YRC Public Data Repository - Protein Structure Prediction

Protein:	YDHF_ECOLI
Organism:	Escherichia coli
Length:	298 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDHF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|53765455, gi\|... - gi\|75906333\|ref\|YP_320629.1\| aldo/keto reductase [Anabaena variabilis ATCC 29413], gi\|75700058\|gb\|AB...	321.0	[0..1]	[297..1]
gi\|67861532, gi\|... - gi\|67931231\|ref\|ZP_00524395.1\| Aldo/keto reductase [Solibacter usitatus Ellin6076], gi\|67861532\|gb\|E...	316.0	[0..2]	[297..1]
gi\|159893771, gi... - gi\|159900732\|ref\|YP_001546979.1\| aldo/keto reductase [Herpetosiphon aurantiacus ATCC 23779], gi\|1598...	315.0	[0..2]	[293..1]
gi\|241904018, gi... - gi\|241904018\|ref\|ZP_04788730.1\| aldo/keto reductase [Thermoanaerobacter brockii subsp. finnii Ako-1]... gi\|166856834, gi... - gi\|76796502\|ref\|ZP_00778863.1\| Aldo/keto reductase [Thermoanaerobacter ethanolicus ATCC 33223], gi\|7...	314.0	[0..2]	[298..1]
gi\|56420510, gi\|... - gi\|56420510\|ref\|YP_147828.1\| K+ channel beta subunit [Geobacillus kaustophilus HTA426], gi\|56380352\|...	312.0	[0..2]	[293..1]
gi\|76166661, gi\|... - gi\|76258577\|ref\|ZP_00766232.1\| Aldo/keto reductase [Chloroflexus aurantiacus J-10-fl], gi\|76166661\|g... gi\|222524644, gi... - gi\|222524644\|ref\|YP_002569115.1\| aldo/keto reductase [Chloroflexus sp. Y-400-fl], gi\|222448523\|gb\|AC...	309.0	[0..2]	[297..1]
gi\|68513528, gi\|... - gi\|68560179\|ref\|ZP_00599494.1\| Aldo/keto reductase [Rubrobacter xylanophilus DSM 9941], gi\|68513528\|...	309.0	[0..2]	[293..1]
gi\|33602077, gi\|... - gi\|33602077\|ref\|NP_889637.1\| putative oxidoreductase [Bordetella bronchiseptica RB50], gi\|33576515\|e...	309.0	[0..2]	[297..1]
gi\|33596263 - gi\|33596263\|ref\|NP_883906.1\| putative oxidoreductase [Bordetella parapertussis 12822] gi\|33573266 - gi\|33573266\|emb\|CAE36928.1\| putative oxidoreductase [Bordetella parapertussis]	309.0	[0..2]	[297..1]
gi\|108467371, gi... - gi\|108763491\|ref\|YP_632183.1\| aldo/keto reductase family oxidoreductase [Myxococcus xanthus DK 1622]...	309.0	[0..2]	[297..1]

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Predicted Domain #1

Region A:
Residues: [1-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQRITIAPQ GPEFSRFVMG YWRLMDWNMS ARQLVSFIEE HLDLGVTTVD HADIYGGYQC  60
   61 EAAFGEALKL APHLRERMEI VSKCGIATTA REENVIGHYI TDRDHIIKSA EQSLINLATD 120
  121 HLDLLLIHRP DPLMDADEVA DAFKHLHQSG KVRHFGVSNF TPAQFALLQS RLPFTLATNQ 180
  181 VEISPVHQPL LLDGTLDQLQ QLRVRPMAWS CLGGGRLFND DYFQPLRDEL AVVAEELNAG 240
  241 SIEQVVYAWV LRLPSQPLPI IGSGKIERVR AAVEAETLKM TRQQWFRIRK AALGYDVP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.39794
Match:	1ur3M
Description:	Crystal structure of the apo form of the E.coli ydhF protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.68179794468736	bayes_pls_golite062009
aldo-keto reductase activity	0.756121063182699	bayes_pls_golite062009
oxidoreductase activity	0.409822872480823	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: