YRC Public Data Repository - Protein Structure Prediction

Protein:	YCJQ_ECOLI
Organism:	Escherichia coli
Length:	350 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YCJQ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|238727202, gi... - gi\|77978816\|ref\|ZP_00834240.1\| COG1062: Zn-dependent alcohol dehydrogenases, class III [Yersinia int...	306.0	[0..2]	[350..7]
gi\|238715026, gi... - gi\|77958654\|ref\|ZP_00822684.1\| COG1062: Zn-dependent alcohol dehydrogenases, class III [Yersinia ber...	306.0	[0..2]	[350..7]
gi\|90325090, gi\|... - gi\|90413906\|ref\|ZP_01221892.1\| putative alcohol dehydrogenase class III [Photobacterium profundum 3T...	304.0	[0..2]	[350..9]
gi\|160861160, gi... - gi\|160875638\|ref\|YP_001554954.1\| S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydr... gi\|68542288, gi\|... - gi\|68542288\|ref\|ZP_00582021.1\| Zinc-containing alcohol dehydrogenase superfamily [Shewanella baltica... gi\|77816052, gi\|... - gi\|77816052\|ref\|ZP_00815261.1\| Zinc-containing alcohol dehydrogenase superfamily [Shewanella putrefa... gi\|153000927, gi... - gi\|153000927\|ref\|YP_001366608.1\| S-(hydroxymethyl)glutathione dehydrogenase [Shewanella baltica OS18... gi\|146863790, gi... - gi\|217973117\|ref\|YP_002357868.1\| S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydr...	304.0	[0..2]	[350..12]
gi\|54308673, gi\|... - gi\|54308673\|ref\|YP_129693.1\| putative alcohol dehydrogenase class III [Photobacterium profundum SS9]...	304.0	[0..2]	[350..9]
gi\|238788842, gi... - gi\|77973854\|ref\|ZP_00829398.1\| COG1062: Zn-dependent alcohol dehydrogenases, class III [Yersinia fre...	304.0	[0..2]	[350..7]
gi\|88797687, gi\|... - gi\|88797687\|ref\|ZP_01113275.1\| zinc-binding dehydrogenase [Reinekea sp. MED297], gi\|88779364\|gb\|EAR1...	303.0	[0..3]	[345..11]
gi\|83845254, gi\|... - gi\|83944007\|ref\|ZP_00956464.1\| zinc-binding dehydrogenase [Sulfitobacter sp. EE-36], gi\|83845254\|gb\|...	303.0	[0..3]	[350..10]
gi\|88860103, gi\|... - gi\|88860103\|ref\|ZP_01134742.1\| alcohol dehydrogenase class III [Pseudoalteromonas tunicata D2], gi\|8...	302.0	[0..2]	[350..9]
gi\|166211733, gi... - gi\|166211733\|ref\|ZP_02237768.1\| S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydro... gi\|170024796, gi... - gi\|170024796\|ref\|YP_001721301.1\| S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydr... gi\|229703701, gi... - gi\|229894303\|ref\|ZP_04509486.1\| Alcohol dehydrogenase class III;Glutathione-dependent formaldehyde d... gi\|186894941, gi... - gi\|186894941\|ref\|YP_001872053.1\| S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydr... Q66C89\|Q66C89_YERPS - Probable alcohol dehydrogenase / formaldehyde dehydrogenase - Yersinia pseudotuberculosis gi\|162351589, gi... - gi\|77635264\|ref\|ZP_00797351.1\| COG1062: Zn-dependent alcohol dehydrogenases, class III [Yersinia pes... gi\|153947808, gi... - gi\|77628736\|ref\|ZP_00791322.1\| COG1062: Zn-dependent alcohol dehydrogenases, class III [Yersinia pse... gi\|51595854, gi\|... - gi\|51595854\|ref\|YP_070045.1\| alcohol dehydrogenase/formaldehyde dehydrogenase [Yersinia pseudotuberc... gi\|145598759, gi... - gi\|145598759\|ref\|YP_001162835.1\| alcohol dehydrogenase [Yersinia pestis Pestoides F], gi\|145210455\|g... gi\|45436077, gi\|... - gi\|45441217\|ref\|NP_992756.1\| alcohol dehydrogenase [Yersinia pestis biovar Microtus str. 91001], gi\|...	302.0	[0..2]	[350..7]

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Predicted Domain #1

Region A:
Residues: [1-350]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKLVATAPR VAALVEYEDR AILANEVKIR VRFGAPKHGT EVVDFRAASP FIDEDFNGEW  60
   61 QMFTPRPADA PRGIEFGKFQ LGNMVVGDII ECGSDVTDYA VGDSVCGYGP LSETVIINAV 120
  121 NNYKLRKMPQ GSSWKNAVCY DPAQFAMSGV RDANVRVGDF VVVVGLGAIG QIAIQLAKRA 180
  181 GASVVIGVDP IAHRCDIARR HGADFCLNPI GTDVGKEIKT LTGKQGADVI IETSGYADAL 240
  241 QSALRGLAYG GTISYVAFAK PFAEGFNLGR EAHFNNAKIV FSRACSEPNP DYPRWSRKRI 300
  301 EETCWELLMN GYLNCEDLID PVVTFANSPE SYMQYVDQHP EQSIKMGVTF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.045757
Match:	1rjwA
Description:	CRYSTAL STRUCTURE OF NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE FROM BACILLUS STEAROTHERMOPHILUS STRAIN LLD-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.16785883389468	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.3919444853018	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.27605103494323	bayes_pls_golite062009
oxidoreductase activity	1.13814306448308	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: