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Protein Overview: ALG9

General Information:
Name(s) found: ALG9 / YNL219C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Mannosyltransferase, involved in N-linked glycosylation; catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides; mutation of the human ortholog causes type 1 congenital disorders of glycosylation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 555 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: protein amino acid glycosylation [IMPLink to PubMed article]
    dolichol-linked oligosaccharide biosynthetic process [TASLink to PubMed article]
    Molecular Function: mannosyltransferase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNCKAVTISL LLLLFLTRVY IQPTFSLISD CDETFNYWEP LNLLVRGFGK QTWEYSPEYS  60
   61 IRSWAFLLPF YCILYPVNKF TDLESHWNFF ITRACLGFFS FIMEFKLHRE IAGSLALQIA 120
  121 NIWIIFQLFN PGWFHASVEL LPSAVAMLLY VGATRHSLRY LSTGSTSNFT KSLAYNFLAS 180
  181 ILGWPFVLIL SLPLCLHYLF NHRIISTIRT AFDCCLIFSL TAFAVIVTDS IFYGKLAPVS 240
  241 WNILFYNVIN ASEESGPNIF GVEPWYYYPL NLLLNFPLPV LVLAILGIFH LRLWPLWASL 300
  301 FTWIAVFTQQ PHKEERFLYP IYGLITLSAS IAFYKVLNLF NRKPILKKGI KLSVLLIVAG 360
  361 QAMSRIVALV NNYTAPIAVY EQFSSLNQGG VKAPVVNVCT GREWYHFPSS FLLPDNHRLK 420
  421 FVKSGFDGLL PGDFPESGSI FKKIRTLPKG MNNKNIYDTG KEWPITRCDY FIDIVAPINL 480
  481 TKDVFNPLHL MDNWNKLACA AFIDGENSKI LGRAFYVPEP INRIMQIVLP KQWNQVYGVR 540
  541 YIDYCLFEKP TETTN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) ALG12 ALG2 ALG8 ALG9 PMT2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen HMT1 ALG9 1 Unpublished Fields Lab Data
    View Screen UBC7 ALG9 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ALG9 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..412] MSA 8.034964 View MSA. No confident structure predictions are available.
    2 View Details [413..555] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle