General Information: |
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Name(s) found: |
SIR2_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 350 amino acids |
Gene Ontology: |
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Cellular Component: |
cytoskeleton
[IEA]
cytoplasm [UNKNOWN][ISS] cellular_component [ND] microtubule [UNKNOWN][IEA] |
Biological Process: |
cell division
[IEA]
biological_process [ND] negative regulation of transcription [UNKNOWN] protein amino acid deacetylation [UNKNOWN][IEA] mitosis [IEA] chromatin silencing [IEA] regulation of transcription [IEA] cell cycle [IEA] negative regulation of striated muscle tissue development [UNKNOWN] |
Molecular Function: |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
[IEA]
zinc ion binding [UNKNOWN][IEA] histone acetyltransferase binding [UNKNOWN] histone deacetylase binding [UNKNOWN] tubulin deacetylase activity [UNKNOWN] transcription factor binding [UNKNOWN] molecular_function [ND] protein binding [UNKNOWN] ubiquitin binding [UNKNOWN] metal ion binding [IEA] NAD-dependent histone deacetylase activity [UNKNOWN] protein deacetylase activity [UNKNOWN] NAD binding [IEA] hydrolase activity [IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MDFLRNLFTQ TLGLGSQKER LLDELTLEGV TRYMQSERCR RVICLVGAGI STSAGIPDFR 60 61 SPSTGLYANL EKYHLPYPEA IFEISYFKKH PEPFFALAKE LYPGQFKPTI CHYFIRLLKE 120 121 KGLLLRCYTQ NIDTLERVAG LEPQDLVEAH GTFYTSHCVN TSCGKEYTMS WMKEKIFSEA 180 181 TPKCEKCQNV VKPDIVFFGE NLPPRFFSCM QSDFSKVDLL IIMGTSLQVQ PFASLISKAP 240 241 LATPRLLINK EKTGQTDPFL GMMMGLGGGM DFDSKKAYRD VAWLGDCDQG CLALADLLGW 300 301 KELEDLVRRE HANIDAQSGS QASNPSATVS PRKSPPPAKE AARTKEKEEH |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.75 |
Source: Reynolds et al. (2008)