YRC Public Data Repository - Protein Structure Prediction

Protein:	YHDH_ECOLI
Organism:	Escherichia coli
Length:	324 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHDH_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|86134306, gi\|... - gi\|86134306\|ref\|ZP_01052888.1\| zinc-binding dehydrogenase [Polaribacter sp. MED152], gi\|85821169\|gb\|...	296.0	[0..1]	[323..12]
gi\|28872343, gi\|... - gi\|28872343\|ref\|NP_794962.1\| oxidoreductase, zinc-binding [Pseudomonas syringae pv. tomato str. DC30... tr\|Q87UR5\|Q87UR5... - Oxidoreductase, zinc-binding protein OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=PSPTO_523...	285.0	[0..1]	[324..1]
gi\|76160992 - gi\|76160992\|gb\|ABA40459.1\| NADPH quinone oxidoreductase-like protein [Solanum tuberosum]	284.0	[0..1]	[323..1]
gi\|71733591, gi\|... - gi\|71733591\|ref\|YP_272602.1\| quinone oxidoreductase [Pseudomonas syringae pv. phaseolicola 1448A], g...	282.0	[0..1]	[324..1]
gi\|15234529, gi\|... - pir\|\|T05166 quinone reductase homolog F18E5.200 - Arabidopsis thaliana, gi\|7268955\|emb\|CAB81265.1\| p...	281.0	[0..1]	[322..1]
gi\|2983768, gi\|1... - gi\|2983768\|gb\|AAC07327.1\| alcohol dehydrogenase [Aquifex aeolicus VF5], gi\|15606558\|ref\|NP_213938.1\|... gi\|7427649 - pir\|\|C70418 probable alcohol dehydrogenase (EC 1.1.1.-) - Aquifex aeolicus	279.0	[0..1]	[323..1]
gi\|77385669, gi\|... - gi\|77461666\|ref\|YP_351173.1\| zinc-containing alcohol dehydrogenase superfamily protein [Pseudomonas ...	279.0	[0..1]	[323..1]
gi\|68347561, gi\|... - gi\|70733262\|ref\|YP_263035.1\| oxidoreductase, zinc-binding [Pseudomonas fluorescens Pf-5], gi\|6834756...	277.0	[0..1]	[323..1]
gi\|84317897, gi\|... - gi\|84317897\|ref\|ZP_00966332.1\| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreduct... gi\|116053381, gi... - gi\|32044610\|ref\|ZP_00141711.1\| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreduct... gi\|107104336 - gi\|107104336\|ref\|ZP_01368254.1\| hypothetical protein PaerPA_01005411 [Pseudomonas aeruginosa PACS2]	277.0	[0..1]	[323..1]
gi\|63254289, gi\|... - gi\|66043582\|ref\|YP_233423.1\| zinc-containing alcohol dehydrogenase superfamily protein [Pseudomonas ...	277.0	[0..1]	[321..1]

Back

Predicted Domain #1

Region A:
Residues: [1-324]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQALLLEQQD GKTLASVQTL DESRLPEGDV TVDVHWSSLN YKDALAITGK GKIIRNFPMI  60
   61 PGIDFAGTVR TSEDPRFHAG QEVLLTGWGV GENHWGGLAE QARVKGDWLV AMPQGLDARK 120
  121 AMIIGTAGFT AMLCVMALED AGVRPQDGEI VVTGASGGVG STAVALLHKL GYQVVAVSGR 180
  181 ESTHEYLKSL GASRVLPRDE FAESRPLEKQ VWAGAIDTVG DKVLAKVLAQ MNYGGCVAAC 240
  241 GLAGGFTLPT TVMPFILRNV RLQGVDSVMT PPERRAQAWQ RLVADLPESF YTQAAKEISL 300
  301 SEAPNFAEAI INNQIQGRTL VKVN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.045757
Match:	1o89A
Description:	STRUCTURAL GENOMICS, UNKNOWN FUNCTION, CRYSTAL STRUCTURE OF E. COLI K-12 YHDH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	3.00069798806876	bayes_pls_golite062009
catalytic activity	2.16785883389468	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	1.88863369347022	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.3919444853018	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.27605103494323	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	1.09344283680379	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: