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View Structure Prediction Details

Protein: CENPI
Organism: Homo sapiens
Length: 756 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CENPI.

Description E-value Query
Range
Subject
Range
gi|1628401, gi|2... - sp|Q92674|FSP1_HUMAN Leucine-rich primary response protein 1 (Follicle-stimulating hormone primary r...
1158.0 [0..1] [756..1]
CENPI_MOUSE - Centromere protein I OS=Mus musculus GN=Cenpi PE=2 SV=1
1095.0 [0..1] [748..1]
gi|109131540, gi... - gi|109131542|ref|XP_001092023.1| PREDICTED: similar to follicle-stimulating hormone primary response...
1091.0 [0..1] [756..1]
gi|74008206 - gi|74008206|ref|XP_549138.2| PREDICTED: similar to follicle-stimulating hormone primary response pro...
1066.0 [0..1] [745..114]
CENPI_RAT - Centromere protein I OS=Rattus norvegicus GN=Cenpi PE=2 SV=1
1059.0 [0..1] [748..1]
gi|114689433 - gi|114689433|ref|XP_521177.2| PREDICTED: follicle-stimulating hormone primary response protein 1 [Pa...
1038.0 [0..1] [700..1]
CENPI_CHICK - Centromere protein I OS=Gallus gallus GN=CENPI PE=1 SV=1
946.0 [0..5] [743..2]

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Predicted Domain #1
Region A:
Residues: [1-59]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPQKRVKNV QAQNRTSQGS SSFQTTLSAW KVKQDPSNSK NISKHGQNNP VGDYEHADD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.597 N/A N/A a.64.1 Saposin
View Download 0.471 N/A N/A a.64.1 Saposin
View Download 0.441 N/A N/A a.64.1 Saposin
View Download 0.441 N/A N/A a.64.1 Saposin
View Download 0.405 N/A N/A a.3.1 Cytochrome c
View Download 0.392 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.383 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.383 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.380 N/A N/A a.4.1 Homeodomain-like
View Download 0.366 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.271 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.263 N/A N/A d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.247 N/A N/A a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #2
Region A:
Residues: [60-231]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QAEEDALQMA VGYFEKGPIK ASQNKDKTLE KHLKTVENVA WKNGLASEEI DILLNIALSG  60
   61 KFGNAVNTRI LKCMIPATVI SEDSVVKAVS WLCVGKCSGS TKVLFYRWLV AMFDFIDRKE 120
  121 QINLLYGFFF ASLQDDALCP YVCHLLYLLT KKENVKPFRV RKLLDLQAKM GM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [232-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPHLQALLSL YKFFAPALIS VSLPVRKKIY FKNSENLWKT ALLAVKQRNR GPSPEPLKLM  60
   61 LGPANVRPLK RKWNSLSVIP VLNSSSYTKE CG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [324-517]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKEMSLSDCL NRSGSFPLEQ LQSFPQLLQN IHCLELPSQM GSVLNNSLLL HYINCVRDEP  60
   61 VLLRFYYWLS QTLQEECIWY KVNNYEHGKE FTNFLDTIIR AECFLQEGFY SCEAFLYKSL 120
  121 PLWDGLCCRS QFLQLVSWIP FSSFSEVKPL LFDHLAQLFF TSTIYFKCSV LQSLKELLQN 180
  181 WLLWLSMDIH MKPV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [518-612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNSPLETTLG GSMNSVSKLI HYVGWLSTTA MRLESNNTFL LHFILDFYEK VCDIYINYNL  60
   61 PLVVLFPPGI FYSALLSLDT SILNQLCFIM HRYRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.780 a.4.1 Homeodomain-like
View Download 0.703 a.24.17 Group V grass pollen allergen
View Download 0.703 a.24.17 Group V grass pollen allergen
View Download 0.696 a.59.1 PAH2 domain
View Download 0.691 a.59.1 PAH2 domain
View Download 0.623 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.623 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.620 a.7.16 Description not found.
View Download 0.614 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.572 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.475 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.434 a.16.1 S15/NS1 RNA-binding domain
View Download 0.418 a.83.1 Guanido kinase N-terminal domain
View Download 0.389 a.7.8 GAT domain

Predicted Domain #6
Region A:
Residues: [613-658]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLTAAKKNEL VQKTKSEFNF SSKTYQEFNH YLTSMVGCLW TSKPFG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.567 N/A N/A a.140.2 SAP domain
View Download 0.561 N/A N/A a.140.3 Rho termination factor, N-terminal domain
View Download 0.531 N/A N/A a.140.3 Rho termination factor, N-terminal domain
View Download 0.519 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.519 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.508 N/A N/A a.140.2 SAP domain
View Download 0.494 N/A N/A a.8.5 Description not found.
View Download 0.482 N/A N/A a.140.1 LEM domain
View Download 0.457 N/A N/A a.144.2 Ribosomal protein L20
View Download 0.425 N/A N/A a.144.2 Ribosomal protein L20
View Download 0.423 N/A N/A a.144.2 Ribosomal protein L20
View Download 0.271 N/A N/A a.8.5 Description not found.
View Download 0.250 N/A N/A a.8.5 Description not found.
View Download 0.248 N/A N/A a.8.5 Description not found.

Predicted Domain #7
Region A:
Residues: [659-756]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KGIYIDPEIL EKTGVAEYKN SLNVVHHPSF LSYAVSFLLQ ESPEERTVNV SSIRGKKWSW  60
   61 YLDYLFSQGL QGLKLFIRSS VHHSSIPRAE GINCNNQY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.779 a.60.1 SAM/Pointed domain
View Download 0.764 a.280.1 Description not found.
View Download 0.757 a.77.1 DEATH domain
View Download 0.625 a.60.8 HRDC-like
View Download 0.617 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.617 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.603 d.57.1 DNA damage-inducible protein DinI
View Download 0.585 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.567 a.77.1 DEATH domain
View Download 0.555 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.511 c.47.1 Thioredoxin-like
View Download 0.409 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.338 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle