Protein Overview: NHP6B

General Information:
Name(s) found:	NHP6B / YBR089C-A [SGD]
Description(s) found: SHOW ONLY BEST	gi\|45271022\|gb\|AAS56892.1\| YBR089C-A [Saccharomyces cerevisiae] [NCBI NR] gi\|4036\|emb\|CAA33378.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] High-mobility group (HMG) protein that binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; homologous to mammalian HMGB1 and HMGB2 [SGD] unnamed protein product [Saccharomyces cerevisiae]gi\|45271022\|gb\|AAS56892.1\| YBR089C-A [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YBR089C-A [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Non-histone chromosomal protein 6B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NHP6B PE=1 SV=3 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] NHP6B SGDID:S000002157, Chr II from 426489-426190, Genome Release 64-1-1, reverse complement, Verified ORF, "High-mobility group (HMG) protein that binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; homologous to mammalian HMGB1 and HMGB2" [yeast-030211-contam.fasta] NHP6B SGDID:S000002157, Chr II from 426489-426190, Genome Release 64-2-1, reverse complement, Verified ORF, "High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6B has a paralog, NHP6A, that arose from the whole genome duplication" [20141208_orf_trans.fasta] YBR089C-A SGDID:S000002157, Chr II from 426489-426190, Genome Release 64-1-1, reverse complement, Verified ORF, "High-mobility group (HMG) protein that binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; homologous to mammalian HMGB1 and HMGB2" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	99 amino acids
Gene Ontology:
Cellular Component:	nuclear chromatin [ISS]
Biological Process:	chromatin remodeling [IMP] chromatin organization [ISS] positive regulation of transcription from RNA polymerase II promoter [IMP][IPI] regulation of transcription from RNA polymerase III promoter [IDA][IGI][IMP] regulation of transcription from RNA polymerase II promoter [ISS]
Molecular Function:	chromatin binding [IDA][ISS]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MAATKEAKQP KEPKKRTTRR KKDPNAPKRG LSAYMFFANE NRDIVRSENP DVTFGQVGRI 60 61 LGERWKALTA EEKQPYESKA QADKKRYESE KELYNATRA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle