YRC Public Data Repository - Protein Structure Prediction

Protein:	XERC_ECOLI
Organism:	Escherichia coli
Length:	298 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for XERC_ECOLI.

Description	E-value	Query Range	Subject Range
XERC_OCEIH - Tyrosine recombinase XerC OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HT... XERC_OCEIH - Tyrosine recombinase xerC OS=Oceanobacillus iheyensis GN=xerC PE=3 SV=1	250.0	[0..1]	[298..1]
gi\|77545197, gi\|... - gi\|77919114\|ref\|YP_356929.1\| site-specific recombinase [Pelobacter carbinolicus DSM 2380], gi\|775451...	244.0	[0..4]	[294..1]
gi\|98662087 - gi\|98662087\|dbj\|GAA00976.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	240.0	[0..4]	[294..47]
XERC_BACLD - Tyrosine recombinase XerC OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12...	240.0	[0..1]	[298..1]
gi\|193068085, gi... - gi\|75238264\|ref\|ZP_00722263.1\| COG4973: Site-specific recombinase XerC [Escherichia coli E110019], g...	240.0	[0..1]	[298..1]
gi\|51892959, gi\|... - gi\|51892959\|ref\|YP_075650.1\| recombinase [Symbiobacterium thermophilum IAM 14863], gi\|51856648\|dbj\|B...	239.0	[0..4]	[294..1]
XERD_STAHJ - Tyrosine recombinase XerD OS=Staphylococcus haemolyticus (strain JCSC1435) GN=xerD PE=3 SV=1	239.0	[0..4]	[294..1]
gi\|83573258, gi\|... - gi\|83590344\|ref\|YP_430353.1\| tyrosine recombinase XerD subunit [Moorella thermoacetica ATCC 39073], ...	238.0	[0..4]	[294..1]
gi\|85722142, gi\|... - gi\|85859051\|ref\|YP_461253.1\| integrase/recombinase [Syntrophus aciditrophicus SB], gi\|85722142\|gb\|AB...	238.0	[0..6]	[294..4]
gi\|12518679, gi\|... - gi\|15804400\|ref\|NP_290440.1\| site-specific tyrosine recombinase XerC [Escherichia coli O157:H7 EDL93... gi\|209753248, gi... - pir\|\|H86067 site-specific recombinase XerC [imported] - Escherichia coli (strain O157:H7, substrain ... gi\|208813099, gi... - gi\|208813099\|ref\|ZP_03254428.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC4045], gi... gi\|208806813, gi... - gi\|208806813\|ref\|ZP_03249150.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC4206], gi... gi\|195938100 - gi\|195938100\|ref\|ZP_03083482.1\| site-specific tyrosine recombinase XerC [Escherichia coli O157:H7 st... gi\|189376684, gi... - gi\|189376684\|gb\|EDU95100.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC508], gi\|1688... gi\|217322415, gi... - gi\|217326194\|ref\|ZP_03442278.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. TW14588], g... XERC_ECO5E - Tyrosine recombinase XerC OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=xerC PE=3 SV=1 gi\|208741424, gi... - gi\|208821301\|ref\|ZP_03261621.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC4042], gi... gi\|189358976, gi... - gi\|189358976\|gb\|EDU77395.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC4401], gi\|168... gi\|168750377, gi... - gi\|188015455\|gb\|EDU53577.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC4113], gi\|168... gi\|168780710, gi... - gi\|189001561\|gb\|EDU70547.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC4076], gi\|168... gi\|187768906, gi... - gi\|187768906\|gb\|EDU32750.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC4196], gi\|168... gi\|168768092, gi... - gi\|189362670\|gb\|EDU81089.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC4486], gi\|168... gi\|189365973, gi... - gi\|189365973\|gb\|EDU84389.1\| tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC4501], gi\|168... XERC_ECO57 - Tyrosine recombinase XerC OS=Escherichia coli O157:H7 GN=xerC PE=3 SV=1 gi\|254795807, gi... - gi\|254795807\|ref\|YP_003080644.1\| site-specific tyrosine recombinase [Escherichia coli O157:H7 str. T... gi\|15833995, gi\|... - gi\|15833995\|ref\|NP_312768.1\| site-specific tyrosine recombinase XerC [Escherichia coli O157:H7 str. ...	238.0	[0..1]	[298..1]

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Predicted Domain #1

Region A:
Residues: [1-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDLHTDVER YLRYLSVERQ LSPITLLNYQ RQLEAIINFA SENGLQSWQQ CDVTMVRNFA  60
   61 VRSRRKGLGA ASLALRLSAL RSFFDWLVSQ NELKANPAKG VSAPKAPRHL PKNIDVDDMN 120
  121 RLLDIDINDP LAVRDRAMLE VMYGAGLRLS ELVGLDIKHL DLESGEVWVM GKGSKERRLP 180
  181 IGRNAVAWIE HWLDLRDLFG SEDDALFLSK LGKRISARNV QKRFAEWGIK QGLNNHVHPH 240
  241 KLRHSFATHM LESSGDLRGV QELLGHANLS TTQIYTHLDF QHLASVYDAA HPRAKRGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.221849
Match:	1a0pA
Description:	SITE-SPECIFIC RECOMBINASE, XERD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
site-specific recombinase activity	4.99325011803106	bayes_pls_golite062009
integrase activity	3.60695091575172	bayes_pls_golite062009
catalytic activity	2.22520758916604	bayes_pls_golite062009
structure-specific DNA binding	0.11292854906722	bayes_pls_golite062009
DNA binding	0.10970863758177	bayes_pls_golite062009
nucleic acid binding	0.06580979261817	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: