YRC Public Data Repository - Protein Structure Prediction

Protein:	YIEF_ECOLI
Organism:	Escherichia coli
Length:	188 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIEF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|194431124, gi... - gi\|83571510\|ref\|ZP_00922950.1\| COG0431: Predicted flavoprotein [Shigella dysenteriae 1012], gi\|19443...	160.0	[0..1]	[188..1]
gi\|147918925, gi... - gi\|147918925\|ref\|YP_687349.1\| NADPH-dependent FMN reductase [uncultured methanogenic archaeon RC-I],...	159.0	[0..1]	[187..1]
gi\|187430410, gi... - gi\|75177717\|ref\|ZP_00697782.1\| COG0431: Predicted flavoprotein [Shigella boydii BS512], gi\|187733418...	157.0	[0..1]	[188..1]
gi\|227883935, gi... - gi\|227883935\|ref\|ZP_04001740.1\| possible NAD(P)H dehydrogenase (quinone) [Escherichia coli 83972], g... gi\|26110884, gi\|... - gi\|26250454\|ref\|NP_756494.1\| hypothetical protein c4636 [Escherichia coli CFT073], gi\|26110884\|gb\|AA...	157.0	[0..1]	[188..1]
gi\|77958170 - gi\|77958170\|ref\|ZP_00822208.1\| COG0431: Predicted flavoprotein [Yersinia bercovieri ATCC 43970]	157.0	[0..1]	[187..1]
gi\|110644055, gi... - gi\|110644055\|ref\|YP_671785.1\| hypothetical protein ECP_3913 [Escherichia coli 536], gi\|110345647\|gb\|... gi\|75242499, gi\|... - gi\|75242499\|ref\|ZP_00726243.1\| COG0431: Predicted flavoprotein [Escherichia coli F11], gi\|191170333\|...	157.0	[0..1]	[188..1]
gi\|224470173, gi... - gi\|224585645\|ref\|YP_002639444.1\| hypothetical protein SPC_3934 [Salmonella enterica subsp. enterica ... gi\|62182333, gi\|... - gi\|62182333\|ref\|YP_218750.1\| putative oxidoreductase [Salmonella enterica subsp. enterica serovar Ch...	156.0	[0..1]	[187..7]
gi\|40549313 - gi\|40549313\|gb\|AAR87716.1\| YieF [Salmonella enterica]	156.0	[0..1]	[187..7]
gi\|82546022, gi\|... - gi\|82546022\|ref\|YP_409969.1\| hypothetical protein SBO_3662 [Shigella boydii Sb227], gi\|81247433\|gb\|A...	156.0	[0..1]	[188..1]
gi\|205327036, gi... - gi\|205358190\|ref\|ZP_02576346.2\| YieF [Salmonella enterica subsp. enterica serovar 4,[5],12:i:- str. ... gi\|68132165 - gi\|68132165\|gb\|AAY85349.1\| putative oxidoreductase [Salmonella typhimurium DT104] gi\|16422423, gi\|... - gi\|16767134\|ref\|NP_462749.1\| putative oxidoreductase [Salmonella typhimurium LT2], gi\|16422423\|gb\|AA...	156.0	[0..1]	[187..7]

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Predicted Domain #1

Region A:
Residues: [1-188]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKLQVVTL LGSLRKGSFN GMVARTLPKI APASMEVNAL PSIADIPLYD ADVQQEEGFP  60
   61 ATVEALAEQI RQADGVVIVT PEYNYSVPGG LKNAIDWLSR LPDQPLAGKP VLIQTSSMGV 120
  121 IGGARCQYHL RQILVFLDAM VMNKPEFMGG VIQNKVDPQT GEVIDQGTLD HLTGQLTAFG 180
  181 EFIQRVKI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.0
Match:	1rttA
Description:	Crystal structure determination of a putative NADH-dependent reductase using sulfur anomalous signal
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.646071595570549	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: