YRC Public Data Repository - Protein Structure Prediction

Protein:	YJHG_ECOLI
Organism:	Escherichia coli
Length:	655 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJHG_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110334964, gi... - gi\|110595666\|ref\|ZP_01383994.1\| dihydroxy-acid dehydratase [Acidovorax sp. JS42], gi\|110334964\|gb\|EA...	770.0	[0..3]	[645..54]
ILVD_VIBPA - Dihydroxy-acid dehydratase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=ilvD P... ILVD_VIBPA - Dihydroxy-acid dehydratase OS=Vibrio parahaemolyticus GN=ilvD PE=3 SV=1	765.0	[0..28]	[645..2]
gi\|254229982, gi... - gi\|254229982\|ref\|ZP_04923383.1\| dihydroxy-acid dehydratase [Vibrio sp. Ex25], gi\|194538929\|ref\|YP_00...	762.0	[0..28]	[645..2]
gi\|91226246, gi\|... - gi\|91226246\|ref\|ZP_01261086.1\| dihydroxy-acid dehydratase [Vibrio alginolyticus 12G01], gi\|91189257\|...	761.0	[0..28]	[645..2]
gi\|67093561, gi\|... - gi\|67658934\|ref\|ZP_00456302.1\| Dihydroxy-acid dehydratase [Burkholderia cenocepacia AU 1054], gi\|670... gi\|116692231, gi... - gi\|67663692\|ref\|ZP_00460972.1\| Dihydroxy-acid dehydratase [Burkholderia cenocepacia HI2424], gi\|6710...	761.0	[0..28]	[646..2]
gi\|192926214, gi... - gi\|75255778\|ref\|ZP_00727532.1\| COG0129: Dihydroxyacid dehydratase/phosphogluconate dehydratase [Esch... gi\|193071056, gi... - gi\|75234068\|ref\|ZP_00718481.1\| COG0129: Dihydroxyacid dehydratase/phosphogluconate dehydratase [Esch... gi\|190903830, gi... - gi\|75230739\|ref\|ZP_00717202.1\| COG0129: Dihydroxyacid dehydratase/phosphogluconate dehydratase [Esch... ILVD_ECO8A - Dihydroxy-acid dehydratase OS=Escherichia coli O8 (strain IAI1) GN=ilvD PE=3 SV=1 gi\|75209006, gi\|... - gi\|75209006\|ref\|ZP_00709270.1\| COG0129: Dihydroxyacid dehydratase/phosphogluconate dehydratase [Esch... ILVD_ECO24 - Dihydroxy-acid dehydratase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=ilvD PE=3 SV=1 ILVD_SHIF8 - Dihydroxy-acid dehydratase OS=Shigella flexneri serotype 5b (strain 8401) GN=ilvD PE=3 SV=1 ILVD_ECOSE - Dihydroxy-acid dehydratase OS=Escherichia coli (strain SE11) GN=ilvD PE=3 SV=1	761.0	[0..28]	[645..2]
ILVD_SHIBS - Dihydroxy-acid dehydratase OS=Shigella boydii serotype 4 (strain Sb227) GN=ilvD PE=3 SV=1 ILVD_SHIB3 - Dihydroxy-acid dehydratase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=ilvD PE=3 ...	760.0	[0..28]	[645..2]
ILVD_SHISS - Dihydroxy-acid dehydratase OS=Shigella sonnei (strain Ss046) GN=ilvD PE=3 SV=1	760.0	[0..28]	[645..2]
gi\|191174378, gi... - gi\|75236527\|ref\|ZP_00720617.1\| COG0129: Dihydroxyacid dehydratase/phosphogluconate dehydratase [Esch... ILVD_ECO81 - Dihydroxy-acid dehydratase OS=Escherichia coli O81 (strain ED1a) GN=ilvD PE=3 SV=1 ILVD_ECOL5 - Dihydroxy-acid dehydratase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=ilvD PE=3 SV=1	760.0	[0..28]	[645..2]
ILVD_VIBVU - Dihydroxy-acid dehydratase OS=Vibrio vulnificus (strain CMCP6) GN=ilvD PE=3 SV=1 ILVD_VIBVU - Dihydroxy-acid dehydratase OS=Vibrio vulnificus GN=ilvD PE=3 SV=1	760.0	[0..28]	[645..2]

Back

Predicted Domain #1

Region A:
Residues: [1-655]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVRNIFADE SHDIYTVRTH ADGPDGELPL TAEMLINRPS GDLFGMTMNA GMGWSPDELD  60
   61 RDGILLLSTL GGLRGADGKP VALALHQGHY ELDIQMKAAA EVIKANHALP YAVYVSDPCD 120
  121 GRTQGTTGMF DSLPYRNDAS MVMRRLIRSL PDAKAVIGVA SCDKGLPATM MALAAQHNIA 180
  181 TVLVPGGATL PAKDGEDNGK VQTIGARFAN GELSLQDARR AGCKACASSG GGCQFLGTAG 240
  241 TSQVVAEGLG LAIPHSALAP SGEPVWREIA RASARAALNL SQKGITTREI LTDKAIENAM 300
  301 TVHAAFGGST NLLLHIPAIA HQAGCHIPTV DDWIRINKRV PRLVSVLPNG PVYHPTVNAF 360
  361 MAGGVPEVML HLRSLGLLHE DVMTVTGSTL KENLDWWEHS ERRQRFKQLL LDQEQINADE 420
  421 VIMSPQQAKA RGLTSTITFP VGNIAPEGSV IKSTAIDPSM IDEQGIYYHK GVAKVYLSEK 480
  481 SAIYDIKHDK IKAGDILVII GVGPSGTGME ETYQVTSALK HLSYGKHVSL ITDARFSGVS 540
  541 TGACIGHVGP EALAGGPIGK LRTGDLIEIK IDCRELHGEV NFLGTRSDEQ LPSQEEATAI 600
  601 LNARPSHQDL LPDPELPDDT RLWAMLQAVS GGTWTGCIYD VNKIGAALRD FMNKN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	178.0
Match:	2gp4A
Description:	No description for 2gp4A was found.

Predicted functions:

Term	Confidence	Notes
phosphogluconate dehydratase activity	6.35859617166212	bayes_pls_golite062009
3-isopropylmalate dehydratase activity	2.79463796576358	bayes_pls_golite062009
catalytic activity	1.99003321006923	bayes_pls_golite062009
dihydroxy-acid dehydratase activity	1.86041876362237	bayes_pls_golite062009
lyase activity	1.77649447753579	bayes_pls_golite062009
carbon-oxygen lyase activity	1.77249348870989	bayes_pls_golite062009
hydro-lyase activity	1.68972070574507	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: