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Protein Overview: VAPB

General Information:
Name(s) found: VAPB [HGNC (HUGO)]
Description(s) found:
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  • pir||JG0186 vesicle-associated membrane protein-associated protein B - human [NCBI NR]
  • gi|4759302|ref|NP_004729.1| VAMP-associated protein B/C [Homo sapiens] [NCBI NR]
  • gi|4240458|gb|AAD13577.1| VAMP-associated protein B [Homo sapiens] [NCBI NR]
  • gi|37182052|gb|AAQ88829.1| VAPB [Homo sapiens] [NCBI NR]
  • gi|32879965|gb|AAP88813.1| VAMP (vesicle-associated membrane protein)-associated protein B and C [Homo sapiens] [NCBI NR]
  • gi|24638339|sp|O95292.3|VAPB_HUMAN RecName: Full=Vesicle-associated membrane protein-associated protein B/C; Short=VAMP-associated protein B/C; AltName: Full=VAMP-B/VAMP-C; Short=VAP-B/VAP-C [NCBI NR]
  • gi|193785739|dbj|BAG51174.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|12804585|gb|AAH01712.1| VAPB protein [Homo sapiens] [NCBI NR]
  • gi|119595901|gb|EAW75495.1| VAMP (vesicle-associated membrane protein)-associated protein B and C, isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|119595900|gb|EAW75494.1| VAMP (vesicle-associated membrane protein)-associated protein B and C, isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|11125137|emb|CAC15021.1| VAMP (vesicle-associated membrane protein)-associated protein B and C [Homo sapiens] [NCBI NR]
  • VAMP (vesicle-associated membrane protein)-associated protein B and C [HGNC (HUGO)]
  • Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens GN=VAPB PE=1 SV=3 [Swiss-Prot]
  • Splice isoform 1 of O95292 [hmr_yeast5_DM3-1_pombe.fasta]
  • VAMP-associated protein B/C; VAMP-associated protein C; VAMP-associated protein B; VAMP-associated 33 kDa protein [HMR_022704.fasta]
  • VAMP-associated protein B/C; VAMP-associated protein C; VAMP-associated 33 kDa protein; VAMP-associated protein B [Human2242005.fasta]
  • VAPB [Homo sapiens]gi|4759302|ref|NP_004729.1| VAMP-associated protein B/C [Homo sapiens]gi|32879965|gb|AAP88813.1| VAMP (vesicle-associated membrane protein)-associated protein B and C [Homo sapiens]gi|11125137|emb|CAC15021.1| dJ1018E9.1 (VAMP (vesicl [nrdb_11152004_Chlamydomonas]
  • Vesicle-associated membrane protein-associated protein B/C (VAMP-associated protein B/C) (VAMP-B/VAMP-C) (VAP-B/VAP-C) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 VAMP-associated protein B/C [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_004738) VAMP (vesicle-associated membrane protein)-associated protein B and C; VAMP-associated protein C; VAMP-associated protein B; VAMP-associated 33 kDa protein [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • VAMP-associated protein B/C [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 VAMP (Vesicle-associated membrane protein)-associated protein B and C [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Vesicle-associated membrane protein-associated protein B/C [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • VAMP-associated protein B/C; VAMP-associated protein C; VAMP-associated 33 kDa protein; VAMP-associated protein B [Homo sapiens] [HumanGallus06162005.fasta]
  • VAMP-associated protein B/C; VAMP-associated protein C; VAMP-associated protein B; VAMP-associated 33 kDa protein [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • VAMP (vesicle-associated membrane protein)-associated protein B and C [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • VAMP (vesicle-associated membrane protein)-associated protein B and C, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • VAPB protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • VAPB [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • VAMP-associated protein B [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN B/C [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Vesicle-associated membrane protein-associated protein B/C; Short=VAMP-associated protein B/C; AltName: Full=VAMP-B/VAMP-C; Short=VAP-B/VAP-C [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=VAPB Isoform 1 of Vesicle-associated membrane protein-associated protein B/C [human-ipi-250309-contam.fasta]
  • IPI:IPI00006211.4|SWISS-PROT:O95292-1|TREMBL:B3KVU7;Q53XM7|ENSEMBL:ENSP00000265619|REFSEQ:NP_004729|H-INV:HIT000030595|VEGA:OTTHUMP00000031393 Tax_Id=9606 Gene_Symbol=VAPB Isoform 1 of Vesicle-associated membrane protein-associated protein B/C [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Isoform 1 of Vesicle-associated membrane protein-associated protein B/C [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=VAPB Isoform 1 of Vesicle-associated membrane protein-associated protein B/C ENSG00000124164 IPI00748221 IPI00216174 IPI00006211 IPI00443658 IPI00444581 [drosphohumanreversed.fasta]
  • vesicle-associated membrane protein-associated protein B/C [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • O95292;A2A2F2;O95293;Q9P0H0; RecName: Full=Vesicle-associated membrane protein-associated protein B/C; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens GN=VAPB [011711_HMR.fasta]
  • IPI:IPI00006211.4|SWISS-PROT:O95292-1|TREMBL:B3KVU7;Q53XM7|ENSEMBL:ENSP00000417175|REFSEQ:NP_004729|H-INV:HIT000030595|VEGA:OTTHUMP00000031393 Tax_Id=9606 Gene_Symbol=VAPB Isoform 1 of Vesicle-associated membrane protein-associated protein B/C [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=VAPB Synonyms=ALS8|VAMP-B|VAP-B vesicle-associated membrane protein-associated protein B/C [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Vesicle-associated membrane protein-associated protein B/C GN=VAPB [Doctor+uniprot-HUMAN-120911.fasta]
  • VAMP (Vesicle-associated membrane protein)-associated protein B and C OS=Homo sapiens GN=VAPB PE=2 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 243 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKVEQVLSL EPQHELKFRG PFTDVVTTNL KLGNPTDRNV CFKVKTTAPR RYCVRPNSGI  60
   61 IDAGASINVS VMLQPFDYDP NEKSKHKFMV QSMFAPTDTS DMEAVWKEAK PEDLMDSKLR 120
  121 CVFELPAEND KPHDVEINKI ISTTASKTET PIVSKSLSSS LDDTEVKKVM EECKRLQGEV 180
  181 QRLREENKQF KEEDGLRMRK TVQSNSPISA LAPTGKEEGL STRLLALVVL FFIVGVIIGK 240
  241 IAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run gi|14317902, gi|... No Comments Cheeseman, I.M., et al. (2004)
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] PSI-BLAST 40.30103 Solution structure of the MSP domain of mouse VAMP-associated proteinA
    2 View Details [154..243] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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