Protein Overview: TSC10

General Information:
Name(s) found:	TSC10 / YBR265W [SGD]
Description(s) found: SHOW ONLY BEST	3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase/reductase protein family [SGD] [chemostatdb.fasta] 3-ketodihydrosphingosine reductase TSC10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TSC10 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] TSC10 SGDID:S000000469, Chr II from 738582-739544, Genome Release 64-1-1, Verified ORF, "3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase/reductase protein family" [yeast-030211-contam.fasta] TSC10 SGDID:S000000469, Chr II from 738582-739544, Genome Release 64-2-1, Verified ORF, "3-ketosphinganine reductase; catalyzes the second step in phytosphingosine synthesis; essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine; localized to lipid droplets; member of short chain dehydrogenase/reductase protein family" [20141208_orf_trans.fasta] YBR265W SGDID:S000000469, Chr II from 738582-739544, Genome Release 64-1-1, Verified ORF, "3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase/reductase protein family" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	320 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA] endoplasmic reticulum [IDA ] mitochondrial outer membrane [IDA]
Biological Process:	3-keto-sphinganine metabolic process [IDA] sphingolipid biosynthetic process [IDA][IMP][ISS]
Molecular Function:	oxidoreductase activity, acting on NADH or NADPH [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFTLEDQVV LITGGSQGLG KEFAKKYYNE AENTKIIIVS RSEARLLDTC NEIRIEAHLR  60
   61 RETTDEGQVQ HKLAAPLDLE QRLFYYPCDL SCYESVECLF NALRDLDLLP TQTLCCAGGA 120
  121 VPKLFRGLSG HELNLGMDIN YKTTLNVAHQ IALAEQTKEH HLIIFSSATA LYPFVGYSQY 180
  181 APAKAAIKSL VAILRQELTN FRISCVYPGN FESEGFTVEQ LTKPEITKLI EGPSDAIPCK 240
  241 QACDIIAKSL ARGDDDVFTD FVGWMIMGMD LGLTAKKSRF VPLQWIFGVL SNILVVPFYM 300
  301 VGCSWYIRKW FRENDGKKAN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TSC10

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: