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View Structure Prediction Details

Protein: RFX1
Organism: Homo sapiens
Length: 979 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFX1.

Description E-value Query
Range
Subject
Range
gi|26332070 - gi|26332070|dbj|BAC29765.1| unnamed protein product [Mus musculus]
714.0 [0..280] [979..3]
gi|114675711 - gi|114675711|ref|XP_524133.2| PREDICTED: regulatory factor X1 [Pan troglodytes]
684.0 [0..1] [979..1]
RFX1 - regulatory factor X, 1 (influences HLA class II expression)
684.0 [0..1] [979..1]
gi|73946688 - gi|73946688|ref|XP_533540.2| PREDICTED: similar to regulatory factor X3 isoform b isoform 1 [Canis f...
684.0 [0..240] [977..2]
gi|157786958, gi... - gi|62665033|ref|XP_222456.3| PREDICTED: similar to regulatory factor X, 1 (influences HLA class II e...
683.0 [0..94] [979..87]
gi|109111667 - gi|109111667|ref|XP_001086729.1| PREDICTED: similar to regulatory factor X3 isoform b isoform 6 [Mac...
681.0 [0..240] [977..2]
RFX3_MACFA - Transcription factor RFX3 OS=Macaca fascicularis GN=RFX3 PE=2 SV=1
680.0 [0..240] [977..2]

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Predicted Domain #1
Region A:
Residues: [1-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATQAYTELQ AAPPPSQPPQ APPQAQPQPP PPPPPAAPQP PQPPTAAATP QPQYVTELQS  60
   61 PQPQAQPPGG QKQYVTELPA VPAPSQPTGA PTPSPAPQQY IVVTVSEGAM RASETVSEAS 120
  121 PGSTASQTGV PTQVVQQVQG TQQRLLVQTS VQAKPGHVSP LQLTNIQVPQ QALPTQRLVV 180
  181 QSAAPGSKGG QVSLTVHGTQ QVHSPPEQSP VQANSSSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [219-419]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTAGAPTGTV PQQLQVHGVQ QSVPVTQERS VVQATPQAPK PGPVQPLTVQ GLQPVHVAQE  60
   61 VQQLQQVPVP HVYSSQVQYV EGGDASYTAS AIRSSTYSYP ETPLYTQTAS TSYYEAAGTA 120
  121 TQVSTPATSQ AVASSGSMPM YVSGSQVVAS STSTGAGASN SSGGGGSGGG GGGGGGGGGG 180
  181 GSGSTGGGGS GAGTYVIQGG Y

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 108.677781
Match: PF04589.3
Description: No description for PF04589.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [420-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGSASQSYS HTTRASPATV QWLLDNYETA EGVSLPRSTL YCHYLLHCQE QKLEPVNAAS  60
   61 FGKLIRSVFM GLRTRRLGTR GNSKYHYYGL RIKASSPLLR LMEDQQHMAM RGQPFSQKQR 120
  121 LKPIQKMEGM TNGVAVGQQP STGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1dp7P
Description: Class II MHC transcription factor RFX1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [564-671]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDISAQVQQY QQFLDASRSL PDFTELDLQG KVLPEGVGPG DIKAFQVLYR EHCEAIVDVM  60
   61 VNLQFTLVET LWKTFWRYNL SQPSEAPPLA VHDEAEKRLP KAILVLLS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [672-863]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFEPVLQWTK HCDNVLYQGL VEILIPDVLR PIPSALTQAI RNFAKSLESW LTHAMVNIPE  60
   61 EMLRVKVAAA GAFAQTLRRY TSLNHLAQAA RAVLQNTAQI NQMLSDLNRV DFANVQEQAS 120
  121 WVCRCEDRVV QRLEQDFKVT LQQQNSLEQW AAWLDGVVSQ VLKPYQGSAG FPKAAKLFLL 180
  181 KWSFYSSMVI RD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [864-979]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTLRSAASFG SFHLIRLLYD EYMYYLIEHR VAQAKGETPI AVMGEFANLA TSLNPLDPDK  60
   61 DEEEEEEEES EDELPQDISL AAGGESPALG PETLEPPAKL ARTDARGLFV QALPSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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