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View Structure Prediction Details

Protein: mip130-PA
Organism: Drosophila melanogaster
Length: 986 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mip130-PA.

Description E-value Query
Range
Subject
Range
gi|27369419 - gi|27369419|gb|AAN87841.1| TGS2 [Homo sapiens]
331.0 [0..134] [484..107]

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Predicted Domain #1
Region A:
Residues: [1-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTGRPVRMS VAVNQKGWGK KAGASVSDSA IRTQSALSEG GGAIDVRPME HDEEINREDL  60
   61 NLDEDDEMEE EEEEEHADEE DDDEEPDSNE NSAPEEQVEP PAFSLATLGL QRVGSAPPPK 120
  121 PKVQKAPIPT LNARGMPARI RKRNRLFYDE NIINDDKPLR MSLAPKKTPG RPPQSAGGGS 180
  181 SQKIPLTPSK VLKKRKGVVS RYMRSSEQGT NSVSASNQPQ LLGKHKKATP SKSQSVGSKL 240
  241 GSGGPKTGRG AHFIGKGTAA AVAAVAAAEE EANQAEAAAL ANKRLGQSIG LRLRNLLKLP 300
  301 KAHKWAIAEW FYSYV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [316-468]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKPLFECRDE FMNHVNELAP RLGTRSLIRH EWVNIRRRMG RPRRCSAKFF SEERKELDRK  60
   61 RQVIRTLQSR KPGEFKDSVS MLSDMPEKIP MTLPLGTKVT ARLRSPQDGI FAGTVAAYDS 120
  121 LNAMYRVTFE RIGLGTHAIP DYEIVSENFH EML

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 72.769551
Match: PF06584.4
Description: No description for PF06584.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [469-568]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLHSFTKDFR PNLMSIYQTN NLGFTTNLGF TANLTNNYLQ KKEKIDGGAG AAAGAGSLYF  60
   61 KPQKHLATNN AAARNALSMK LNKSDPLLGQ DSVGVSPIRQ 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [569-906]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLTRNRGYST SLLEHLVRLE KYIAVKADRI QRLNKMNGTA ELAMGDMISH DENGDRHRRQ  60
   61 IAVNFQRQYA FNIVTIERIN AELMFELTKV QELSSSLTRN PNVQAMISPT YLREECRAKA 120
  121 SQTVDDINKG MVKNTRMIKL LKDLTTLLIV TQNLGGDCEV SEVNEVLEGC LEEVRSNLIC 180
  181 SENREVFQMS VQGRLEYIAM DISRRLEEKS LSRVADGDDD IKSLKSEDET DEDHVQDHKH 240
  241 GADEEPAADT SKTKAKGSPK QVEGKENSEV DKMDHSSHPM DTDTEKEEKL ESGGSENAGY 300
  301 ASQQRQDEDQ DTEEQHLDLE EQHLDPEEHH LDLEEQHL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.30103
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [907-986]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPEEQHLDLE EHHLELEEQH LDPEEQSLNP AVTEDTQITI ESMKESDEEF QSAAETEEDD  60
   61 MVGLIMEEEE EEEFVYDKDL 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle