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View Structure Prediction Details

Protein: NSUN2
Organism: Homo sapiens
Length: 767 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NSUN2.

Description E-value Query
Range
Subject
Range
gi|115501316 - gi|115501316|dbj|BAF34150.1| putative 5-methycytoisine methyltransferase [Homo sapiens]
0.0 [17..767] [17..767]
gi|114598922 - gi|114598922|ref|XP_517620.2| PREDICTED: NOL1/NOP2/Sun domain family 2 protein [Pan troglodytes]
0.0 [17..767] [17..767]
gi|74207211, gi|... - gi|74207211|dbj|BAE30795.1| unnamed protein product [Mus musculus], gi|74151867|dbj|BAE29720.1| unna...
0.0 [1..767] [1..757]
gi|109504531, gi... - gi|157822221|ref|NP_001101873.1| NOL1/NOP2/Sun domain family, member 2 [Rattus norvegicus], gi|14903...
0.0 [10..767] [35..782]
gi|74003041 - gi|74003041|ref|XP_535800.2| PREDICTED: similar to NOL1/NOP2/Sun domain family 2 protein isoform 1 [...
0.0 [19..766] [21..777]

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Predicted Domain #1
Region A:
Residues: [1-73]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRRSRGRRL QQQQRPEDAE DGAEGGGKRG EAGWEGGYPE IVKENKLFEH YYQELKIVPE  60
   61 GEWGQFMDAL REP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.154902
Match: 1sqfA
Description: The crystal structure of E. coli Fmu binary complex with S-Adenosylmethionine at 2.1 A resolution
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [74-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPATLRITGY KSHAKEILHC LKNKYFKELE DLEVDGQKVE VPQPLSWYPE ELAWHTNLSR  60
   61 KILRKSPHLE KFHQFLVSET ESGNISRQEA VSMIPPLLLN VRPHHKILDM CAAPGSKTTQ 120
  121 LIEMLHADMN VPFPEGFVIA NDVDNKRCYL LVHQAKRLSS PCIMVVNHDA SSIPRLQIDV 180
  181 DGRKEILFYD RILCDVPCSG DGTMRKNIDV WKKWTTLNSL QLHGLQLRIA TRGAEQLAEG 240
  241 GRMVYSTCSL NPIEDEAVIA SLLEKSEGAL ELADVSNELP GLKWMPGITQ WKVMTKDGQW 300
  301 FTDWDAVPHS RHTQIRPTMF PPKDPEKLQA MHLERCLRIL PHHQNTGGFF VAVLVKKSSM 360
  361 PWNKRQPKLQ GKSAETREST QLSPADLTEG KPTDPSKLES PSFTGTGDTE IAHATEDLEN 420
  421 NGSKKDGVCG PP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.09691
Match: 2frxA
Description: No description for 2frxA was found.

Predicted Domain #3
Region A:
Residues: [506-767]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSKKMKLFGF KEDPFVFIPE DDPLFPPIEK FYALDPSFPR MNLLTRTTEG KKRQLYMVSK  60
   61 ELRNVLLNNS EKMKVINTGI KVWCRNNSGE EFDCAFRLAQ EGIYTLYPFI NSRIITVSME 120
  121 DVKILLTQEN PFFRKLSSET YSQAKDLAKG SIVLKYEPDS ANPDALQCPI VLCGWRGKAS 180
  181 IRTFVPKNER LHYLRMMGLE VLGEKKKEGV ILTNESAAST GQPDNDVTEG QRAGEPNSPD 240
  241 AEEANSPDVT AGCDPAGVHP PR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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