YRC Public Data Repository - Protein Structure Prediction

Protein:	YGDL_ECOLI
Organism:	Escherichia coli
Length:	268 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGDL_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|91203467 - gi\|91203467\|emb\|CAJ71120.1\| strongly similar to molybdopterin synthesis protein MoeB and thiamin bio...	277.0	[0..1]	[265..1]
gi\|83756702, gi\|... - gi\|83815308\|ref\|YP_446148.1\| MoeZ/MoeB domain-contain protein [Salinibacter ruber DSM 13855], gi\|837...	276.0	[0..3]	[249..13]
gi\|76800681, gi\|... - gi\|76800681\|ref\|YP_325689.1\| molybdenum cofactor biosynthesis protein MoeB [Natronomonas pharaonis D...	269.0	[0..1]	[249..1]
gi\|114777472, gi... - gi\|114777472\|ref\|ZP_01452469.1\| molybdopterin biosynthesis protein MoeB [Mariprofundus ferrooxydans ...	269.0	[0..6]	[249..5]
gi\|117928984, gi... - gi\|88931318\|ref\|ZP_01137012.1\| Rhodanese-like [Acidothermus cellulolyticus 11B], gi\|88912597\|gb\|EAR3...	268.0	[0..2]	[265..10]
gi\|83590802, gi\|... - gi\|83590802\|ref\|YP_430811.1\| UBA/THIF-type NAD/FAD binding fold [Moorella thermoacetica ATCC 39073],...	266.0	[0..3]	[249..1]
gi\|106891733, gi... - gi\|148654884\|ref\|YP_001275089.1\| UBA/THIF-type NAD/FAD binding protein [Roseiflexus sp. RS-1], gi\|14...	266.0	[0..3]	[249..4]
gi\|45545541, gi\|... - gi\|68563155\|ref\|ZP_00602357.1\| UBA/THIF-type NAD/FAD binding fold:Rhodanese-like:MoeZ/MoeB [Rubrobac...	266.0	[0..4]	[265..14]
gi\|222526984, gi... - gi\|222526984\|ref\|YP_002571455.1\| UBA/THIF-type NAD/FAD binding protein [Chloroflexus sp. Y-400-fl], ... gi\|53796678 - ref\|ZP_00020762.2\| COG0476: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine bi... gi\|163849021, gi... - gi\|76258733\|ref\|ZP_00766387.1\| UBA/THIF-type NAD/FAD binding fold:Rhodanese-like:MoeZ/MoeB [Chlorofl...	266.0	[0..1]	[249..1]
gi\|39996452, gi\|... - gi\|39996452\|ref\|NP_952403.1\| thiF family protein [Geobacter sulfurreducens PCA], gi\|39983332\|gb\|AAR3...	266.0	[0..4]	[249..1]

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Predicted Domain #1

Region A:
Residues: [1-268]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVVISDAWR QRFGGTARLY GEKALQLFAD AHICVVGIGG VGSWAAEALA RTGIGAITLI  60
   61 DMDDVCVTNT NRQIHALRDN VGLAKAEVMA ERIRQINPEC RVTVVDDFVT PDNVAQYMSV 120
  121 GYSYVIDAID SVRPKAALIA YCRRNKIPLV TTGGAGGQID PTQIQVTDLA KTIQDPLAAK 180
  181 LRERLKSDFG VVKNSKGKLG VDCVFSTEAL VYPQSDGTVC AMKATAEGPK RMDCASGFGA 240
  241 ATMVTATFGF VAVSHALKKM MAKAARQG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.522879
Match:	1jw9B
Description:	Molybdenum cofactor biosynthesis protein MoeB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
small protein activating enzyme activity	1.61603220653307	bayes_pls_golite062009
catalytic activity	1.59245438598251	bayes_pls_golite062009
URM1 activating enzyme activity	0.936791644743361	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: