YRC Public Data Repository - Protein Structure Prediction

Protein:	YAIC_ECOLI
Organism:	Escherichia coli
Length:	371 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YAIC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|218350578, gi... - gi\|218693846\|ref\|YP_002401513.1\| diguanylate cyclase AdrA [Escherichia coli 55989], gi\|218350578\|emb... gi\|218552948, gi... - gi\|218552948\|ref\|YP_002385861.1\| diguanylate cyclase AdrA [Escherichia coli IAI1], gi\|218359716\|emb\|... gi\|81244287, gi\|... - gi\|82542876\|ref\|YP_406823.1\| diguanylate cyclase AdrA [Shigella boydii Sb227], gi\|81244287\|gb\|ABB649... gi\|157065584, gi... - gi\|157159904\|ref\|YP_001457222.1\| diguanylate cyclase AdrA [Escherichia coli HS], gi\|157065584\|gb\|ABV... gi\|157157429, gi... - gi\|157157429\|ref\|YP_001461563.1\| diguanylate cyclase AdrA [Escherichia coli E24377A], gi\|157079459\|g...	296.0	[0..1]	[371..1]
gi\|82775715, gi\|... - gi\|82775715\|ref\|YP_402062.1\| diguanylate cyclase AdrA [Shigella dysenteriae Sd197], gi\|81239863\|gb\|A...	296.0	[0..1]	[371..1]
gi\|30040125, gi\|... - gi\|30061881\|ref\|NP_836052.1\| diguanylate cyclase AdrA [Shigella flexneri 2a str. 2457T], gi\|30040125... gi\|24111763, gi\|... - gi\|24111763\|ref\|NP_706273.1\| diguanylate cyclase AdrA [Shigella flexneri 2a str. 301], gi\|24050549\|g...	296.0	[0..1]	[371..1]
gi\|110804408, gi... - gi\|110804408\|ref\|YP_687928.1\| diguanylate cyclase AdrA [Shigella flexneri 5 str. 8401], gi\|110613956...	296.0	[0..1]	[371..1]
gi\|217322008, gi... - gi\|217325787\|ref\|ZP_03441871.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. TW14... gi\|208807537, gi... - gi\|208807537\|ref\|ZP_03249874.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC42... gi\|254791563, gi... - gi\|254791563\|ref\|YP_003076400.1\| predicted diguanylate cyclase [Escherichia coli O157:H7 str. TW1435... gi\|208815128, gi... - gi\|208815128\|ref\|ZP_03256307.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC40... gi\|208823086, gi... - gi\|208823086\|ref\|ZP_03263404.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC40... gi\|209396741, gi... - gi\|209396741\|ref\|YP_002269023.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC4... gi\|187768330, gi... - gi\|187768330\|gb\|EDU32174.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC4196],... gi\|188999344, gi... - gi\|188999344\|gb\|EDU68330.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC4076],... gi\|168786219, gi... - gi\|189373607\|gb\|EDU92023.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC869], ... gi\|195938555 - gi\|195938555\|ref\|ZP_03083937.1\| diguanylate cyclase AdrA [Escherichia coli O157:H7 str. EC4024] gi\|188015870, gi... - gi\|188015870\|gb\|EDU53992.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC4113],... gi\|189355958, gi... - gi\|189355958\|gb\|EDU74377.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC4401],... gi\|189362362, gi... - gi\|189362362\|gb\|EDU80781.1\| MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC4486],... gi\|15829689, gi\|... - gi\|15829689\|ref\|NP_308462.1\| hypothetical protein ECs0435 [Escherichia coli O157:H7], gi\|13359892\|db... gi\|25389817, gi\|... - pir\|\|G85533 hypothetical protein yaiC [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|15800111, gi\|... - gi\|15800111\|ref\|NP_286123.1\| diguanylate cyclase AdrA [Escherichia coli O157:H7 EDL933], gi\|12513225... gi\|15829689, gi\|... - gi\|15829689\|ref\|NP_308462.1\| diguanylate cyclase AdrA [Escherichia coli O157:H7 str. Sakai], gi\|1335...	296.0	[0..1]	[371..1]
gi\|110640646, gi... - gi\|110640646\|ref\|YP_668374.1\| diguanylate cyclase AdrA [Escherichia coli 536], gi\|110342238\|gb\|ABG68... gi\|218557295, gi... - gi\|218557295\|ref\|YP_002390208.1\| diguanylate cyclase AdrA [Escherichia coli S88], gi\|218364064\|emb\|C... gi\|91209450, gi\|... - gi\|91209450\|ref\|YP_539436.1\| diguanylate cyclase AdrA [Escherichia coli UTI89], gi\|91071024\|gb\|ABE05... gi\|117622648, gi... - gi\|117622648\|ref\|YP_851561.1\| diguanylate cyclase AdrA [Escherichia coli APEC O1], gi\|115511772\|gb\|A... gi\|237707626, gi... - gi\|237707626\|ref\|ZP_04538107.1\| diguanylate cyclase AdrA [Escherichia sp. 3_2_53FAA], gi\|226898836\|g...	293.0	[0..1]	[371..1]
gi\|75230111, gi\|... - gi\|75230111\|ref\|ZP_00716615.1\| COG2199: FOG: GGDEF domain [Escherichia coli B7A], gi\|191166731\|ref\|Z... gi\|75209942, gi\|... - gi\|75209942\|ref\|ZP_00710131.1\| COG2199: FOG: GGDEF domain [Escherichia coli B171], gi\|194428836\|ref\|... gi\|75194605 - gi\|75194605\|ref\|ZP_00704675.1\| COG2199: FOG: GGDEF domain [Escherichia coli HS] gi\|75189453 - gi\|75189453\|ref\|ZP_00702720.1\| COG2199: FOG: GGDEF domain [Escherichia coli E24377A]	285.0	[0..6]	[371..1]
gi\|83585695 - gi\|83585695\|ref\|ZP_00924337.1\| COG2199: FOG: GGDEF domain [Escherichia coli 101-1] gi\|83570347 - gi\|83570347\|ref\|ZP_00921792.1\| COG2199: FOG: GGDEF domain [Shigella dysenteriae 1012]	284.0	[0..6]	[371..1]
gi\|75256758 - gi\|75256758\|ref\|ZP_00728363.1\| COG2199: FOG: GGDEF domain [Escherichia coli E22]	283.0	[0..6]	[371..1]
gi\|75237233 - gi\|75237233\|ref\|ZP_00721280.1\| COG2199: FOG: GGDEF domain [Escherichia coli E110019]	283.0	[0..6]	[371..1]

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Predicted Domain #1

Region A:
Residues: [1-134]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFPKIMNDEN FFKKAAAHGE EPPLTPQNEH QRSGLRFARR VRLPRAVGLA GMFLPIASTL  60
   61 VSHPPPGWWW LVLVGWAFVW PHLAWQIASR AVDPLSREIY NLKTDAVLAG MWVGVMGVNV 120
  121 LPSTAMLMIM CLNL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	43.468521
Match:	PF05230.2
Description:	No description for PF05230.2 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [135-371]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAGGPRLFV AGLVLMVVSC LVTLELTGIT VSFNSAPLEW WLSLPIIVIY PLLFGWVSYQ  60
   61 TATKLAEHKR RLQVMSTRDG MTGVYNRRHW ETMLRNEFDN CRRHNRDATL LIIDIDHFKS 120
  121 INDTWGHDVG DEAIVALTRQ LQITLRGSDV IGRFGGDEFA VIMSGTPAES AITAMLRVHE 180
  181 GLNTLRLPNT PQVTLRISVG VAPLNPQMSH YREWLKSADL ALYKAKKAGR NRTEVAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.69897
Match:	1w25A
Description:	Response regulator PleD in complex with c-diGMP
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits