YRC Public Data Repository - Protein Structure Prediction

Protein:	YAIM_ECOLI
Organism:	Escherichia coli
Length:	277 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YAIM_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|24378638, gi\|... - gi\|24378638\|ref\|NP_720593.1\| putative esterase [Streptococcus mutans UA159], gi\|24376496\|gb\|AAN57899...	247.0	[0..1]	[277..1]
gi\|114565208, gi... - gi\|69953478\|ref\|ZP_00640589.1\| Carboxylesterase [Shewanella frigidimarina NCIMB 400], gi\|69163463\|gb...	245.0	[0..1]	[276..3]
gi\|90438696, gi\|... - gi\|90579811\|ref\|ZP_01235619.1\| putative esterase [Vibrio angustum S14], gi\|90438696\|gb\|EAS63879.1\| p...	244.0	[0..1]	[275..3]
gi\|78368020, gi\|... - gi\|78368020\|ref\|ZP_00838275.1\| Carboxylesterase [Shewanella sp. PV-4], gi\|78359932\|gb\|EAP01779.1\| Ca...	243.0	[0..1]	[274..3]
gi\|91795111, gi\|... - gi\|91795111\|ref\|YP_564762.1\| carboxylesterase [Shewanella denitrificans OS217], gi\|91717113\|gb\|ABE57...	242.0	[0..1]	[275..3]
gi\|89051071, gi\|... - gi\|89073118\|ref\|ZP_01159657.1\| putative esterase [Photobacterium sp. SKA34], gi\|89051071\|gb\|EAR56528...	241.0	[0..1]	[275..3]
gi\|71145306, gi\|... - gi\|71279566\|ref\|YP_267568.1\| putative esterase [Colwellia psychrerythraea 34H], gi\|71145306\|gb\|AAZ25...	241.0	[0..1]	[275..7]
gi\|114649560 - gi\|114649560\|ref\|XP_001150093.1\| PREDICTED: esterase D/formylglutathione hydrolase isoform 2 [Pan tr...	240.0	[0..1]	[275..37]
ESTD_RAT - S-formylglutathione hydrolase OS=Rattus norvegicus GN=Esd PE=2 SV=1	240.0	[0..1]	[275..3]

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Predicted Domain #1

Region A:
Residues: [1-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELIEKHVSF GGWQNMYRHY SQSLKCEMNV GVYLPPKAAN EKLPVLYWLS GLTCNEQNFI  60
   61 TKSGMQRYAA EHNIIVVAPD TSPRGSHVAD ADRYDLGQGA GFYLNATQAP WNEHYKMYDY 120
  121 IRNELPDLVM HHFPATAKKS ISGHSMGGLG ALVLALRNPD EYVSVSAFSP IVSPSQVPWG 180
  181 QQAFAAYLAE NKDAWLDYDP VSLISQGQRV AEIMVDQGLS DDFYAEQLRT PNLEKICQEM 240
  241 NIKTLIRYHE GYDHSYYFVS SFIGEHIAYH ANKLNMR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	42.69897
Match:	1pv1A
Description:	Crystal Structure Analysis of Yeast Hypothetical Protein: YJG8_YEAST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
S-formylglutathione hydrolase activity	2.11404818814754	bayes_pls_golite062009
hydrolase activity	1.75934962198703	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.09488027320166	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: