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View Structure Prediction Details

Protein: CG1646-PB
Organism: Drosophila melanogaster
Length: 1066 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG1646-PB.

Description E-value Query
Range
Subject
Range
gi|220947196 - gi|220947196|gb|ACL86141.1| CG1646-PA [synthetic construct]
CG1646-PC, CG164... - This gene is referred to in FlyBase by the symbol Dmel\CG1646 (CG1646, FBgn0039600). It is a protein...
420.0 [0..58] [1066..1]

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Predicted Domain #1
Region A:
Residues: [1-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASEGENVVM ESPGRRTRSG RKAASPAASL PTRSTRRTSK RNVQLSDHEE EAEEQVVMVQ  60
   61 EEEEPFRGTN TAEAPALEPQ FEETQHQIED DVEMLPAEAA GVDEKSSSFP FGTVAELHSE 120
  121 TSDDIKETRG QAGVDTLLAS LAGDNANSLP SVGGNDESDN VKKADFEYNV DSLQPQMEKM 180
  181 NSSEDSSSQH AIAEDLADAD TSNATIVNTE IVSEDEL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [218-355]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLPSKPEIND AEEVSDEELP APQRAELPED AEVISEDELP ASNNNNTATE PKAPLKRKAE  60
   61 NESVKSTEDK DASSHESSTK DKSSEQYNPG SPTSESNDAQ PSEKKLKVEE SEPKEKKKEK 120
  121 ERDKDKEKDK DKDNNKDK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [356-466]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKERKKLPDL DKYWRAVKED STDFTGWTYL LQYVDNESDA EAAREAYDTF LSHYPYCYGY  60
   61 WRKYADYEKR KGIKANCYKV FERGLEAIPL SVDLWIHYLM HVKSNHGDDE T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.69897
Match: 2ooeA
Description: No description for 2ooeA was found.

Predicted Domain #4
Region A:
Residues: [467-986]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVRSQYERAV KACGLEFRSD KLWDAYIRWE NESKRYHRVV QIYDRLLAIP TQGYNGHFDN  60
   61 FQDLINQHDV TITLANEEVI RLRKDFHERQ QSKSSKSSSK HRRDSSSSSK DKDSKERERE 120
  121 KDKDKDKDKD KEKRETVGGG VGKSPKDTSE TQVDESDSTT DLTTESESSH AASKPAMQID 180
  181 FSDLSTLNDE EVVSIRDRAI SARRKVHKLT VSAVTARWSF EEGIKRPYFH VKPLERAQLK 240
  241 NWKDYLDFEI EKGDRERVLV LFERCLIACA LYDEFWLKML RYLESLEDQS GVVDLVRDVY 300
  301 RRACRIHHPD KPSLHLMWAA FEECQMNFDD AAEILQRIDQ RCPNLLQLSY RRINVERRRG 360
  361 ALDKCRELYK HYIESTKNKG IAGSLAIKYA RFLNKICHDL DAGLAALQQA LERDPANTRV 420
  421 ALQMIDLCLQ RPKVDEQEVV EIMDKFMARA DIEPDQKVLF AQRKVEFLED FGSTARGLQD 480
  481 AQRALQQALT KAKEAQKKSD GSPSRKNSSS SKEGPVPTGS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.522879
Match: 2gw1A
Description: No description for 2gw1A was found.

Predicted Domain #5
Region A:
Residues: [987-1066]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAAAYNNGGS AAAVAGYNYG AANPYYGQQN TAAAYPSQTP QQASYDSYYN QWGYGSGGAS  60
   61 ANSGGSGYNY GQWSGYGNYY 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.981
Match: 1rh1A
Description: crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle