YRC Public Data Repository - Protein Structure Prediction

Protein:	YGFA_ECOLI
Organism:	Escherichia coli
Length:	182 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGFA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|71280724, gi\|... - gi\|71280724\|ref\|YP_270316.1\| 5-formyltetrahydrofolate cyclo-ligase family protein [Colwellia psychre...	229.0	[0..2]	[182..11]
gi\|59712711, gi\|... - gi\|59712711\|ref\|YP_205487.1\| ligase [Vibrio fischeri ES114], gi\|59480812\|gb\|AAW86599.1\| predicted li...	224.0	[0..3]	[182..12]
gi\|254230209, gi... - gi\|75853743\|ref\|ZP_00761514.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Vibrio sp. Ex25], gi\|...	223.0	[0..1]	[182..12]
gi\|84376740, gi\|... - gi\|84390086\|ref\|ZP_00991348.1\| putative 5-formyltetrahydrofolate cyclo-ligase-family protein [Vibrio...	222.0	[0..2]	[182..13]
gi\|192930785, gi... - gi\|193063508\|ref\|ZP_03044597.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli E22], gi\|... gi\|208725708, gi... - gi\|208805907\|ref\|ZP_03248244.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|189403793, gi... - gi\|189403793\|ref\|ZP_02785050.2\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|38704126 - gi\|38704126\|ref\|NP_311809.2\| putative ligase [Escherichia coli O157:H7] gi\|189404764, gi... - gi\|189404764\|ref\|ZP_02810768.2\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|209160736, gi... - gi\|209399336\|ref\|YP_002272387.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 ... gi\|217319900, gi... - gi\|217327533\|ref\|ZP_03443616.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|208735489, gi... - gi\|208814212\|ref\|ZP_03255541.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|208819943, gi... - gi\|208819943\|ref\|ZP_03260263.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|170018843, gi... - gi\|170018843\|ref\|YP_001723797.1\| putative ligase [Escherichia coli ATCC 8739], gi\|169753771\|gb\|ACA76... gi\|194424183, gi... - gi\|83587693\|ref\|ZP_00926320.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli 101-... gi\|189401951, gi... - gi\|189401951\|ref\|ZP_02778860.2\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|194415490, gi... - gi\|75212474\|ref\|ZP_00712498.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli B171... gi\|189402865, gi... - gi\|189402865\|ref\|ZP_02791915.2\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|75228579, gi\|... - gi\|75228579\|ref\|ZP_00715208.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli B7A]... gi\|188024584, gi... - gi\|188024584\|ref\|ZP_02772628.2\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|192959432, gi... - gi\|75239520\|ref\|ZP_00723491.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli E110... gi\|189010397, gi... - gi\|189010397\|ref\|ZP_03006309.1\| 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 s... gi\|38704126 - gi\|38704126\|ref\|NP_311809.2\| putative ligase [Escherichia coli O157:H7 str. Sakai] gi\|33347709\|ref\|... - putative ligase [Escherichia coli K12], putative ligase [Escherichia coli K12], 5-formyltetrahydrofo...	221.0	[0..1]	[182..19]
gi\|229774937 - gi\|229774937\|ref\|YP_690333.2\| putative ligase [Shigella flexneri 5 str. 8401] gi\|30064222, gi\|... - gi\|30064222\|ref\|NP_838393.1\| putative ligase [Shigella flexneri 2a str. 2457T], gi\|30042479\|gb\|AAP18... gi\|56383750, gi\|... - gi\|56480199\|ref\|NP_708674.2\| putative ligase [Shigella flexneri 2a str. 301], gi\|56383750\|gb\|AAN4438...	221.0	[0..1]	[182..1]
gi\|75178804 - gi\|75178804\|ref\|ZP_00698840.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Shigella boydii BS512...	221.0	[0..1]	[182..1]
gi\|25302307 - gi\|25302307\|pir\|\|B85947 probable ligase ygfA [imported] - Escherichia coli (strain O157:H7, substrai... gi\|15803446, gi\|... - gi\|15803446\|ref\|NP_289479.1\| putative ligase [Escherichia coli O157:H7 EDL933], gi\|12517441\|gb\|AAG58...	220.0	[0..1]	[182..1]
gi\|253978890, gi... - gi\|254289583\|ref\|YP_003055331.1\| predicted ligase [Escherichia coli BL21(DE3)], gi\|253978890\|gb\|ACT4... gi\|254162823, gi... - gi\|254162823\|ref\|YP_003045931.1\| predicted ligase [Escherichia coli B str. REL606], gi\|253974724\|gb\|... gi\|242378442, gi... - gi\|251786169\|ref\|YP_003000473.1\| hypothetical protein B21_02706 [Escherichia coli BL21], gi\|24237844... gi\|229560212 - gi\|229560212\|ref\|YP_670789.2\| putative ligase [Escherichia coli 536] gi\|75515305 - gi\|75515305\|ref\|ZP_00737489.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli 5363... gi\|75196863, gi\|... - gi\|75196863\|ref\|ZP_00706933.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli HS],...	220.0	[0..1]	[182..1]
gi\|75187627, gi\|... - gi\|75187627\|ref\|ZP_00700894.1\| COG0212: 5-formyltetrahydrofolate cyclo-ligase [Escherichia coli E243...	220.0	[0..1]	[182..1]

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Predicted Domain #1

Region A:
Residues: [1-182]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRQRRRALT PEQQQEMGQQ AATRMMTYPP VVMAHTVAVF LSFDGELDTQ PLIEQLWRAG  60
   61 KRVYLPVLHP FSAGNLLFLN YHPQSELVMN RLKIHEPKLD VRDVLPLSRL DVLITPLVAF 120
  121 DEYGQRLGMG GGFYDRTLQN WQHYKTQPVG YAHDCQLVEK LPVEEWDIPL PAVVTPSKVW 180
  181 EW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.69897
Match:	1ydmA
Description:	X-Ray structure of Northeast Structural Genomics target SR44
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits