YRC Public Data Repository - Protein Structure Prediction

Protein:	YEAB_ECOLI
Organism:	Escherichia coli
Length:	192 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YEAB_ECOLI.

Description	E-value	Query Range	Subject Range
NUDL_SALPA - Uncharacterized Nudix hydrolase NudL OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=nudL P... NUDL_SALPA - Uncharacterized Nudix hydrolase NudL OS=Salmonella paratyphi A GN=nudL PE=3 SV=1 NUDL_SALPK - Uncharacterized Nudix hydrolase NudL OS=Salmonella paratyphi A (strain AKU_12601) GN=nudL PE=3 SV=1 NUDL_SALA4 - Uncharacterized Nudix hydrolase NudL OS=Salmonella agona (strain SL483) GN=nudL PE=3 SV=1 NUDL_SALHS - Uncharacterized Nudix hydrolase NudL OS=Salmonella heidelberg (strain SL476) GN=nudL PE=3 SV=1 gi\|168820575, gi... - gi\|205342622\|gb\|EDZ29386.1\| hydrolase, nudix family [Salmonella enterica subsp. enterica serovar Wel... gi\|168241418, gi... - gi\|205339467\|gb\|EDZ26231.1\| hydrolase, nudix family [Salmonella enterica subsp. enterica serovar Hei...	158.0	[0..1]	[192..1]
NUDL_SALPB - Uncharacterized Nudix hydrolase nudL OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=nudL... gi\|238912110 - gi\|238912110\|ref\|ZP_04655947.1\| hypothetical protein SentesTe_13391 [Salmonella enterica subsp. ente... NUDL_SALCH - Uncharacterized Nudix hydrolase nudL OS=Salmonella choleraesuis GN=nudL PE=3 SV=1 NUDL_SALCH - Uncharacterized Nudix hydrolase NudL OS=Salmonella choleraesuis GN=nudL PE=3 SV=1 NUDL_SALTY - Uncharacterized Nudix hydrolase NudL OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)... gi\|16760715 - gi\|16760715\|ref\|NP_456332.1\| hypothetical protein STY1955 [Salmonella enterica subsp. enterica serov... NUDL_SALTI, YEAB... - Uncharacterized Nudix hydrolase yeaB - Salmonella typhi, Uncharacterized Nudix hydrolase nudL OS=Sal... NUDL_SALTI - Uncharacterized Nudix hydrolase NudL OS=Salmonella typhi GN=nudL PE=3 SV=1 lcl\|NC_016856.1_... - [gene=yeaB] [protein=hypothetical protein] [protein_id=YP_005237766.1] [location=1933939..1934517] NUDL_SALSV - Uncharacterized Nudix hydrolase NudL OS=Salmonella schwarzengrund (strain CVM19633) GN=nudL PE=3 SV=... gi\|197243474, gi... - gi\|197265219\|ref\|ZP_03165293.1\| hydrolase, nudix family [Salmonella enterica subsp. enterica serovar... gi\|200390948, gi... - gi\|200390948\|ref\|ZP_03217559.1\| hydrolase, nudix family [Salmonella enterica subsp. enterica serovar... NUDL_SALEP - Uncharacterized Nudix hydrolase NudL OS=Salmonella enteritidis PT4 (strain P125109) GN=nudL PE=3 SV=... gi\|205331753, gi... - gi\|205331753\|gb\|EDZ18517.1\| hydrolase, nudix family [Salmonella enterica subsp. enterica serovar Ken... NUDL_SALTY - Uncharacterized Nudix hydrolase NudL OS=Salmonella typhimurium GN=nudL PE=3 SV=1 gi\|168237891, gi... - gi\|197289254\|gb\|EDY28621.1\| hydrolase, nudix family protein [Salmonella enterica subsp. enterica ser... gi\|168259937, gi... - gi\|205350926\|gb\|EDZ37557.1\| hydrolase, nudix family [Salmonella enterica subsp. enterica serovar Had... gi\|194469460, gi... - gi\|194469460\|ref\|ZP_03075444.1\| hydrolase, nudix family [Salmonella enterica subsp. enterica serovar... NUDL_SALTY, YEAB... - Uncharacterized Nudix hydrolase yeaB - Salmonella typhimurium, Uncharacterized Nudix hydrolase nudL ... NUDL_SALCH - Uncharacterized Nudix hydrolase NudL OS=Salmonella choleraesuis (strain SC-B67) GN=nudL PE=3 SV=1 gi\|167553494, gi... - gi\|205322084\|gb\|EDZ09923.1\| hydrolase, nudix family [Salmonella enterica subsp. enterica serovar Sai... gi\|167993280, gi... - gi\|205328681\|gb\|EDZ15445.1\| hydrolase, nudix family [Salmonella enterica subsp. enterica serovar 4,[... NUDL_SALPB - Uncharacterized Nudix hydrolase NudL OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=nudL... gi\|214001095 - gi\|214001095\|ref\|ZP_03411830.1\| hypothetical protein Salmonellentericaenterica_11425 [Salmonella ent... NUDL_SALPC - Uncharacterized Nudix hydrolase NudL OS=Salmonella paratyphi C (strain RKS4594) GN=nudL PE=3 SV=1 gi\|213052616 - gi\|213052616\|ref\|ZP_03345494.1\| hypothetical protein Salmoneentericaenterica_06676 [Salmonella enter... gi\|213426601 - gi\|213426601\|ref\|ZP_03359351.1\| hypothetical protein SentesTyphi_13898 [Salmonella enterica subsp. e... gi\|213583671 - gi\|213583671\|ref\|ZP_03365497.1\| hypothetical protein SentesTyph_21615 [Salmonella enterica subsp. en... gi\|213650133 - gi\|213650133\|ref\|ZP_03380186.1\| hypothetical protein SentesTy_24524 [Salmonella enterica subsp. ente...	157.0	[0..1]	[192..1]
gi\|29137154, gi\|... - gi\|29141527\|ref\|NP_804869.1\| hypothetical protein t1052 [Salmonella enterica subsp. enterica serovar...	156.0	[0..1]	[192..1]
NUDL_ERWCT - Uncharacterized Nudix hydrolase NudL OS=Erwinia carotovora subsp. atroseptica GN=nudL PE=3 SV=1 NUDL_PECAS - Uncharacterized Nudix hydrolase NudL OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672...	156.0	[0..1]	[192..1]
gi\|78693756, gi\|... - gi\|78693756\|ref\|ZP_00858270.1\| nudix hydrolase [Bradyrhizobium sp. BTAi1], gi\|78519311\|gb\|EAP32608.1...	155.0	[0..21]	[191..54]
RPA1187 - RPA1187 NUDIX hydrolase 1298486:1299151 forward MW:24187	155.0	[0..21]	[191..51]
gi\|113970463, gi... - gi\|82497991\|ref\|ZP_00883510.1\| MutT/nudix family protein [Shewanella sp. MR-4], gi\|82404004\|gb\|EAP44...	155.0	[0..6]	[191..1]
gi\|27377578, gi\|... - gi\|27377578\|ref\|NP_769107.1\| hypothetical protein blr2467 [Bradyrhizobium japonicum USDA 110], gi\|27...	155.0	[0..21]	[189..3]
NUDL_PHOLL - Uncharacterized Nudix hydrolase NudL OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 ... NUDL_PHOLL - Uncharacterized Nudix hydrolase nudL OS=Photorhabdus luminescens subsp. laumondii GN=nudL PE=3 SV=1	155.0	[0..6]	[189..2]
gi\|78504245, gi\|... - gi\|78688003\|ref\|ZP_00852731.1\| MutT/nudix family protein [Shewanella sp. ANA-3], gi\|78504245\|gb\|EAP1...	154.0	[0..6]	[191..1]

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Predicted Domain #1

Region A:
Residues: [1-192]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEYRSLTLDD FLSRFQLLRP QINRETLNHR QAAVLIPIVR RPQPGLLLTQ RSIHLRKHAG  60
   61 QVAFPGGAVD DTDASAIAAA LREAEEEVAI PPSAVEVIGV LPPVDSVTGY QVTPVVGIIP 120
  121 PDLPYRASED EVSAVFEMPL AQALHLGRYH PLDIYRRGDS HRVWLSWYEQ YFVWGMTAGI 180
  181 IRELALQIGV KP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.69897
Match:	1nqyA
Description:	Coenzyme A pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.86119802438676	bayes_pls_golite062009
hydrolase activity	0.97790691270817	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.544115189438	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.54377405132398	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: