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View Structure Prediction Details

Protein: gi|45445605, gi|...
Organism: Drosophila melanogaster
Length: 807 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|45445605, gi|....

Description E-value Query
Range
Subject
Range
KCNQ-PE - The gene KCNQ potassium channel is referred to in FlyBase by the symbol Dmel\KCNQ (CG33135, FBgn0033...
500.0 [0..1] [807..1]

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Predicted Domain #1
Region A:
Residues: [1-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPDNDIYAF YDIRGYKGKC RPGRPNSERI LQPRMSLLGK PLNYNRGTRR DVRYRRLQSR  60
   61 LYNFLERPRG LHAIFYHVMV FLMVFTCLAL SVFSTIKEYE EDAVYILFRM EILVVIWFTM 120
  121 EFGARLWSSG CRSRYQGCLG RLKFVKRPFC IIDIVTILAS IVVLGMGTSG QVFATSALRG 180
  181 LRFFQILRMV RMDRRGGTWK LLGSVVYAHR QELITTMYIG FLGLIFASFL VYMWEKDVND 240
  241 KFSNFAQALW WGITLCTVGY GDMVPITWQG KLIASCCALL GISFFALPAG ILGSGFALKV 300
  301 QQQQRQKHMI RRRQPAATLI QAVWRCY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.39794
Match: 2a79B
Description: Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [328-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AADEHSVSVA TWNIHRVALP SPPASRASSS FKHNTSFVAR LPTIRRHKSQ TIQTPGGGDG  60
   61 GGVSKPPGSS RASTRYTRTI RDINASVENL DEEDEPRCTQ LTNRHKTAIR FIRKLKYFVA 120
  121 RRKFKEALKP YDVKDVMEQY AAGHVDLLGR VKMLHLRLDQ ILGKQGSKA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.154902
Match: 2qksA
Description: No description for 2qksA was found.

Predicted Domain #3
Region A:
Residues: [497-590]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDVYASKISL ASRVVKVERQ VADIEEKLDI LIKAYMEDRD RFLALPLPAK PKIHSISPSH  60
   61 KPLHHAHNLA MIDVWKRTAA LSVHPEQVTT TPLL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [591-807]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPSAPDSSEL RSLTATQTPT TTTDAIATQT PMPPHVQHTA TNTKSSVLNS YQLGSEKQQH  60
   61 NDVFMTELEN RTKKRVTLSL HRSTSEPYSK QEQRITIPDE GADSLDSSAK PTPPDSSIIL 120
  121 IDEYEDFEEE DLNCEGEMDH FPTWEIDSDI GVEVDVDADA DGDCDESTED TALLQCATRT 180
  181 AIVITPISPV SSAHNLQQLN DQTTTLNKSN LLPPDSG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle