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Protein Overview: PRS4

General Information:
Name(s) found: PRS4 / YBL068W [SGD]
Description(s) found:
Found 6 descriptions.
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  • 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 326 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: 'de novo' pyrimidine base biosynthetic process [TASLink to PubMed article]
    tryptophan biosynthetic process [TASLink to PubMed article]
    'de novo' IMP biosynthetic process [TASLink to PubMed article]
    ribosome biogenesis [RCALink to PubMed article]
    histidine biosynthetic process [TASLink to PubMed article]
    purine ribonucleoside salvage [TASLink to PubMed article]
    Molecular Function: ribose phosphate diphosphokinase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSESREDMA INSIKLLAGN SHPDLAEQIS KKLGIPLSKV GVYQYSNKET SVTIGESLRD  60
   61 EDVYIIQTGI GEQEINDFLM ELLILIHACK IASARKITTV IPNFPYARQD KKDKSRAPIT 120
  121 AKLVANLLQT AGADHVITMD LHASQIQGFF HIPVDNLYAE PSVLNYIRTK TDFDNAILVS 180
  181 PDAGGAKRVA ALADKLDLNF ALIHKERQKA NEVSKMVLVG DVTNKSCLLV DDMADTCGTL 240
  241 VKACDTLMEH GAKEVIAIVT HGIFSGSARE KLRNSRLSRI VCTNTVPVDL DLPIADQIDI 300
  301 SPTFAEAIRR LHNGESVSYL FTHAPV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle