YRC Public Data Repository - Protein Structure Prediction

Protein:	YFCE_ECOLI
Organism:	Escherichia coli
Length:	184 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFCE_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|52695570, gi\|... - gi\|52695571\|pdb\|1SU1\|D Chain D, Structural And Biochemical Characterization Of Yfce, A Phosphoestera...	158.0	[0..1]	[184..25]
gi\|82777708, gi\|... - gi\|82777708\|ref\|YP_404057.1\| phosphodiesterase [Shigella dysenteriae Sd197], gi\|81241856\|gb\|ABB62566...	156.0	[0..1]	[184..1]
gi\|91073170, gi\|... - gi\|91211596\|ref\|YP_541582.1\| phosphodiesterase [Escherichia coli UTI89], gi\|91073170\|gb\|ABE08051.1\| ... gi\|117624490, gi... - gi\|117624490\|ref\|YP_853403.1\| phosphodiesterase [Escherichia coli APEC O1], gi\|115513614\|gb\|ABJ01689... gi\|218365982, gi... - gi\|218559213\|ref\|YP_002392126.1\| phosphodiesterase [Escherichia coli S88], gi\|218365982\|emb\|CAR03726... gi\|226901143, gi... - gi\|237704777\|ref\|ZP_04535258.1\| phosphodiesterase [Escherichia sp. 3_2_53FAA], gi\|226901143\|gb\|EEH87... gi\|218428024, gi... - gi\|218690460\|ref\|YP_002398672.1\| phosphodiesterase [Escherichia coli ED1a], gi\|218428024\|emb\|CAR0894...	155.0	[0..1]	[184..1]
gi\|188017233, gi... - gi\|188017233\|gb\|EDU55355.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC4113], g... gi\|189357614, gi... - gi\|189357614\|gb\|EDU76033.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC4401], g... gi\|38704073 - gi\|38704073\|ref\|NP_311211.2\| phosphodiesterase [Escherichia coli O157:H7] gi\|253772776, gi... - gi\|253772776\|ref\|YP_003035607.1\| phosphodiesterase, MJ0936 family [Escherichia coli BL21(DE3)], gi\|2... gi\|194418882, gi... - gi\|83570146\|ref\|ZP_00921593.1\| COG0622: Predicted phosphoesterase [Shigella dysenteriae 1012], gi\|19... gi\|227887359, gi... - gi\|227887359\|ref\|ZP_04005164.1\| phosphodiesterase [Escherichia coli 83972], gi\|227835709\|gb\|EEJ46175... gi\|208813732, gi... - gi\|208813732\|ref\|ZP_03255061.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC4045... gi\|208741784, gi... - gi\|208821661\|ref\|ZP_03261981.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC4042... gi\|195935679 - gi\|195935679\|ref\|ZP_03081061.1\| phosphodiesterase [Escherichia coli O157:H7 str. EC4024] gi\|208729346, gi... - gi\|208809545\|ref\|ZP_03251882.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC4206... gi\|215265585, gi... - gi\|215487513\|ref\|YP_002329944.1\| phosphodiesterase [Escherichia coli O127:H6 str. E2348/69], gi\|2152... gi\|38704073 - gi\|38704073\|ref\|NP_311211.2\| phosphodiesterase [Escherichia coli O157:H7 str. Sakai] gi\|217327126, gi... - gi\|217327126\|ref\|ZP_03443209.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. TW1458... gi\|110344096, gi... - gi\|110642504\|ref\|YP_670234.1\| phosphodiesterase [Escherichia coli 536], gi\|110344096\|gb\|ABG70333.1\| ... gi\|209400493, gi... - gi\|209400493\|ref\|YP_002271709.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC411... gi\|209919749, gi... - gi\|209919749\|ref\|YP_002293833.1\| phosphodiesterase [Escherichia coli SE11], gi\|209913008\|dbj\|BAG7808... gi\|168772971, gi... - gi\|187771082\|gb\|EDU34926.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC4196], g... gi\|168780158, gi... - gi\|189002083\|gb\|EDU71069.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC4076], g... gi\|189368220, gi... - gi\|189368220\|gb\|EDU86636.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC4501], g... gi\|189362981, gi... - gi\|189362981\|gb\|EDU81400.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC4486], g... gi\|170019391, gi... - gi\|170019391\|ref\|YP_001724345.1\| phosphodiesterase [Escherichia coli ATCC 8739], gi\|169754319\|gb\|ACA... gi\|170680770, gi... - gi\|170680770\|ref\|YP_001744500.1\| phosphodiesterase [Escherichia coli SMS-3-5], gi\|170518488\|gb\|ACB16... gi\|189372951, gi... - gi\|189372951\|gb\|EDU91367.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC869], gi... gi\|189379031, gi... - gi\|189379031\|gb\|EDU97447.1\| phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC508], gi... gi\|75259758, gi\|... - gi\|75259758\|ref\|ZP_00731060.1\| COG0622: Predicted phosphoesterase [Escherichia coli E22], gi\|1930622... gi\|75515665, gi\|... - gi\|75515665\|ref\|ZP_00737800.1\| COG0622: Predicted phosphoesterase [Escherichia coli 53638], gi\|18849... gi\|33347644\|ref\|... - hypothetical protein b2300 [Escherichia coli K12], hypothetical protein b2300 [Escherichia coli K12]... gi\|83588283, gi\|... - gi\|83588283\|ref\|ZP_00926908.1\| COG0622: Predicted phosphoesterase [Escherichia coli 101-1], gi\|19443... gi\|187427633, gi... - gi\|75177912\|ref\|ZP_00697974.1\| COG0622: Predicted phosphoesterase [Shigella boydii BS512], gi\|187730... gi\|75187082, gi\|... - gi\|75187082\|ref\|ZP_00700349.1\| COG0622: Predicted phosphoesterase [Escherichia coli E24377A], gi\|157... gi\|157161788, gi... - gi\|75196343\|ref\|ZP_00706413.1\| COG0622: Predicted phosphoesterase [Escherichia coli HS], gi\|15716178... gi\|75209287, gi\|... - gi\|75209287\|ref\|ZP_00709527.1\| COG0622: Predicted phosphoesterase [Escherichia coli B171], gi\|194429... gi\|190903482, gi... - gi\|75230318\|ref\|ZP_00716808.1\| COG0622: Predicted phosphoesterase [Escherichia coli B7A], gi\|1911665... gi\|193068176, gi... - gi\|75238083\|ref\|ZP_00722088.1\| COG0622: Predicted phosphoesterase [Escherichia coli E110019], gi\|193... gi\|75243111, gi\|... - gi\|75243111\|ref\|ZP_00726817.1\| COG0622: Predicted phosphoesterase [Escherichia coli F11], gi\|1911701...	152.0	[0..2]	[184..1]
gi\|16420889, gi\|... - gi\|16765674\|ref\|NP_461289.1\| phosphodiesterase [Salmonella typhimurium LT2], gi\|16420889\|gb\|AAL21248... gi\|29136657, gi\|... - gi\|29141032\|ref\|NP_804374.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Typhi st... gi\|16503571, gi\|... - gi\|25528254\|pir\|\|AI0799 conserved hypothetical protein STY2577 [imported] - Salmonella enterica subs... gi\|16761272 - gi\|16761272\|ref\|NP_456889.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Typhi st... gi\|194409168, gi... - gi\|194450864\|ref\|YP_002046402.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Heid... gi\|194736823, gi... - gi\|194736823\|ref\|YP_002115417.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar... gi\|197213241, gi... - gi\|197249538\|ref\|YP_002147307.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar... gi\|238912373 - gi\|238912373\|ref\|ZP_04656210.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Tenne... gi\|197241517, gi... - gi\|197263262\|ref\|ZP_03163336.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar ... gi\|168261631, gi... - gi\|205349626\|gb\|EDZ36257.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar Hada... gi\|168465944, gi... - gi\|195631316\|gb\|EDX49876.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar Newp... gi\|168817917, gi... - gi\|205344924\|gb\|EDZ31688.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar Welt... gi\|194403902, gi... - gi\|194445239\|ref\|YP_002041610.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar... gi\|167549648, gi... - gi\|205325274\|gb\|EDZ13113.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar Sain... gi\|205328790, gi... - gi\|205328790\|gb\|EDZ15554.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar 4,[5... gi\|197289639, gi... - gi\|197289639\|gb\|EDY29002.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar Schw... gi\|205338674, gi... - gi\|205338674\|gb\|EDZ25438.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar Heid... gi\|161612920, gi... - gi\|161612920\|ref\|YP_001586885.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Para... gi\|214002021 - gi\|214002021\|ref\|ZP_03412756.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|224467692, gi... - gi\|224583165\|ref\|YP_002636963.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Para... lcl\|NC_016856.1_... - [gene=yfcE] [protein=phosphodiesterase] [protein_id=YP_005238428.1] [location=complement(2510571..25... gi\|213618926 - gi\|213618926\|ref\|ZP_03372752.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|213649617 - gi\|213649617\|ref\|ZP_03379670.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|213857822 - gi\|213857822\|ref\|ZP_03384793.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|213982338 - gi\|213982338\|ref\|ZP_03409597.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|207857765, gi... - gi\|207857765\|ref\|YP_002244416.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Ente... gi\|213026768 - gi\|213026768\|ref\|ZP_03341215.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|213052562 - gi\|213052562\|ref\|ZP_03345440.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|213426995 - gi\|213426995\|ref\|ZP_03359745.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Typhi... gi\|197361690, gi... - gi\|197361690\|ref\|YP_002141326.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Para... gi\|198242795, gi... - gi\|198242795\|ref\|YP_002216419.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar... gi\|62180918, gi\|... - gi\|62180918\|ref\|YP_217335.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Cholerae... gi\|204928916, gi... - gi\|204928916\|ref\|ZP_03220059.1\| phosphodiesterase YfcE [Salmonella enterica subsp. enterica serovar ... gi\|56412756, gi\|... - gi\|56412756\|ref\|YP_149831.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Paratyph... gi\|205353462, gi... - gi\|205353462\|ref\|YP_002227263.1\| phosphodiesterase [Salmonella enterica subsp. enterica serovar Gall...	149.0	[0..2]	[183..1]
gi\|30041981, gi\|... - gi\|30063726\|ref\|NP_837897.1\| phosphodiesterase [Shigella flexneri 2a str. 2457T], gi\|30041981\|gb\|AAP... gi\|56480087, gi\|... - gi\|56480087\|ref\|NP_708182.2\| phosphodiesterase [Shigella flexneri 2a str. 301], gi\|56383638\|gb\|AAN43... gi\|110806263, gi... - gi\|110806263\|ref\|YP_689783.1\| phosphodiesterase [Shigella flexneri 5 str. 8401], gi\|110615811\|gb\|ABF...	147.0	[0..2]	[184..1]
gi\|169750319, gi... - gi\|170023785\|ref\|YP_001720290.1\| phosphodiesterase [Yersinia pseudotuberculosis YPIII], gi\|169750319... gi\|167051534, gi... - gi\|167399030\|ref\|ZP_02304554.1\| phosphodiesterase, MJ0936 family [Yersinia pestis biovar Antiqua str... gi\|108808057, gi... - gi\|108808057\|ref\|YP_651973.1\| phosphodiesterase [Yersinia pestis Antiqua], gi\|108779970\|gb\|ABG14028.... gi\|153948860, gi... - gi\|153948860\|ref\|YP_001400413.1\| phosphodiesterase [Yersinia pseudotuberculosis IP 31758], gi\|152960... gi\|186896003, gi... - gi\|186896003\|ref\|YP_001873115.1\| phosphodiesterase [Yersinia pseudotuberculosis PB1/+], gi\|186699029... gi\|162352525, gi... - gi\|162419710\|ref\|YP_001604955.1\| phosphodiesterase [Yersinia pestis Angola], gi\|162352525\|gb\|ABX8647... gi\|51590205, gi\|... - gi\|51596923\|ref\|YP_071114.1\| phosphodiesterase [Yersinia pseudotuberculosis IP 32953], gi\|51590205\|e... Q668Y3\|Q668Y3_YERPS - Putative uncharacterized protein - Yersinia pseudotuberculosis	145.0	[0..2]	[182..1]
gi\|50121966, gi\|... - gi\|50121966\|ref\|YP_051133.1\| phosphodiesterase [Pectobacterium atrosepticum SCRI1043], gi\|49612492\|e...	144.0	[0..2]	[182..1]
gi\|4760827 - gi\|4760827\|dbj\|BAA77455.1\| unnamed protein product [Clostridium histolyticum]	142.0	[0..2]	[178..1]
gi\|28211458, gi\|... - gi\|28211458\|ref\|NP_782402.1\| phosphodiesterase [Clostridium tetani E88], gi\|28203899\|gb\|AAO36339.1\| ...	142.0	[0..2]	[176..1]

Back

Predicted Domain #1

Region A:
Residues: [1-184]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKLMFASDI HGSLPATERV LELFAQSGAQ WLVILGDVLN HGPRNALPEG YAPAKVAERL  60
   61 NEVAHKVIAV RGNCDSEVDQ MLLHFPITAP WQQVLLEKQR LFLTHGHLFG PENLPALNQN 120
  121 DVLVYGHTHL PVAEQRGEIF HFNPGSVSIP KGGNPASYGM LDNDVLSVIA LNDQSIIAQV 180
  181 AINP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.045757
Match:	1su1A
Description:	Structural and biochemical characterization of Yfce, a phosphoesterase from E. coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39852585255405	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.823602828994992	bayes_pls_golite062009
hydrolase activity	0.74139737510837	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.693201478742451	bayes_pls_golite062009
phosphatase activity	0.577496277405656	bayes_pls_golite062009
phosphoprotein phosphatase activity	0.370016286315163	bayes_pls_golite062009
protein serine/threonine phosphatase activity	0.228664868657767	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: