YRC Public Data Repository - Protein Structure Prediction

Protein:	YPHB_ECOLI
Organism:	Escherichia coli
Length:	290 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPHB_ECOLI.

Description	E-value	Query Range	Subject Range
GALM_BOVIN - Aldose 1-epimerase OS=Bos taurus GN=GALM PE=2 SV=1	264.0	[0..1]	[288..19]
GALM_RAT - Aldose 1-epimerase OS=Rattus norvegicus GN=Galm PE=1 SV=1	262.0	[0..1]	[288..19]
gi\|73980750 - gi\|73980750\|ref\|XP_540154.2\| PREDICTED: similar to galactose mutarotase (aldose 1-epimerase) [Canis ...	260.0	[0..1]	[288..19]
GALM_PIG - Aldose 1-epimerase OS=Sus scrofa GN=GALM PE=2 SV=1	259.0	[0..1]	[288..19]
gi\|88805087, gi\|... - gi\|88805087\|ref\|ZP_01120607.1\| aldose 1-epimerase [Robiginitalea biformata HTCC2501], gi\|88785966\|gb...	258.0	[0..1]	[289..84]
GALM - galactose mutarotase (aldose 1-epimerase)	258.0	[0..1]	[288..19]
gi\|220677983, gi... - gi\|68370696\|ref\|XP_683202.1\| PREDICTED: similar to galactose mutarotase (aldose 1-epimerase) [Danio ...	257.0	[0..1]	[288..16]
gi\|113197877, gi... - gi\|148540076\|ref\|NP_001017024.2\| galactose mutarotase [Xenopus (Silurana) tropicalis], gi\|113197877\|...	256.0	[0..1]	[288..19]

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Predicted Domain #1

Region A:
Residues: [1-290]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIYTLSHGS LKLDVSDQGG VIEGFWRDTT PLLRPGKKSG VATDASCFPL VPFANRVSGN  60
   61 RFVWQGREYQ LQPNVEWDAH YLHGDGWLGE WQCVSHSDDS LCLVYEHRSG VYHYRVSQAF 120
  121 HLTADTLTVT LSVTNQGAET LPFGTGWHPY FPLSPQTRIQ AQASGYWLER EQWLAGEFCE 180
  181 QLPQELDFNQ PAPLPRQWVN NGFAGWNGQA RIEQPQEGYA IIMETTPPAP CYFIFVSDPA 240
  241 FDKGYAFDFF CLEPMSHAPD DHHRPEGGDL IALAPGESTT SEMSLRVEWL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.522879
Match:	1snzA
Description:	Crystal structure of apo human galactose mutarotase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
racemase and epimerase activity, acting on carbohydrates and derivatives	1.21567860634685	bayes_pls_golite062009
racemase and epimerase activity	1.19295069153058	bayes_pls_golite062009
catalytic activity	1.14137378674629	bayes_pls_golite062009
aldose 1-epimerase activity	0.631037634995041	bayes_pls_golite062009
isomerase activity	0.62004466537384	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: