YRC Public Data Repository - Protein Structure Prediction

Protein:	YEFM_ECOLI
Organism:	Escherichia coli
Length:	83 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YEFM_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|24113402, gi\|... - gi\|24113402\|ref\|NP_707912.1\| antitoxin YefM [Shigella flexneri 2a str. 301], gi\|24052422\|gb\|AAN43619... gi\|30063468, gi\|... - gi\|30063468\|ref\|NP_837639.1\| antitoxin YefM [Shigella flexneri 2a str. 2457T], gi\|30041721\|gb\|AAP174... YEFM_SHIFL - Antitoxin YefM OS=Shigella flexneri GN=yefM PE=3 SV=1 gi\|110805991, gi... - gi\|110805991\|ref\|YP_689511.1\| antitoxin YefM [Shigella flexneri 5 str. 8401], gi\|110615539\|gb\|ABF042...	105.0	[0..1]	[83..1]
gi\|75766065, gi\|... - gi\|75766067\|pdb\|2A6Q\|D Chain D, Crystal Structure Of Yefm-Yoeb Complex, gi\|75766066\|pdb\|2A6Q\|C Chain...	103.0	[0..1]	[83..4]
gi\|77384858, gi\|... - gi\|77460855\|ref\|YP_350362.1\| prevent-host-death protein [Pseudomonas fluorescens Pf0-1], gi\|77384858...	103.0	[0..1]	[83..24]
gi\|87120886, gi\|... - gi\|87120886\|ref\|ZP_01076778.1\| hypothetical protein MED121_09765 [Marinomonas sp. MED121], gi\|861637...	102.0	[0..1]	[83..1]
gi\|26248392, gi\|... - gi\|26248392\|ref\|NP_754432.1\| Hypothetical protein yefM [Escherichia coli CFT073], gi\|26108796\|gb\|AAN... gi\|227887067, gi... - gi\|227887067\|ref\|ZP_04004872.1\| prevent-host-death family protein [Escherichia coli 83972], gi\|22783... gi\|91072878, gi\|... - gi\|91211304\|ref\|YP_541290.1\| hypothetical protein YefM [Escherichia coli UTI89], gi\|91072878\|gb\|ABE0... gi\|75514059 - gi\|75514059\|ref\|ZP_00736389.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c...	102.0	[0..1]	[83..10]
gi\|75196085 - gi\|75196085\|ref\|ZP_00706155.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|75210038 - gi\|75210038\|ref\|ZP_00710221.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|7467161 - gi\|7467161\|pir\|\|H64966 yefM protein - Escherichia coli (strain K-12) gi\|75229121 - gi\|75229121\|ref\|ZP_00715696.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|1788328, gi\|1... - gb\|AAC75078.1\| orf, hypothetical protein; conserved hypothetical protein [Escherichia coli K12], gi... gi\|75259167 - gi\|75259167\|ref\|ZP_00730515.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c... gi\|117624221, gi... - gi\|117624221\|ref\|YP_853134.1\| antitoxin YefM [Escherichia coli APEC O1], gi\|115513345\|gb\|ABJ01420.1\|... gi\|82543394, gi\|... - gi\|82543394\|ref\|YP_407341.1\| hypothetical protein SBO_0843 [Shigella boydii Sb227], gi\|81244805\|gb\|A... gi\|237704475, gi... - gi\|237704475\|ref\|ZP_04534956.1\| antitoxin YefM [Escherichia sp. 3_2_53FAA], gi\|226900841\|gb\|EEH87100... gi\|75177145 - gi\|75177145\|ref\|ZP_00697243.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Shigella boyd... gi\|75186825 - gi\|75186825\|ref\|ZP_00700092.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Escherichia c...	101.0	[0..1]	[83..10]
gi\|30248721, gi\|... - gi\|30248721\|ref\|NP_840791.1\| hypothetical protein NE0712 [Nitrosomonas europaea ATCC 19718], gi\|3018...	100.0	[0..1]	[83..16]
gi\|83363046, gi\|... - gi\|83367492\|ref\|ZP_00912361.1\| Prevent-host-death protein [Rhodobacter sphaeroides ATCC 17025], gi\|8...	100.0	[0..1]	[83..33]
gi\|121997585, gi... - gi\|88950060\|ref\|ZP_01152672.1\| Prevent-host-death protein [Halorhodospira halophila SL1], gi\|8892661...	100.0	[0..1]	[83..1]
gi\|126097534, gi... - gi\|126208742\|ref\|YP_001053967.1\| antitoxin YefM [Actinobacillus pleuropneumoniae L20], gi\|126097534\|... gi\|46143500 - gi\|46143500\|ref\|ZP_00204491.1\| COG2161: Antitoxin of toxin-antitoxin stability system [Actinobacillu...	99.0	[0..1]	[83..1]

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Predicted Domain #1

Region A:
Residues: [1-83]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTISYSEAR QNLSATMMKA VEDHAPILIT RQNGEACVLM SLEEYNSLEE TAYLLRSPAN  60
   61 ARRLMDSIDS LKSGKGTEKD IIE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.0
Match:	2a6qA
Description:	Crystal structure of YefM-YoeB complex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits