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Protein Overview: NUP1

General Information:
Name(s) found: NUP1 / YOR098C [SGD]
Description(s) found:
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  • gi|6324672|ref|NP_014741.1| Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc2 [NCBI NR]
  • gi|172056|gb|AAA34822.1| nucleoporin (NUP1) (put.); putative [NCBI NR]
  • gi|1420275|emb|CAA99295.1| NUP1 [Saccharomyces cerevisiae] [NCBI NR]
  • gi|128907|sp|P20676.1|NUP1_YEAST RecName: Full=Nucleoporin NUP1; AltName: Full=Nuclear pore protein NUP1 [NCBI NR]
  • gi|1164945|emb|CAA64020.1| YOR3182c [Saccharomyces cerevisiae] [NCBI NR]
  • pir||A35622 nuclear pore protein NUP1 - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Nucleoporin NUP1 OS=Saccharomyces cerevisiae GN=NUP1 PE=1 SV=1 [Swiss-Prot]
  • NUP1 Nuclear pore protein [mips]
  • Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate [SGD]
  • (P20676) Nucleoporin NUP1 (Nuclear pore protein NUP1) [4932.FASTACCERV.txt]
  • Chr XV from 511178-507948, reverse complement [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XV from 507947-511177, reverse complement [yeastorf3.fasta]
  • Chr XV from 507948-511178, reverse complement [yeastorf4.fasta]
  • NUP1, Chr XV from 507947-511177, reverse complement [yeast_orfs2]
  • NUP1 SGDID:S0005624, Chr XV from 511178-507948, reverse complement, Verified ORF [yeastflysequest.fasta]
  • Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate [Saccharomyces [nrdb_11152004_Chlamydomonas]
  • NUP1 SGDID:S000005624, Chr XV from 511178-507948, reverse complement, Verified ORF, "Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-c [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • NUP1 SGDID:S000005624, Chr XV from 511179-507949, reverse complement, Verified ORF, "Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-c [yeast-contam.fasta]
  • Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate; Nup1p [Sacchar [nr-271106-contam.fasta]
  • Nucleoporin NUP1 (Nuclear pore protein NUP1) [nr-271106-contam.fasta]
  • YOR3182c [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • NUP1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • nucleoporin (NUP1) (put.); putative [nr-271106-contam.fasta]
  • NUP1 SGDID:S000005624, Chr XV from 511179-507949, reverse complement, Verified ORF, "Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • Nucleoporin NUP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUP1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • NUP1 SGDID:S000005624, Chr XV from 511178-507948, Genome Release 64-1-1, reverse complement, Verified ORF, "Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate" [yeast-030211-contam.fasta]
  • NUP1 SGDID:S000005624, Chr XV from 511178-507948, Genome Release 64-2-1, reverse complement, Verified ORF, "FG-nucleoporin component of central core of the nuclear pore complex; contributes directly to nucleocytoplasmic transport and maintenance of thenuclear pore complex (NPC) permeability barrier; possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; both NUP1 and NUP60 are homologous to human NUP153" [20141208_orf_trans.fasta]
  • YOR098C SGDID:S000005624, Chr XV from 511178-507948, Genome Release 64-1-1, reverse complement, Verified ORF, "Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 1076 amino acids

    Gene Ontology:
    Cellular Component: nuclear pore [IDALink to PubMed article]
    Biological Process: protein export from nucleus [TASLink to PubMed article]
    ribosomal protein import into nucleus [TASLink to PubMed article]
    mRNA export from nucleus [IMPLink to PubMed article]
    rRNA export from nucleus [TASLink to PubMed article]
    nuclear envelope organization [IMPLink to PubMed article]
    RNA export from nucleus [IMPLink to PubMed article]
    nuclear pore organization [TASLink to PubMed article]
    snRNP protein import into nucleus [TASLink to PubMed article]
    mRNA-binding (hnRNP) protein import into nucleus [TASLink to PubMed article]
    snRNA export from nucleus [TASLink to PubMed article]
    protein import into nucleus [IMPLink to PubMed articleLink to PubMed article]
    tRNA export from nucleus [TASLink to PubMed article]
    NLS-bearing substrate import into nucleus [TASLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    structural molecule activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSNTSSVMS SPRVEKRSFS STLKSFFTNP NKKRPSSKKV FSSNLSYANH LEESDVEDTL  60
   61 HVNKRKRVSG TSQHSDSLTQ NNNNAPIIIY GTENTERPPL LPILPIQRLR LLREKQRVRN 120
  121 MRELGLIQST EFPSITSSVI LGSQSKSDEG GSYLCTSSTP SPIKNGSCTR QLAGKSGEDT 180
  181 NVGLPILKSL KNRSNRKRFH SQSKGTVWSA NFEYDLSEYD AIQKKDNKDK EGNAGGDQKT 240
  241 SENRNNIKSS ISNGNLATGP NLTSEIEDLR ADINSNRLSN PQKNLLLKGP ASTVAKTAPI 300
  301 QESFVPNSER SGTPTLKKNI EPKKDKESIV LPTVGFDFIK DNETPSKKTS PKATSSAGAV 360
  361 FKSSVEMGKT DKSTKTAEAP TLSFNFSQKA NKTKAVDNTV PSTTLFNFGG KSDTVTSASQ 420
  421 PFKFGKTSEK SENHTESDAP PKSTAPIFSF GKQEENGDEG DDENEPKRKR RLPVSEDTNT 480
  481 KPLFDFGKTG DQKETKKGES EKDASGKPSF VFGASDKQAE GTPLFTFGKK ADVTSNIDSS 540
  541 AQFTFGKAAT AKETHTKPSE TPATIVKKPT FTFGQSTSEN KISEGSAKPT FSFSKSEEER 600
  601 KSSPISNEAA KPSFSFPGKP VDVQAPTDDK TLKPTFSFTE PAQKDSSVVS EPKKPSFTFA 660
  661 SSKTSQPKPL FSFGKSDAAK EPPGSNTSFS FTKPPANETD KRPTPPSFTF GGSTTNNTTT 720
  721 TSTKPSFSFG APESMKSTAS TAAANTEKLS NGFSFTKFNH NKEKSNSPTS FFDGSASSTP 780
  781 IPVLGKPTDA TGNTTSKSAF SFGTANTNGT NASANSTSFS FNAPATGNGT TTTSNTSGTN 840
  841 IAGTFNVGKP DQSIASGNTN GAGSAFGFSS SGTAATGAAS NQSSFNFGNN GAGGLNPFTS 900
  901 ATSSTNANAG LFNKPPSTNA QNVNVPSAFN FTGNNSTPGG GSVFNMNGNT NANTVFAGSN 960
  961 NQPHQSQTPS FNTNSSFTPS TVPNINFSGL NGGITNTATN ALRPSDIFGA NAASGSNSNV1020
 1021 TNPSSIFGGA GGVPTTSFGQ PQSAPNQMGM GTNNGMSMGG GVMANRKIAR MRHSKR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) KAP95 NUP1
    View Details (MIPS) Mewes HW, et al. (2004) GLE2 NOP14 NUP1 NUP100 NUP116 NUP133 NUP157 NUP159 NUP170 NUP188 NUP2 NUP42 POM152
    View Details Krogan NJ, et al. (2006) CBC2 KAP95 NUP1 NUP2 NUP60 OGG1 PCT1 RAD53 SRP1 STO1 ULP1 URB2 YRA2
    View Details Ho Y, et al. (2002) DIS3 EAF3 FIP1 HAS1 HPR1 KAP95 MES1 MFT1 NAM8 NOP6 NUP1 NUP2 NUP60 PAP1 PCT1 REB1 RNT1 RRP4 RRP43 RRP6 RTT103 SIF2 SIN3 SNU56 SRP1 STO1 THO2 TRA1 UME1 YPR090W
    View Details Qiu et al. (2008) ASM4 DBP5 GLE2 KAP122 KAP123 MEX67 MTR2 NDC1 NIC96 NSP1 NUP1 NUP100 NUP116 NUP133 NUP145 NUP157 NUP159 NUP170 NUP188 NUP192 NUP2 NUP42 NUP49 NUP53 NUP57 NUP60 NUP82 NUP84 NUP85 POM152 SEC13 SUS1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run RLF2 phosphorylation data - cascade search Green EM, et al (2005)
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen NUP1 SOR1 2 Unpublished Fields Lab Data
    View Screen NUP1 RPO26 2 Unpublished Fields Lab Data
    View Screen NUP1 SPT23 2 Unpublished Fields Lab Data
    View Screen NUP1 YKL061W 2 Unpublished Fields Lab Data
    View Screen NUP1 OAF3 2 Unpublished Fields Lab Data
    View Screen NUP1 DNM1 2 Unpublished Fields Lab Data
    View Screen NUP1 ADE13 2 Unpublished Fields Lab Data
    View Screen NUP1 HOF1 2 Unpublished Fields Lab Data
    View Screen NUP1 SNZ1 2 Unpublished Fields Lab Data
    View Screen NUP1 PEX22 2 Unpublished Fields Lab Data
    View Screen NUP1 ATG16 2 Unpublished Fields Lab Data
    View Screen NUP1 SHP1 2 Unpublished Fields Lab Data
    View Screen NUP1 URA10 2 Unpublished Fields Lab Data
    View Screen NUP1 TPS1 2 Unpublished Fields Lab Data
    View Screen NUP1 NBA1 2 Unpublished Fields Lab Data
    View Screen NUP1 CSM1 2 Unpublished Fields Lab Data
    View Screen NUP1 WTM2 2 Unpublished Fields Lab Data
    View Screen NUP1 YDR132C 2 Unpublished Fields Lab Data
    View Screen NUP1 MYO2 2 Unpublished Fields Lab Data
    View Screen NUP1 PNC1 2 Unpublished Fields Lab Data
    View Screen NUP1 MRS6 2 Unpublished Fields Lab Data
    View Screen NUP1 DYS1 2 Unpublished Fields Lab Data
    View Screen NUP1 DIG1 2 Unpublished Fields Lab Data
    View Screen NUP1 ARP1 2 Unpublished Fields Lab Data
    View Screen NUP1 YPR172W 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data NUP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..276] MSA 1.150997 View MSA. No confident structure predictions are available.
    2 View Details [277..1076] MSA 10.232997 View MSA. No confident structure predictions are available.
    3 View Details [389..632] deduced N/A No confident structure predictions are available.
    4 View Details [633..746] MSA 2.214988 View MSA. No confident structure predictions are available.
    5 View Details [747..892] deduced N/A No confident structure predictions are available.
    6 View Details [893..1076] MSA 2.19299 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.48

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle