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View Structure Prediction Details

Protein: gi|45445606, gi|...
Organism: Drosophila melanogaster
Length: 992 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|45445606, gi|....

Description E-value Query
Range
Subject
Range
gi|509068 - gi|509068|emb|CAA84345.1| voltage-dependent L-type Ca channel alpha 1 subunit [Homo sapiens]
470.0 [0..13] [917..1166]

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Predicted Domain #1
Region A:
Residues: [1-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPDNDIYAF YDIRGYKGKC RPGRPNSERI LQPRMSLLGK PLNYNRGTRR DVRYRRLQSR  60
   61 LYNFLERPRG LHAIFYHVMV FLMVFTCLAL SVFSTIKEYE EDAVYILFRM EILVVIWFTM 120
  121 EFGARLWSSG CRSRYQGCLG RLKFVKRPFC IIDIVTILAS IVVLGMGTSG QVFATSALRG 180
  181 LRFFQILRMV RMDRRGGTWK LLGSVVYAHR QELITTMYIG FLGLIFASFL VYMWEKDVND 240
  241 KFSNFAQALW WGITLCTVGY GDMVPITWQG KLIASCCALL GISFFALPAG ILGSGFALKV 300
  301 QQQQRQKHMI RRRQPAATLI QAVWRCYAAD EHSVSVATWN IHRVALPSPP ASRASSSFKH 360
  361 NTSFVARLPT IRRHKSQTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.69897
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [380-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTPGGGDGGG VSKPPGSSRA STRYTRTIRD INASVENLEV VQNGKSMNPS FSEDSVAETT  60
   61 CLKNIKNSDA SQPATLANCK LSSSAGSLAQ FPDRNRDRDQ DRRGHGEGEG DQAEEQAK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [498-688]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGGSRRNLTI PVVLYGFLHG NFLGSTLSLR NPRVAPANDR DLEAGRDEDE VHKDTCQRSN  60
   61 TLPLPVKPDS PSGSPGSGRT GRFFAAASHF LETGFSSPNP IIDVANEEDE PRCTQLTNRH 120
  121 KTAIRFIRKL KYFVARRKFK EALKPYDVKD VMEQYAAGHV DLLGRVKMLH LRLDQILGKQ 180
  181 GSKAKDVYAS K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [689-755]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISLASRVVKV ERQVADIEEK LDILIKAYME DRDRFLALPL PAKPKIHSIS PSHKPLHHAH  60
   61 NLAMIDV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [756-992]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WKRTAALSVH PEQVTTTPLL NPSAPDSSEL RSLTATQTPT TTTDAIATQT PMPPHVQHTA  60
   61 TNTKSSVLNS YQLGSEKQQH NDVFMTELEN RTKKRVTLSL HRSTSEPYSK QEQRITIPDE 120
  121 GADSLDSSAK PTPPDSSIIL IDEYEDFEEE DLNCEGEMDH FPTWEIDSDI GVEVDVDADA 180
  181 DGDCDESTED TALLQCATRT AIVITPISPV SSAHNLQQLN DQTTTLNKSN LLPPDSG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle