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View Structure Prediction Details

Protein: FBpp0301185
Organism: Drosophila melanogaster
Length: 777 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0301185.

Description E-value Query
Range
Subject
Range
AMD3_MOUSE, AMPD... - AMP deaminase 3 OS=Mus musculus GN=Ampd3 PE=2 SV=1, (O08739) AMP deaminase 3 (EC 3.5.4.6) (AMP deami...
777.0 [0..1] [775..8]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFNRMDTAH RLRVDVRLYG GSMGNQLNDK GTASSTPTIS SDDLSDLADS PVDEKAEADV  60
   61 EVTNEISAPY EVPQFPIEQI EKKLQIQRHL NE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [93-777]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQATGPRPVA TAAVLATNRE SSSSTEGRES AVTMERNDAD INFQRVSISG EDTSGVPLED  60
   61 LERASTLLIE ALRLRSHYMA MSDQSFPSTT ARFLKTVKLK DRINNLPVKE VSESADVHLR 120
  121 HSPMKITNPW NVEFPNDEDF KIKPLNGVFH IYENDDESSE IKYEYPDMSQ FVNDMQVMCN 180
  181 MIADGPLKSF CYRRLCYLSS KYQMHVLLNE LRELAAQKAV PHRDFYNTRK VDTHIHAASC 240
  241 MNQKHLLRFI KKTLKNNANE VVTVTNGQQM TLAQVFQSMN LTTYDLTVDM LDVHADRNTF 300
  301 HRFDKFNSKY NPIGESRLRE VFLKTDNYLN GKYFAQIIKE VAFDLEESKY QNAELRLSIY 360
  361 GKSPDEWYKL AKWAIDNDVY SSNIRWLIQI PRLFDIFKSN KMMKSFQEIL NNIFLPLFEA 420
  421 TARPSKHPEL HRFLQYVIGF DSVDDESKPE NPLFDNDVPR PEEWTYEENP PYAYYIYYMY 480
  481 ANMTVLNKFR QSRNMNTFVL RPHCGEAGPV QHLVCGFLMA ENISHGLLLR KVPVLQYLYY 540
  541 LTQIGIAMSP LSNNSLFLNY HRNPLPEYLA RGLIISLSTD DPLQFHFTKE PLMEEYSIAA 600
  601 QVWKLSSCDM CELARNSVMM SGFPHAIKQQ WLGPIYYEDG IMGNDITRTN VPEIRVAYRY 660
  661 ETLLDELSNI FKVNQTCSIA DMNAT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 174.0
Match: 2a3lA
Description: X-Ray Structure of Adenosine 5'-Monophosphate Deaminase from Arabidopsis Thaliana in Complex with Coformycin 5'-Phosphate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.935564737557247 bayes_pls_golite062009
hydrolase activity 0.928922745938392 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle