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View Structure Prediction Details

Protein: gi|1399805, gi|4...
Organism: Homo sapiens
Length: 1005 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1399805, gi|4....

Description E-value Query
Range
Subject
Range
gi|112799849, gi... - gi|211828528|gb|AAH58918.2| TP53BP2 protein [Homo sapiens], gi|194377458|dbj|BAG57677.1| unnamed pro...
gi|168277530 - gi|168277530|dbj|BAG10743.1| tumor protein p53 binding protein, 2 [synthetic construct]
0.0 [1..1005] [130..1134]
gi|109018201 - gi|109018201|ref|XP_001093747.1| PREDICTED: tumor protein p53 binding protein, 2 [Macaca mulatta]
0.0 [1..1005] [408..1412]
gi|109498318 - gi|109498318|ref|XP_223012.4| PREDICTED: similar to Apoptosis-stimulating of p53 protein 2 (Tumor su...
0.0 [1..1000] [146..1140]
gi|112799851 - gi|112799851|ref|NP_775554.2| tumor protein p53 binding protein, 2 [Mus musculus]
0.0 [1..1005] [130..1134]
gi|73961509 - gi|73961509|ref|XP_547518.2| PREDICTED: similar to Apoptosis stimulating of p53 protein 2 (Tumor sup...
0.0 [1..990] [251..1239]

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Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLTLAELQE MASRQQQQIE AQQQLLATKE QRLKFLKQQD QRQQQQVAEQ EKLKRLKEIA  60
   61 ENQEAKLKKV RALKGHVEQK RLSNGKLVEE IEQMNNLFQQ KQRELVLAVS KVEELTRQLE 120
  121 MLKNGRIDSH HDNQSAVAEL DRLYKELQLR NKLNQEQNAK LQQQRECLNK RNSEVAVMDK 180
  181 RVNELRDRLW KKKAALQQKE NLPVSSDGNL PQQAASAPSR VAAVGPYIQS STMPRMPSRP 240
  241 ELLVKPALPD GSLVIQASEG PMKIQTLPNM RSGAASQTKG SKIHPVG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [288-568]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDWSPSNADL FPSQGSASVP QSTGNALDQV DDGEVPLREK EKKVRPFSMF DAVDQSNAPP  60
   61 SFGTLRKNQS SEDILRDAQV ANKNVAKVPP PVPTKPKQIN LPYFGQTNQP PSDIKPDGSS 120
  121 QQLSTVVPSM GTKPKPAGQQ PRVLLSPSIP SVGQDQTLSP GSKQESPPAA AVRPFTPQPS 180
  181 KDTLLPPFRK PQTVAASSIY SMYTQQQAPG KNFQQAVQSA LTKTHTRGPH FSSVYGKPVI 240
  241 AAAQNQQQHP ENIYSNSQGK PGSPEPETEP VSSVQENHEN E

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [569-643]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RIPRPLSPTK LLPFLSNPYR NQSDADLEAL RKKLSNAPRP LKKRSSITEP EGPNGPNIQK  60
   61 LLYQRTTIAA METIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [644-900]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPSYPSKSAS VTASSESPVE IQNPYLHVEP EKEVVSLVPE SLSPEDVGNA STENSDMPAP  60
   61 SPGLDYEPEG VPDNSPNLQN NPEEPNPEAP HVLDVYLEEY PPYPPPPYPS GEPEGPGEDS 120
  121 VSMRPPEITG QVSLPPGKRT NLRKTGSERI AHGMRVKFNP LALLLDSSLE GEFDLVQRII 180
  181 YEVDDPSLPN DEGITALHNA VCAGHTEIVK FLVQFGVNVN AADSDGWTPL HCAASCNNVQ 240
  241 VCKFLVESGA AVFAMTY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.221849
Match: 2b0oE
Description: Crystal structure of UPLC1 GAP domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [901-1005]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDMQTAADKC EEMEEGYTQC SQFLYGVQEK MGIMNKGVIY ALWDYEPQND DELPMKEGDC  60
   61 MTIIHREDED EIEWWWARLN DKEGYVPRNL LGLYPRIKPR QRSLA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.522879
Match: 1ycsB
Description: 53BP2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle