YRC Public Data Repository - Protein Structure Prediction

Protein:	YGBL_ECOLI
Organism:	Escherichia coli
Length:	212 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGBL_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|84378564, gi\|... - gi\|84386459\|ref\|ZP_00989486.1\| hypothetical protein V12B01_17296 [Vibrio splendidus 12B01], gi\|84378...	230.0	[0..1]	[211..1]
gi\|215488055, gi... - gi\|215488055\|ref\|YP_002330486.1\| putative aldolase [Escherichia coli O127:H6 str. E2348/69], gi\|2152... gi\|26249138, gi\|... - gi\|26249138\|ref\|NP_755178.1\| putative aldolase [Escherichia coli CFT073], gi\|26109545\|gb\|AAN81748.1\|... gi\|227834547, gi... - gi\|227888278\|ref\|ZP_04006083.1\| aldolase [Escherichia coli 83972], gi\|227834547\|gb\|EEJ45013.1\| aldol...	225.0	[0..1]	[212..1]
gi\|110642876, gi... - gi\|110642876\|ref\|YP_670606.1\| putative aldolase [Escherichia coli 536], gi\|110344468\|gb\|ABG70705.1\| ... gi\|75241873, gi\|... - gi\|75241873\|ref\|ZP_00725692.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ...	225.0	[0..1]	[212..1]
gi\|91212101, gi\|... - gi\|91212101\|ref\|YP_542087.1\| putative aldolase [Escherichia coli UTI89], gi\|91073675\|gb\|ABE08556.1\| ... gi\|226899676, gi... - gi\|237706636\|ref\|ZP_04537117.1\| aldolase class II protein YgbL [Escherichia sp. 3_2_53FAA], gi\|22689... gi\|218559729, gi... - gi\|218559729\|ref\|YP_002392642.1\| putative aldolase [Escherichia coli S88], gi\|218366498\|emb\|CAR04250... gi\|117624971, gi... - gi\|117624971\|ref\|YP_853959.1\| putative aldolase [Escherichia coli APEC O1], gi\|115514095\|gb\|ABJ02170...	224.0	[0..1]	[212..1]
gi\|37526401, gi\|... - gi\|37526401\|ref\|NP_929745.1\| putative aldolase [Photorhabdus luminescens subsp. laumondii TTO1], gi\|...	216.0	[0..6]	[212..7]
gi\|46156402, gi\|... - gi\|46156402\|ref\|ZP_00132853.2\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ...	216.0	[0..6]	[211..1]
gi\|77979837 - gi\|77979837\|ref\|ZP_00835253.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ...	215.0	[0..6]	[212..1]
gi\|112822206, gi... - gi\|53692388\|ref\|ZP_00347243.1\| COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and ...	214.0	[0..6]	[211..1]
gi\|224469221, gi... - gi\|224584694\|ref\|YP_002638492.1\| hypothetical protein SPC_2958 [Salmonella enterica subsp. enterica ... gi\|204928064, gi... - gi\|204928064\|ref\|ZP_03219264.1\| aldolase class II protein YgbL [Salmonella enterica subsp. enterica ... gi\|199604068, gi... - gi\|200386970\|ref\|ZP_03213582.1\| aldolase class II protein YgbL [Salmonella enterica subsp. enterica ... gi\|62129049, gi\|... - gi\|62181416\|ref\|YP_217833.1\| putative aldolase [Salmonella enterica subsp. enterica serovar Cholerae... gi\|197936803, gi... - gi\|198242287\|ref\|YP_002216882.1\| aldolase class II protein YgbL [Salmonella enterica subsp. enterica... gi\|197251049, gi... - gi\|197251049\|ref\|YP_002147811.1\| aldolase class II protein YgbL [Salmonella enterica subsp. enterica... gi\|194710056, gi... - gi\|194734554\|ref\|YP_002115865.1\| aldolase class II protein YgbL [Salmonella enterica subsp. enterica... gi\|168261956, gi... - gi\|205349101\|gb\|EDZ35732.1\| aldolase class II protein YgbL [Salmonella enterica subsp. enterica sero... gi\|168235954, gi... - gi\|197290766\|gb\|EDY30120.1\| aldolase class II protein YgbL [Salmonella enterica subsp. enterica sero... gi\|238909684 - gi\|238909684\|ref\|ZP_04653521.1\| putative aldolase [Salmonella enterica subsp. enterica serovar Tenne... gi\|167550233, gi... - gi\|205324752\|gb\|EDZ12591.1\| aldolase class II protein YgbL [Salmonella enterica subsp. enterica sero... gi\|161615837, gi... - gi\|161615837\|ref\|YP_001589802.1\| putative aldolase [Salmonella enterica subsp. enterica serovar Para...	214.0	[0..1]	[211..1]
gi\|150839530, gi... - gi\|75429206\|ref\|ZP_00732142.1\| ribulose-5-phosphate 4-epimerase and related epimerases and aldolases...	214.0	[0..6]	[211..1]

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Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDFAKVEQS LREEMTRIAS SFFQRGYATG SAGNLSLLLP DGNLLATPTG SCLGNLDPQR  60
   61 LSKVAADGEW LSGDKPSKEV LFHLALYRNN PRCKAVVHLH STWSTALSCL QGLDSSNVIR 120
  121 PFTPYVVMRM GNVPLVPYYR PGDKRIAQDL AELAADNQAF LLANHGPVVC GESLQEAANN 180
  181 MEELEETAKL IFILGDRPIR YLTAGEIAEL RS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.522879
Match:	1dzvP
Description:	L-fuculose-1-phosphate aldolase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
L-ribulose-phosphate 4-epimerase activity	3.50507333471987	bayes_pls_golite062009
L-fuculose-phosphate aldolase activity	2.43949811564444	bayes_pls_golite062009
catalytic activity	1.9511172460719	bayes_pls_golite062009
aldehyde-lyase activity	1.08084403816388	bayes_pls_golite062009
racemase and epimerase activity, acting on carbohydrates and derivatives	0.42493443904865	bayes_pls_golite062009
racemase and epimerase activity	0.15063402811264	bayes_pls_golite062009
isomerase activity	0.0458367676418101	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: