Protein Overview: MON1

General Information:
Name(s) found:	MON1 / YGL124C [SGD]
Description(s) found: SHOW ONLY BEST	Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate [SGD] [S288C.fasta] Vacuolar fusion protein MON1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MON1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] MON1 SGDID:S000003092, Chr VII from 276714-274780, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate" [yeast-030211-contam.fasta] MON1 SGDID:S000003092, Chr VII from 276714-274780, Genome Release 64-2-1, reverse complement, Verified ORF, "Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; role in localizing Ypt7p to the vacuolar membrane; required for autophagy, the CVT pathway and mitophagy; potential Cdc28 substrate" [20141208_orf_trans.fasta] YGL124C SGDID:S000003092, Chr VII from 276714-274780, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	644 amino acids
Gene Ontology:
Cellular Component:	fungal-type vacuole membrane [IDA] cytosol [IDA]
Biological Process:	autophagy [IMP] vesicle docking [IMP] protein targeting to vacuole [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLNESYLDA EIPKGQLKHS KSGNFEGIPI VATTSEPTTS VNLDETFFKK APIAMPICDD  60
   61 HSVSKSTSVN SLNTTSLASR RSPLQTKKLQ AKNNLLSADL AKSNDDTTRA LNSPKKDFGP 120
  121 YLDSENDIRS RLAESIYSME TSIRGSELQR RPYVSNEIPN VFKFSKFNSN CKLNESQTLC 180
  181 DKNFFIFTSA GKPIYCMHGK DEQIMSYTGL VNTVISYFQV NGPSELKTIS TLTSGKRLTF 240
  241 LDKSPILLMA QSERGESSNE LLNQLDFLYS YILSSLSERQ LLRLFSKREN FDLRNYLEST 300
  301 DFENLDEICS LICNRMFPDL LLNSLQCLPF NHSSRLKLQN VVLQQLEKRQ DIPRGTLLYG 360
  361 LIIAPQNKLC CVLRPRGHTL HTTDLHLLFC LISHQFQNLD ETQELWVPIC FPKFNSSGFL 420
  421 YCYIKFLPND THSNEKSALV LISAQKDAFF SLKSFSDELI IKLEEEKLLK KINTSKGFKL 480
  481 SDIPAPMVHH FIYKSKQNVQ YVMPHFEVNS NIALDSSQGL EYELKLKTYY QQLHGTVVRD 540
  541 NGNLLSRSML NFVRWSSKDN EDLAMDETQM DFSELDEYII GNSSFKQESV NMVGMAWVTP 600
  601 TFELYLIGNN GIVDKRVLFK SARKVANWCQ KHESRLFISD GAVF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.92

Protein Overview: MON1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: