Protein Overview: GPX42_RAT

General Information:
Name(s) found:	GPX42_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|90903229\|ref\|NP_001034938.1\| glutathione peroxidase 4 isoform B precursor [Rattus norvegicus] [NCBI NR] gi\|172045826\|sp\|Q91XR8.3\|GPX42_RAT RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, nuclear; AltName: Full=GPX-4 [NCBI NR] Phospholipid hydroperoxide glutathione peroxidase, nuclear OS=Rattus norvegicus GN=Gpx4 PE=1 SV=3 [Swiss-Prot] Phospholipid hydroperoxide glutathione peroxidase, nuclear (GPX-4) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutathione peroxidase 4 isoform B precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Isoform Nuclear of Phospholipid hydroperoxide glutathione peroxidase, nuclear OS=Rattus norvegicus GN=Gpx4 [011711_HMR.fasta] Phospholipid hydroperoxide glutathione peroxidase, nuclear OS=Rattus norvegicus GN=Gpx4 PE=2 SV=3 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	253 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [UNKNOWN][IEA] nucleus [UNKNOWN][IEA][ISS] soluble fraction [IDA] cytoplasm [IEA] mitochondrion [UNKNOWN][IEA] cytosol [UNKNOWN][IEA] mitochondrial inner membrane [UNKNOWN][IEA]
Biological Process:	response to oxidative stress [IEA] multicellular organismal development [IEA] glutathione metabolic process [IDA] spermatogenesis [UNKNOWN][IEA][ISS] response to estradiol stimulus [IEP] regulation of inflammatory response [IMP] oxidation reduction [IEA] chromatin organization [UNKNOWN][IEA][ISS] aging [IEP] hydrogen peroxide catabolic process [IDA]
Molecular Function:	phospholipid-hydroperoxide glutathione peroxidase activity [IDA] glutathione peroxidase activity [UNKNOWN][IDA][ISS] selenium binding [IDA][IMP] glutathione binding [IDA] oxidoreductase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRAAARKRG RCRQRGRSPG GRRRREPGRQ SPRKRPGPRR RRARARRRRR ARPRRMEPIP  60
   61 EPFNPRPLLQ DLPQTSNSHE FLGLCASRDD WRCARSMHEF AAKDIDGHMV CLDKYRGCVC 120
  121 IVTNVASQUG KTDVNYTQLV DLHARYAECG LRILAFPCNQ FGRQEPGSNQ EIKEFAAGYN 180
  181 VRFDMYSKIC VNGDDAHPLW KWMKVQPKGR GMLGNAIKWN FTKFLIDKNG CVVKRYGPME 240
  241 EPQVIEKDLP CYL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: GPX42_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: