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View Structure Prediction Details

Protein: Trf4-1-PC, Trf4-...
Organism: Drosophila melanogaster
Length: 1001 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Trf4-1-PC, Trf4-....

Description E-value Query
Range
Subject
Range
gi|22831959, gi|... - gi|45554563|ref|NP_996383.1| CG11265-PB, isoform B [Drosophila melanogaster], gi|45554556|ref|NP_996...
550.0 [0..1] [1001..1]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPFVGWFQK EQEGPSLCTW LKIWETNAQE MGALLNQQLQ QATTINGSTS SSSSSSNSGN  60
   61 NNNNNNNNII NNTITNTTNN TGNNSSAKPY LSRPYSSLNR VLNFRADSLE ILQQQQQQQQ 120
  121 LNGTTQRNST NINTTSGGST SSSADSTTNR DN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [153-256]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSPANSSSTN GPGAGTGTST GAGGTGTNSP ATTASSTAAT TTGPATSMSD TSNNPPQSTT  60
   61 TPASRTNSIY YNPSRKKRPE NKAGGAHYYM NNHMEMIAKY KGEP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.522879
Match: 2b4vA
Description: Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [257-721]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WRKPDYPYGE GVIGLHEEIE HFYQYVLPTP CEHAIRNEVV KRIEAVVHSI WPQAVVEIFG  60
   61 SFRTGLFLPT SDIDLVVLGL WEKLPLRTLE FELVSRGIAE ACTVRVLDKA SVPIIKLTDR 120
  121 ETQVKVDISF NMQSGVQSAE LIKKFKRDYP VLEKLVLVLK QFLLLRDLNE VFTGGISSYS 180
  181 LILMCISFLQ MHPRGIYHDT ANLGVLLLEF FELYGRRFNY MKIGISIKNG GRYMPKDELQ 240
  241 RDMVDGHRPS LLCIEDPLTP GNDIGRSSYG VFQVQQAFKC AYRVLALAVS PLNLLGIDPR 300
  301 VNSILGRIIH ITDDVIDYRE WIRENFEHLV VVDRISPLPT AAPTAYATAN GAPKYVIMPS 360
  361 GAVVQQLYHH PVQVPTAHGH SHAHSHSHGH AHPGAHLCQP YVTGTTVSAV TTTTTMAVVT 420
  421 VGVSAGGVQQ QQQQQNATAH THSQQQTQNQ SQSRHRRGST SSGDD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.69897
Match: 1q78A
Description: Crystal structure of poly(A) polymerase in complex with 3'-dATP and magnesium chloride
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.222270543382941 bayes_pls_golite062009
transferase activity 0.00393984128503999 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [722-825]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEDSKDGDVV ETTSSAQEVV DIALSTPNGL ANMSMPMPVH AVGMPASNSW SGNGNGNGNS  60
   61 SSSTGSSPEI AHIAAQEMDP ELEDQQQQQQ HQETSGGNGF IRPG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [826-1001]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVGTGSNRGG GDGSGGRNYN QRNNHNSSGY YHQQYYVPPP MQQQLSKSNS SSNYHQQHHH  60
   61 SHSHGNHSHR QQHHHQQQHH HQQRPQHLRV GGGNRYQKSL GGSPIISAGN ASNSSSNCSN 120
  121 SSSSSGSNNS RLPPLRGTLV NSSSAISIIS ISSESSIASS SSSSSRSGQD QQRDER

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle