YRC Public Data Repository - Protein Structure Prediction

Protein:	YIBK_ECOLI
Organism:	Escherichia coli
Length:	157 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIBK_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|207088581 - gi\|207088581\|gb\|EDZ65853.1\| RNA methyltransferase, TrmH family, group 2 [Nitrosococcus oceani AFC27] gi\|254435470, gi... - gi\|254435470\|ref\|ZP_05048977.1\| RNA methyltransferase, TrmH family, group 2 [Nitrosococcus oceani AF... gi\|77166275, gi\|... - gi\|77166275\|ref\|YP_344800.1\| RNA methyltransferase TrmH, group 2 [Nitrosococcus oceani ATCC 19707], ...	196.0	[0..1]	[151..1]
gi\|95108650, gi\|... - gi\|95108650\|emb\|CAK13344.1\| putative RNA methyltransferase, TrmH family, group 2 [Pseudomonas entomo... gi\|95108650 - gi\|95108650\|emb\|CAK13344.1\| putative RNA methyltransferase, TrmH family, group 2 [Pseudomonas entomo...	192.0	[0..1]	[152..1]
gi\|24986832, gi\|... - gi\|26991728\|ref\|NP_747153.1\| RNA methyltransferase [Pseudomonas putida KT2440], gi\|24986832\|gb\|AAN70...	191.0	[0..1]	[152..5]
gi\|34499838, gi\|... - gi\|34499838\|ref\|NP_904053.1\| RNA methyltransferase [Chromobacterium violaceum ATCC 12472], gi\|341056...	191.0	[0..1]	[154..1]
gi\|120325922, gi... - gi\|77952029\|ref\|ZP_00816447.1\| RNA methyltransferase TrmH, group 2 [Marinobacter aquaeolei VT8], gi\|...	191.0	[0..1]	[152..1]
gi\|81243247, gi\|... - gi\|82779099\|ref\|YP_405448.1\| putative tRNA/rRNA methyltransferase YibK [Shigella dysenteriae Sd197],...	191.0	[0..1]	[157..1]
tr\|I7BYZ6\|I7BYZ6... - tRNA (cytidine(34)-2'-O)-methyltransferase OS=Pseudomonas putida (strain DOT-T1E) GN=yibK PE=3 SV=1 tr\|E4RAH6\|E4RAH6... - tRNA (cytidine(34)-2'-O)-methyltransferase OS=Pseudomonas putida (strain BIRD-1) GN=trmL PE=3 SV=1 gi\|82716793, gi\|... - gi\|82736150\|ref\|ZP_00899010.1\| RNA methyltransferase TrmH, group 2 [Pseudomonas putida F1], gi\|82716...	191.0	[0..1]	[152..1]
gi\|194420665, gi... - gi\|83571399\|ref\|ZP_00922839.1\| COG0219: Predicted rRNA methylase (SpoU class) [Shigella dysenteriae ...	191.0	[0..1]	[157..1]
gi\|152985329, gi... - gi\|94417601\|ref\|ZP_01297418.1\| hypothetical protein PaerP_01000378 [Pseudomonas aeruginosa PA7], gi\|...	190.0	[0..1]	[153..1]
gi\|254671569 - gi\|254671569\|emb\|CBA09217.1\| hypothetical tRNA/rRNA methyltransferase [Neisseria meningitidis alpha1... gi\|11354139 - pir\|\|E81218 RNA methyltransferase, TrmH family NMB0268 [imported] - Neisseria meningitidis (strain M... gi\|15676192, gi\|... - gi\|7225492\|gb\|AAF40722.1\| RNA methyltransferase, TrmH family [Neisseria meningitidis MC58], gi\|15676... gi\|225106955, gi... - gi\|225106955\|ref\|ZP_03721091.1\| hypothetical protein NEILACOT_00370 [Neisseria lactamica ATCC 23970]...	190.0	[0..1]	[154..1]

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Predicted Domain #1

Region A:
Residues: [1-157]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNIVLYEPE IPPNTGNIIR LCANTGFRLH IIEPMGFAWD DKRLRRAGLD YHEFTAVTRH  60
   61 HDYRAFLEAE NPQRLFALTT KGTPAHSAVS YQDGDYLMFG PETRGLPASI LDALPAEQKI 120
  121 RIPMVPDSRS MNLSNAVSVV VYEAWRQLGY PGAVLRD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.522879
Match:	1j85A
Description:	Hypothetical tRNA/rRNA methyltransfease HI0766 (YibK homologue)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.77771076540343	bayes_pls_golite062009
methyltransferase activity	4.0901595540349	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.01958090893547	bayes_pls_golite062009
rRNA methyltransferase activity	3.659149846946	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.59156540645412	bayes_pls_golite062009
tRNA methyltransferase activity	2.52700462137917	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.29844424181442	bayes_pls_golite062009
tRNA (guanine-N1-)-methyltransferase activity	2.0947794364355	bayes_pls_golite062009
transferase activity	1.84002196534744	bayes_pls_golite062009
catalytic activity	1.16774040077235	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.47764353619615	bayes_pls_golite062009
N-methyltransferase activity	0.0655574594365502	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: