YRC Public Data Repository - Protein Structure Prediction

Protein:	YEAM_ECOLI
Organism:	Escherichia coli
Length:	273 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YEAM_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|81241099, gi\|... - gi\|82776951\|ref\|YP_403300.1\| putative ARAC-type regulatory protein [Shigella dysenteriae Sd197], gi\|...	184.0	[0..1]	[273..1]
gi\|110641911, gi... - gi\|110641911\|ref\|YP_669641.1\| transcriptional regulator YeaM [Escherichia coli 536], gi\|110343503\|gb... gi\|227837355, gi... - gi\|227885782\|ref\|ZP_04003587.1\| transcriptional regulator YeaM [Escherichia coli 83972], gi\|22783735... gi\|215265078, gi... - gi\|215487006\|ref\|YP_002329437.1\| predicted DNA-binding transcriptional regulator, ARAC-type [Escheri... gi\|26248049, gi\|... - gi\|26248049\|ref\|NP_754089.1\| putative transcriptional regulator YeaM [Escherichia coli CFT073], gi\|2...	183.0	[0..1]	[273..1]
gi\|74311898, gi\|... - gi\|74311898\|ref\|YP_310317.1\| putative ARAC-type regulatory protein [Shigella sonnei Ss046], gi\|73855... gi\|82543812, gi\|... - gi\|82543812\|ref\|YP_407759.1\| putative ARAC-type regulatory protein [Shigella boydii Sb227], gi\|81245... gi\|218695349, gi... - gi\|218695349\|ref\|YP_002403016.1\| putative DNA-binding transcriptional regulator [Escherichia coli 55... gi\|209919152, gi... - gi\|209919152\|ref\|YP_002293236.1\| putative regulator [Escherichia coli SE11], gi\|209912411\|dbj\|BAG774...	183.0	[0..1]	[273..1]
gi\|89074223, gi\|... - gi\|89074223\|ref\|ZP_01160713.1\| putative transcriptional regulator [Photobacterium sp. SKA34], gi\|890...	183.0	[0..1]	[259..1]
gi\|90439553, gi\|... - gi\|90578720\|ref\|ZP_01234530.1\| putative transcriptional regulator [Vibrio angustum S14], gi\|90439553...	182.0	[0..1]	[259..1]
gi\|117623958, gi... - gi\|117623958\|ref\|YP_852871.1\| putative transcriptional regulator [Escherichia coli APEC O1], gi\|1155... gi\|237705741, gi... - gi\|237705741\|ref\|ZP_04536222.1\| transcriptional regulator YeaM [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|218365426, gi... - gi\|218558657\|ref\|YP_002391570.1\| putative DNA-binding transcriptional regulator [Escherichia coli S8... gi\|218427294, gi... - gi\|218689730\|ref\|YP_002397942.1\| putative DNA-binding transcriptional regulator [Escherichia coli ED... gi\|91072581, gi\|... - gi\|91211007\|ref\|YP_540993.1\| transcriptional regulator YeaM [Escherichia coli UTI89], gi\|91072581\|gb...	181.0	[0..1]	[273..1]
gi\|194418273, gi... - gi\|83569600\|ref\|ZP_00921051.1\| COG2207: AraC-type DNA-binding domain-containing proteins [Shigella d...	180.0	[0..1]	[273..1]
gi\|67666232, gi\|... - gi\|67666232\|ref\|ZP_00463483.1\| Helix-turn-helix, AraC type:Arac protein, arabinose-binding/dimerisat... gi\|134137249, gi... - gi\|67545925\|ref\|ZP_00423843.1\| Helix-turn-helix, AraC type:Arac protein, arabinose-binding/dimerisat...	178.0	[0..4]	[256..12]

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Predicted Domain #1

Region A:
Residues: [1-97]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMHRLNLNGY EPDRHHEAAV AFCIHAGTDE LTSPVHQHRK GQLILALHGA ITCTVENALW  60
   61 MVPPQYAVWI PGGVEHSNQV TANAELCFLF IEPSAVT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.0
Match:	2f4pA
Description:	Crystal structure of hypothetical protein (tm1010) from THERMOTOGA MARITIMA at 1.90 A resolution
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [98-273]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTTCCTLKI SPLCRELILT LANRTTTQRA EPMTRRLIQV LFDELPQQPQ QQLHLPVSSH  60
   61 PKIRTMVEMM AKGPVEWGAL GQWAGFFAMS ERNLARLIVK ETGLSFRQWR QQLQLIMALQ 120
  121 GLVKGDTVQK VAHTLGYDST TAFITMFKKG LGQTPGRYIA RLTTVSPQSA KPDPRQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.09691
Match:	1wpkA
Description:	Methylated Form of N-terminal Transcriptional Regulator Domain of Escherichia Coli Ada Protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits