1 F-box-like/WD repeat-containing protein TBL1XR1 [ipi.MOUSE.fasta.20090209] F-box-like/WD repeat-containing protein TBL1XR1 OS=Mus musculus GN=Tbl1xr1 [011711_HMR.fasta] F-box-like/WD repeat-containing protein TBL1XR1 OS=Mus musculus GN=Tbl1xr1 PE=2 SV=1 [UniProt_mouse_sprotvarsplic_11-08-2010_reversed.fasta] sp\|Q8BHJ5\|TBL1R_MOUSE F-box-like/WD repeat-containing protein TBL1XR1 OS=Mus musculus GN=Tbl1xr1 PE=2 SV=1 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	514 amino acids
Gene Ontology:
Cellular Component:	nucleus [IC]
Biological Process:	chromatin modification [IEA] proteasomal ubiquitin-dependent protein catabolic process [IMP] transcription [IEA] negative regulation of transcription, DNA-dependent [IMP] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [IMP]
Molecular Function:	DNA binding [IDA] protein binding [IPI] transcription corepressor activity [IMP] promoter binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSISSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GALVPPAALI SIIQKGLQYV  60
   61 EAEVSINEDG TLFDGRPIES LSLIDAVMPD VVQTRQQAYR DKLAQQHAAA AAAAAAATNQ 120
  121 QGSAKNGENT ANGEENGAHT IANNHTDMME VDGDVEIPSN KAVVLRGHES EVFICAWNPV 180
  181 SDLLASGSGD STARIWNLSE NSTSGPTQLV LRHCIREGGQ DVPSNKDVTS LDWNSEGTLL 240
  241 ATGSYDGFAR IWTKDGNLAS TLGQHKGPIF ALKWNKKGNF ILSAGVDKTT IIWDAHTGEA 300
  301 KQQFPFHSAP ALDVDWQSNN TFASCSTDMC IHVCKLGQDR PIKTFQGHTN EVNAIKWDPT 360
  361 GNLLASCSDD MTLKIWSMKQ DNCVHDLQAH NKEIYTIKWS PTGPGTNNPN ANLMLASASF 420
  421 DSTVRLWDVD RGICIHTLTK HQEPVYSVAF SPDGRYLASG SFDKCVHIWN TQTGALVHSY 480
  481 RGTGGIFEVC WNAAGDKVGA SASDGSVCVL DLRK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: TBL1R_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: