Protein Overview: trol-PF

General Information:
Name(s) found:	trol-PF / FBpp0070435 [FlyBase]
Description(s) found: Found 11 descriptions. SHOW ALL	The gene terribly reduced optic lobes is referred to in FlyBase by the symbol Dmel\trol (CG33950, FBgn0261451). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:2365016..2439423. It has the cytological map location 3A1-3A4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: maintenance of epithelial cell apical/basal polarity. 171 alleles are reported. The phenotypes of these alleles are annotated with: female reproductive system; eye; dorsal mesothoracic disc; neuroblast; brain; dorsal metathoracic disc; larval brain; larval optic lobe; thoracic neuroblast; larval central nervous system. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	4629 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IDA] basement membrane [ISS] extracellular matrix [IEA] proteinaceous extracellular matrix [NAS]
Biological Process:	maintenance of epithelial cell apical/basal polarity [IMP] asymmetric neuroblast division [NAS] cell adhesion [IEA]
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMGSPGSQAS AIATSVGIRS GRRGQAGGSL LLRLLAVTFV LAACHAPLLT NAKQISNLGD  60
   61 DQDFMLADDE SLQGINDSEW QLMGDDIDDG LLDDVDETLK PMETKSEEED LPTGNWFSQS 120
  121 VHRVRRSINR LFGSDDNQER GRRQQRERSQ RNRDAINRQK ELRRRQKEDH NRWKQMRMER 180
  181 QLEKQRLVKR TNHVVFNRAT DPRKRASDLY DENEASGYHE EDTTLYRTYF VVNEPYDNEY 240
  241 RDRESVQFQN LQKLLDDDLR NFFHSNYEGN DDEEQEIRST LERVEIELPT SVNDFGSKLQ 300
  301 QQLNVYNRIE NLSAATDGVF SFTESSDIEE EAIDVTLPQE EVEGSGSDDS SCRGDATFTC 360
  361 PRSGKTICDE MRCDREIQCP DGEDEEYCNY PNVCTEDQFK CDDKCLELKK RCDGSIDCLD 420
  421 QTDEAGCINA PEPEPEPEPE PEPEPESEPE AEPEPEPEPE PESEPEQEPE PQVPEANECQ 480
  481 ANEFRCNNGD CIDARKRCNN VSDCSEGEDE NEECPAACSG MEYQCRDGTR CISVSQQCDG 540
  541 HSDCSDGDDE EHCDGIVPKL RYTCPKGKFT CRDLSCISIV HRCDGRADCP NDRSDEEGCP 600
  601 CLYDKWQCDD GTCIAKELLC NGNIDCPEDI SDERYCEGGY DSEECRFDEF HCGTGECIPM 660
  661 RQVCDNIYDC NDYSDEVNCV EGEEEDRVGI PIGHQPWRPA SKHDDWLHEM DTSEYQVYQP 720
  721 SNVYEKANSQ NPCASNQFRC TTSNVCIPLH LRCDGFYHCN DMSDEKSCEQ YQRHTTTRRP 780
  781 LTLATPTSRI TTQGPGLLER RNTTTATEAS RWPWATKTTT IATTTSNPIT TVGVANSPPQ 840
  841 TCLENIEFAC HNRDCISIES VCDGIPDCGR NEDEDDALCK CSGDKYKCQR GGGCIPKSQV 900
  901 CDGKPQCHDR SDESACHLHG RLNKTRLGVK CLESQYQCGD GSCISGYKRC NGIHDCADAS 960
  961 DEYNCIYDYE DTYDTDPNNN PLNECDILEF ECDYSQCLPL EKKCDGYADC EDMSDELECQ1020
 1021 SYTDHCLESE FECDSYCLPR DQLCNGIPNC QDGSDERNCT FCREDAYLCN TGECVADNQR1080
 1081 CNGIADCADG SDERHCARIY CPPNKLACNG TCVSRRIKCD GIRDCLDGYD EMYCPETNNH1140
 1141 YPTQNVNVIR PKLGPNPIPK SCRPHEWQCA NLECIDSSLQ CNEIKDCSDG SDEELSVCFG1200
 1201 TATTRLKPSD CSPEQFYCDE SCYNRSVRCN GHVDCSDGSD EVGCSLPCPQ HQCPSGRCYT1260
 1261 ESERCDRHRH CEDGSDEANC TAILCKDNEF LCFDRQFCIN ATQQCDGYYD CRDFSDEQNC1320
 1321 IGCYANQFRC NNGDCVSGSA PCNGYSECSD HSDELNCGGT QECLPNQFRC NSGQCVSSSV1380
 1381 RCNGRTDCQD SSDEQNCGHR HTEVSQGLET TGVFTTSTTS TTAMTPLRII CPPTSFKCEN1440
 1441 GPCISLGLKC NGRVDCPYDG SDEADCGQIS NDIDPADSND RRPNQLNLKT YPDSQIIKES1500
 1501 REVIFRCRDE GPARAKVKWS RPGGRPLPPG FTDRNGRLEI PNIRVEDAGT YVCEAVGYAS1560
 1561 YIPGQQVTVN LNVERSWGEN KYEEIRSNRI RYGTVPHIDL EFFGLDNDVG SRPESACTEY1620
 1621 QATCMNGECI DKSSICDGNP DCSDASDEQS CSLGLKCQPN QFMCSNSKCV DRTWRCDGEN1680
 1681 DCGDNSDETS CDPEPSGAPC RYNEFQCRSG HCIPKSFQCD NVPDCTDGTD EVGCMAPLPI1740
 1741 RPPPQSVSLL EYEVLELTCV ATGTPTPTIV WRLNWGHVPD KCESKSYGGT GTLRCPDMRP1800
 1801 QDSGAYSCEI INTRGTHFVN PDTIVTVRPV RTDVCEAGFF NMLARKAEEC VQCFCFGVAK1860
 1861 ACDSANLFTY AIHPPILSHR VVSVELSPLR QIVINEAAPG QDLLTLLHGV QFRATNVHFS1920
 1921 GRETPYLALP ADYMGNQLKS YGGNLRYEVN YRGSGRPVNG PDVIITGNRF TLTYRVRTQP1980
 1981 GQNNRVSIPF VPGGWQKPDG RKASREEIMM ILANVDNILI RLGYLDSTAR EVDLINIALD2040
 2041 SAGTADKGLG SASLVEKCQC PPGYVGDSCE SCASGYVRQP GGPWLGHCVP FIPDSCPSGT2100
 2101 YGDPRRGVPC KECPCPLTGS NNFASGCQQS PDGDVVCRCN EGYTGRRCEQ CAAGYQGNPL2160
 2161 AAGGICRRIP DTSCNVDGTY SVHSNGTCQC KDSVIGEQCD TCKSKSFHLN SFTYTGCIEC2220
 2221 FCSGVGLDCD SSTWYRDQVT STFGRSRVDH GFVLVTNYMQ PTPDTVPVSM AAEPNALSFI2280
 2281 GSADQSGNTL YWSLPAAFLG NKLSSYGGKL TYTLSYSPLP NGIMSRNSAP DVVIKSGEDL2340
 2341 RLIHYRKSQV VPSVANTYSV EIKESAWQRG DEVVANREHV LMALSDITAI YIKATYTTST2400
 2401 KEASLRQVTL DVATPTNLGT PRAVEVEQCR CPEGYLGLSC EQCAPGYARD PEGGIYLGLC2460
 2461 RPCECNGHSK YCNSDTGDCE ECSDNTEGPS CERCAAGYVG DATRGTIYDC QPDEGYPIPS2520
 2521 PPAPGNQTLE CTAYCQIEGI YDCRGNECLC KRNVIGDQCD QCRPGTYGLS AQNQDGCKEC2580
 2581 YCSGLASQCR SAALYRQLIP VDFILNAPLI TDESGAVQDT ENLIPDISRN MYTYTHTSYL2640
 2641 PKYWSLRGSV LGNQLFSYGG RLSYSLIVES YGNYERGHDI VLIGNGLKLI WSRPDGNENQ2700
 2701 EEYNVRLHED EQWTRQDRES ARPASRSDFM TVLSDLQHIL IRATPRVPTQ STSIGNVILE2760
 2761 SAVTTRTPGA THASDIELCQ CPSGYVGTSC ESCAPLHYRD ASGSCSLCPC DVSNTESCDL2820
 2821 VSGGYVECRC KARWKGDRCR EIDTNDPTDI GTEDPVLTQI IVSIQKPEIT IVPVGGSMTL2880
 2881 SCSGRMRWSN SPVIVNWYKE NSRLPENVEV QGGNLYLYDL QVSDSGVYIC QAVNNETASV2940
 2941 FKDTVSITIT KKDQLSPAEI VNLPSHVTFE EYVNNEIICE VLGNPAPRVT WARVDGHADA3000
 3001 QSTRTYDNRL IFDSPRKSDE GRYRCQAEND QNRDEKYVIV YVQSNPPQPP PQQDRLYITP3060
 3061 EEINGLAGES FQLNCQFTSV ASLRYDWSHN GRSLSSSPAR NVEIRGNTLE VRDASESDSG3120
 3121 VYTCVAYDVR TRRNFTESAR VNIDRREEQP FGNKPIIESL EQNILIIQGE DYSITCEASG3180
 3181 SPYPSIKWAK VHDFMPENVH ISGNVLTIYG ARFENRGVYS CVAENDHGSD LSSTSIDIEP3240
 3241 RERPSVKIVS APLQTFSVGA PASLYCTVEG IPDPTVEWVR VDGQPLSPRH KIQSPGYMVI3300
 3301 DDIQLEDSGD YECRAKNIVG EATGVATITV QEPTLVQIIP DNRDLRLTEG DELSLTCVGS3360
 3361 GVPNPEVEWV NEMALKRDLY SPPSNTAILK IYRVTKADAG IYTCHGKNEA GSDEAHVRVE3420
 3421 VQERRGDIGG VDDDSDRDPI NYNPPQQQNP GIHQPGSNQL LATDIGDNVT LTCDMFQPLN3480
 3481 TRWERVDGAP LPRNAYTIKN RLEIVRVEQQ NLGQYRCNGI GRDGNVKTYF VKELVLMPLP3540
 3541 RIRFYPNIPL TVEAGQNLDV HCQVENVRPE DVHWSTDNNR PLPSSVRIVG SVLRFVSITQ3600
 3601 AAAGEYRCSA FNQYGNRSQI ARVAVKKPAD FHQVPQSQLQ RHREGENIQL QCTVTDQYGV3660
 3661 RAQDNVEFNW FRDDRRPLPN NARTDSQILV LTNLRPEDAG RYICNSYDVD RGQQLPEVSI3720
 3721 DLQVLTATPP PNSPIYLPPQ LPAKSRDYSL KLDDQSSNLR AGESTDVECY SSDDTYTDVV3780
 3781 WERSDGAPLS NNVRQVGNRL VISNVSPSDA GNYVCKCKTD EGDLYTTSYK LEVEDQPHEL3840
 3841 KSSKIVYAKV GANADLQCGA DESRQPTYRW SRQYGQLQAG RSLMNEKLSL DSVQANDAGT3900
 3901 YICTAQYADG ETADFPNILV VTGAIPQFRQ EPRSYMSFPT LPNSSFKFNF ELTFRPENGD3960
 3961 GLLLFNGQTR GSGDYIALSL KDRYAEFRFD FGGKPMLVRA EEPLALNEWH TVRVSRFKRD4020
 4021 GYIQVDEQHP VAFPTLQQIP QLDLIEDLYI GGVPNWELLP ADAVSQQVGF VGCISRLTLQ4080
 4081 GRTVELIREA KYKEGITDCR PCAQGPCQNK GVCLESQTEQ AYTCICQPGW TGRDCAIEGT4140
 4141 QCTPGVCGAG RCENTENDME CLCPLNRSGD RCQYNEILNE HSLNFKGNSF AAYGTPKVTK4200
 4201 VNITLSVRPA SLEDSVILYT AESTLPSGDY LALVLRGGHA ELLINTAARL DPVVVRSAEP4260
 4261 LPLNRWTRIE IRRRLGEGIL RVGDGPERKA KAPGSDRILS LKTHLYVGGY DRSTVKVNRD4320
 4321 VNITKGFDGC ISRLYNFQKP VNLLADIKDA ANIQSCGETN MIGGDEDSDN EPPVPPPTPD4380
 4381 VHENELQPYA MAPCASDPCE NGGSCSEQED VAVCSCPFGF SGKHCQEHLQ LGFNASFRGD4440
 4441 GYVELNRSHF QPALEQSYTS MGIVFTTNKP NGLLFWWGQE AGEEYTGQDF IAAAVVDGYV4500
 4501 EYSMRLDGEE AVIRNSDIRV DNGERHIVIA KRDENTAILE VDRMLHSGET RPTSKKSMKL4560
 4561 PGNVFVGGAP DLEVFTGFRY KHNLNGCIVV VEGETVGQIN LSSAAVNGVN ANVCPANDDP4620
 4621 LGGTEPPVV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: trol-PF

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: